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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC00936
TatC family signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00936

Description

The following proteins have been shown [1] to share regions of similarities:

  • Escherichia coli hypothetical protein yigU and HI0188, the corresponding Haemophilus influenzae protein.
  • Bacillus subtilis hypothetical protein ycbT.
  • Mycobacterium tuberculosis hypothetical protein MtCY49.33c and U2126A, the corresponding Mycobacterium leprae protein.
  • Synechocystis strain PCC 6803 hypothetical protein sll0194.
  • Odontella sinensis and Porphyra purpurea chlroplast hypothetical protein ycf43.

These proteins have from 245 to 317 amino acids and seem to contain at least six or seven transmembrane regions. As a signature pattern, we selected a conserved region located in the central section of these proteins.

Last update:

April 2006 / Pattern revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

TATC, PS01218; TatC family signature  (PATTERN)


Reference

1AuthorsBairoch A. Rudd K.E.
SourceUnpublished observations (1996).



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