PROSITE documentation PDOC51817Peptidase family A3B domain profile
Rice tungro bacilliform virus (RTBV) is a pararetrovirus, and a member of the family Caulimoviridae in the genus Tungrovirus [E1]. RTBV has a long open reading frame that encodes a large polyprotein (P3). P3 contains a putative movement protein (MP), the capsid protein (CP), the aspartate protease (PR) and the reverse transcriptase (RT) with a ribonuclease H activity. PR is a member of the cluster of retroviral proteases and serves to proteolytically process P3. The sequence DSGS is believed to be the RTBV protease active site [1]. The RTBV PR domain forms peptidase family A3 subfamily B [E2].
The profile we developed covers the entire peptidase family A3B domain.
Last update:September 2016 / First entry.
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PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Marmey P. Rojas-Mendoza A. de Kochko A. Beachy R.N. Fauquet C.M. |
| Title | Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein. | |
| Source | Virol. J. 2:33-33(2005). | |
| PubMed ID | 15831103 | |
| DOI | 10.1186/1743-422X-2-33 |
| E1 | Title | https://viralzone.expasy.org/124?outline=all_by_species |
| E2 | Title | https://www.ebi.ac.uk/merops/cgi-bin/famsum?family=A3 |
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