PROSITE documentation PDOC51137VM domain profile
Description
In Drosophila melanogaster the vitelline membrane (VM) is the first layer of the eggshell produced by the follicular epithelium. It is composed of at least four different proteins. VM proteins are similarly organized with a central highly conserved 38-amino acid domain which is flanked by unrelated regions. Since the surrounding regions have diverged significantly, it is possible that the VM domain is of key importance in VM protein structure [1,2].
The profile we developed covers the entire VM domain.
Last update:June 2005 / First entry.
-------------------------------------------------------------------------------
Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Scherer L.J. Harris D.H. Petri W.H. |
| Title | Drosophila vitelline membrane genes contain a 114 base pair region of highly conserved coding sequence. | |
| Source | Dev. Biol. 130:786-788(1988). | |
| PubMed ID | 3143615 |
| 2 | Authors | Scherer L.J. Harris D.H. White M.K. Steel L.F. Jin J. Petri W.H. |
| Title | Comparative analysis of the sequence and structure of two Drosophila melanogaster genes encoding vitelline membrane proteins. | |
| Source | Gene 136:121-127(1993). | |
| PubMed ID | 8293994 |
Copyright
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
Miscellaneous
View entry in original PROSITE document format
View entry in raw text format (no links)