Home  |  Contact
PROSITE documentation PDOC51817

Peptidase family A3B domain profile





Description

Rice tungro bacilliform virus (RTBV) is a pararetrovirus, and a member of the family Caulimoviridae in the genus Tungrovirus [E1]. RTBV has a long open reading frame that encodes a large polyprotein (P3). P3 contains a putative movement protein (MP), the capsid protein (CP), the aspartate protease (PR) and the reverse transcriptase (RT) with a ribonuclease H activity. PR is a member of the cluster of retroviral proteases and serves to proteolytically process P3. The sequence DSGS is believed to be the RTBV protease active site [1]. The RTBV PR domain forms peptidase family A3 subfamily B [E2].

The profile we developed covers the entire peptidase family A3B domain.

Last update:

September 2016 / First entry.

-------------------------------------------------------------------------------

Technical section

PROSITE method (with tools and information) covered by this documentation:

PEPTIDASE_A3B, PS51817; Peptidase family A3B domain profile  (MATRIX)


References

1AuthorsMarmey P. Rojas-Mendoza A. de Kochko A. Beachy R.N. Fauquet C.M.
TitleCharacterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein.
SourceVirol. J. 2:33-33(2005).
PubMed ID15831103
DOI10.1186/1743-422X-2-33

E1Titlehttps://viralzone.expasy.org/124?outline=all_by_species

E2Titlehttps://www.ebi.ac.uk/merops/cgi-bin/famsum?family=A3



PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

Miscellaneous

View entry in original PROSITE document format
View entry in raw text format (no links)