PROSITE logo

PROSITE entry PS50016


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50016
Entry name [info] ZF_PHD_2
Accession [info] PS50016
Entry type [info] MATRIX
Date [info] 01-APR-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50016
Associated ProRule [info] PRU00146

Name and characterization of the entry

Description [info] Zinc finger PHD-type profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=54;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=51;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4800000; R2=0.0089000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3510.1113281; R2=3.0049100; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=789; H_SCORE=5881; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=565; H_SCORE=5208; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;

...
 
                A    B    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y    Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='N';  M=  -6,  -2, -11,  -4,  -7, -14,  -8,  -8, -17,  -6, -16, -11,   1, -19,  -6,  -4,   0,  -2, -12, -25,  -8,  -7;
/M: SY='N';  M=  -4,  -7, -24, -10,  -8, -14, -15,  -8,  -7,  -2,  -9,  -4,  -4, -14,  -6,  -4,  -6,  -4,  -6, -20,  -6,  -8;
/M: SY='F';  M= -10, -19, -20, -23, -16,  17, -21, -12,   2, -16,   3,   3, -16, -23, -16, -13, -11,  -4,   2,  -9,  12, -16;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30, -30, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/I:         I=-6; MI=-32; MD=-32; IM=-32;
/M: SY='Y';  M=  -6,  -8, -11,  -8,  -5,  -2, -13,  -4,  -9,  -8,  -6,  -3,  -7, -10,  -6,  -7,  -5,  -5,  -9, -14,   2,  -6; D=-6;
/I:         DM=-32;
/M: SY='V';  M=  -6, -20, -21, -24, -17,   6, -27, -21,  12, -13,   7,   5, -17, -21, -17, -14, -12,  -4,  13, -18,   0, -18;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30, -30, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/M: SY='G';  M=  -5,   2, -19,  -1,  -5, -17,   6,  -8, -24,  -6, -19, -14,   6, -18,  -6,  -5,   1,  -8, -19, -26, -16,  -5;
/M: SY='E';  M=  -6,   2, -24,   4,   8, -23,  -9,  -6, -23,   5, -19, -11,   2, -12,   6,   6,   3,  -1, -18, -27, -14,   6;
/I:         MD=-15;
/M: SY='S';  M=  -1,  -2, -12,  -4,   1, -19,  -8, -11, -16,  -5, -17, -11,   0,  -5,  -3,  -8,   7,   4, -11, -29, -17,  -2; D=-2;
/I:         MD=-15;
/M: SY='D';  M=  -7,   1, -22,   3,   0, -13,  -6,  -3, -13,  -6, -10,  -9,   0, -15,  -5,  -5,  -3,  -6, -12, -18,  -3,  -4; D=-2;
/I:         MD=-15;
/M: SY='D';  M=  -6,   5, -17,   6,   6, -18,  -8,  -5, -17,   2, -15, -11,   4,  -7,   2,   0,  -1,  -6, -15, -22, -13,   4; D=-2;
/I:         MD=-15;
/M:         M=  -3,  -1, -16,   0,  -2, -10,  -1,  -8, -12,  -4, -12,  -8,  -1,  -3,  -4,  -7,  -1,  -3, -10, -10,  -8,  -3; D=-2;
/I:         I=-2; MI=0; IM=0; DM=-15;
/M: SY='D';  M=  -8,   6, -25,  12,   7, -23,  -6,  -2, -25,  -5, -21, -17,   2,  -2,  -2,  -9,   4,  -1, -20, -30, -14,   2;
/M: SY='G';  M=  -2,   7, -25,   8,   4, -26,  12,  -7, -27,  -5, -22, -17,   8, -14,  -4,  -8,   2,  -9, -21, -28, -20,   0;
/M: SY='E';  M=  -6,  -1, -23,   1,   4, -18, -16, -11, -18,  -1, -15, -12,  -3,   0,  -2,  -5,  -4,  -6, -16, -24, -14,   1;
/M: SY='L';  M= -10, -25, -14, -30, -22,  10, -27, -18,  14, -21,  18,  17, -21, -25, -17, -17, -18,  -7,   9, -14,   1, -20;
/M: SY='I';  M=  -8, -27, -21, -30, -22,   3, -30, -19,  24, -22,  21,  19, -25, -25, -18, -19, -20,  -9,  20, -15,  -1, -21;
/M: SY='Q';  M=  -7,  -9, -14, -11,  -1,  -8, -19,  -7, -11,  -8,  -8,  -5,  -7, -18,   4,  -7,  -1,  -1, -11, -20,  -1,   1;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30, -30, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/M: SY='D';  M=  -8,  22, -24,  28,  11, -32,  -4,  -2, -30,   0, -25, -20,  13, -12,   4,  -5,   1,  -8, -25, -32, -18,   7;
/I:         I=-8; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='B';  M=  -7,   0, -21,   0,  -4, -16,  -4,  -8, -18,  -3, -13,  -9,  -1, -17,  -7,  -5,  -4,  -5, -13, -23,  -8,  -6;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30,-120, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/I:         MD=-29;
/M: SY='D';  M=  -9,   6, -20,   9,   3, -24,  -2,  -6, -26,   1, -22, -15,   4, -10,   1,  -1,  -2,  -9, -22, -25, -14,   1; D=-6;
/I:         I=-8; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='R';  M= -12,   2, -25,   3,   6, -21, -17,   1, -22,  11, -18, -11,   3, -15,   7,  21,  -2,  -4, -17, -25,  -9,   5; D=-6;
/I:         DM=-29;
/M: SY='W';  M=  -2, -17, -30, -18, -14, -11,  -5, -17, -18,  -9, -20, -14, -14, -11, -11, -13,  -8, -10, -17,  29,  -3, -11;
/M: SY='F';  M= -14, -25, -21, -29, -23,  30, -24,  -9,   2, -19,   3,   2, -20, -28, -21, -16, -17, -10,   2,   7,  25, -21;
/M: SY='H';  M= -20,   0, -30,   0,   0, -20, -20, 100, -30, -10, -20,   0,  10, -20,  10,   0, -10, -20, -30, -30,  20,   0;
/M: SY='Q';  M=  -6, -11, -24, -12,  -3, -17, -16, -10,  -7,  -4,  -8,  -1,  -8,  -7,   4,  -2,  -3,  -3,  -8, -24, -11,  -1;
/M:         M=  -7,  -2, -24,  -3,  -1, -11, -15,  -6, -13,   0, -13,  -8,  -1, -16,  -4,  -4,  -3,  -3, -10, -21,  -3,  -3;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30, -30, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/M: SY='L';  M=  -3, -21, -16, -24, -16,   3, -25, -14,  10, -19,  15,   8, -20, -24, -16, -17, -13,  -3,  10, -18,   3, -17;
/M: SY='G';  M=  -5,  -3, -25,  -4,  -3, -23,   2, -10, -17,  -6, -15,  -7,   0, -11,   2,  -7,  -1,  -6, -16, -26, -16,  -1;
/M: SY='P';  M= -12, -11, -28, -10,  -7,  -6, -23,  -9,  -7,  -9,  -6,  -5, -10,   3, -11,  -9, -12,  -8,  -9, -19,  -7, -10;
/M: SY='P';  M=  -2,  -6, -25,  -6,  -1, -18, -10, -12, -17,  -5, -21, -14,  -3,   8,  -5,  -9,   3,   0, -16, -20, -14,  -4;
/M:         M=  -5,  -8, -25,  -7,  -2, -13, -14, -10, -11,  -3,  -8,  -5,  -8,  -7,  -4,  -6,  -8,  -8, -10, -21,  -7,  -4;
/M: SY='E';  M=  -8,  -4, -25,  -3,   4, -15, -20, -11, -11,   1, -10,  -8,  -3,  -7,  -3,   1,  -4,  -3,  -9, -26, -12,  -1;
/I:         I=-4; MI=0; MD=-15; IM=0;
/M: SY='S';  M=  -1,  -1, -11,   0,   1, -10,  -5,  -6,  -8,  -3,  -9,  -6,  -1,   1,  -2,  -5,   3,   1,  -7, -16,  -8,  -1; D=-1;
/I:         DM=-15;
/M:         M=  -2,  -5, -16,  -6,  -3, -10,  -7,  -9,  -6,  -4,  -5,  -4,  -4,  -6,  -2,  -5,  -4,  -4,  -7, -10,  -7,  -3; D=-1;
/I:         DM=-15;
/M: SY='A';  M=   1,  -4, -19,  -5,   0, -15, -10, -10, -10,  -3,  -7,  -5,  -5,  -8,  -3,  -5,  -3,  -4,  -8, -18, -11,  -2; D=-1;
/I:         DM=-15;
/M:         M=  -2,  -2, -22,  -2,  -2, -18, -13, -12,  -6,  -6, -11,  -7,  -2,   0,  -7, -11,  -3,  -5,  -6, -25, -15,  -6; D=-1;
/I:         DM=-15;
/M: SY='P';  M=  -6,  -9, -29,  -7,   1, -20, -12, -10, -17,  -1, -18, -11,  -7,   9,  -2,  -5,  -5,  -8, -18, -16, -13,  -2;
/M: SY='D';  M= -10,   5, -27,   9,   9, -22, -11,  -8, -23,   3, -20, -15,   3,  -1,   1,   0,   0,  -4, -21, -28, -16,   5;
/M: SY='G';  M=  -5,  -4, -24,  -3,   0, -17,   1, -10, -17,  -6, -15, -10,  -1, -16,  -5,  -5,   0,  -6, -12, -25, -14,  -3;
/M: SY='B';  M=  -6,  -2, -25,  -2,  -3, -21,  -4,  -8, -16,  -3, -15,  -8,  -2, -11,  -5,  -5,  -4,  -7, -12, -24, -14,  -4;
/M: SY='W';  M= -19, -33, -39, -35, -26,  25, -24, -20, -10, -19,  -8, -10, -30, -29, -21, -17, -31, -21, -18,  86,  32, -20;
/M: SY='L';  M=  -9, -18, -16, -21, -14,  -1, -25, -12,   2, -10,   3,   2, -14, -22,  -9,  -6,  -9,  -4,   2, -16,   3, -13;
/M: SY='C';  M= -10, -20, 120, -30, -30, -20, -30, -30, -30, -30, -20, -20, -20, -40, -30, -30, -10, -10, -10, -50, -30, -30;
/M: SY='P';  M=  -8,  -8, -29,  -7,  -1, -22, -13, -12, -16,  -1, -19, -12,  -6,  13,  -4,  -3,  -4,  -4, -15, -24, -17,  -5;
/M: SY='R';  M=  -7,  -6, -21,  -8,  -2, -12, -11,  -5, -15,   1, -10,  -7,  -2, -19,  -4,   5,  -7,  -8, -12, -22,  -7,  -4;
/M: SY='C';  M= -10, -19, 115, -29, -29, -20, -30, -26, -30, -29, -20, -19, -19, -39, -29, -29, -10, -10, -11, -49, -28, -29;
/M: SY='K';  M=  -5,   0, -22,   0,   1, -19, -15,  -9, -14,   2, -11,  -5,  -1, -15,   2,   1,  -1,   1, -10, -27, -12,   1;
/M: SY='K';  M=  -8,  -3, -14,  -6,   0, -15, -18,  -9, -15,   1, -17, -10,   1,  -6,  -3,   0,  -2,  -4, -14, -27, -12,  -2;
/M: SY='K';  M=  -5,  -7,  -4,  -9,  -1, -19, -17,  -6, -20,   2, -18,  -9,  -6, -12,  -2,   2,  -2,  -5, -13, -29, -13,  -3;
/I:         E1=0; IE=-105; DE=-105;
» more

Post-processing [info]

COMPETES_HIT_WITH PS51805

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 446 in 341 different sequences
Number of true positive hits 441 in 336 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 139
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.88 %
Recall (true positives / (true positives + false negatives)) 76.03 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] window20_shuffled
Author [info] K_Hofmann
Feature key [info] ZN_FING
Feature description [info] PHD-type
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 336 sequences 

AF10_HUMAN  (P55197), AF10_MOUSE  (O54826), AF17_HUMAN  (P55198), 

AIRE_HUMAN  (O43918), AIRE_MOUSE  (Q9Z0E3), ALFIN_MEDSA (Q40359), 
ALFL1_ARATH (Q9FFF5), ALFL1_ORYSI (A2Y0Q2), ALFL1_ORYSJ (Q75IR6), 
ALFL2_ARATH (Q9SRM4), ALFL2_ORYSI (B8B8I3), ALFL2_ORYSJ (Q8H383), 
ALFL3_ARATH (Q9M2B4), ALFL3_ORYSI (B8AMA8), ALFL3_ORYSJ (Q84TV4), 
ALFL4_ARATH (O81488), ALFL4_ORYSI (A2XTW9), ALFL4_ORYSJ (Q7XUW3), 
ALFL5_ARATH (Q5XEM9), ALFL5_ORYSI (A2Y4R8), ALFL5_ORYSJ (Q60DW3), 
ALFL6_ARATH (Q8S8M9), ALFL6_ORYSI (A2WXR5), ALFL6_ORYSJ (Q7F2Z1), 
ALFL7_ARATH (Q8LA16), ALFL7_ORYSI (B8ADZ3), ALFL7_ORYSJ (Q6Z7F4), 
ALFL8_ORYSI (B8BJV8), ALFL8_ORYSJ (Q2R837), ALFL9_ORYSI (B8B8C5), 
ALFL9_ORYSJ (Q6YTY3), ATG35_KOMPG (C4QVX6), ATX1_ARATH  (Q9C5X4), 
ATX2_ARATH  (P0CB22), ATX3_ARATH  (Q9M364), ATX4_ARATH  (Q9SUE7), 
ATX5_ARATH  (Q8GZ42), ATXR5_ARATH (Q8VZJ1), ATXR5_RICCO (B9RU15), 
ATXR6_ARATH (Q9FNE9), BAZ1A_HUMAN (Q9NRL2), BAZ1A_MOUSE (O88379), 
BAZ1A_XENLA (Q8UVR5), BAZ1B_DANRE (A2BIL7), BAZ1B_HUMAN (Q9UIG0), 
BAZ1B_MOUSE (Q9Z277), BAZ1B_XENLA (A8DZJ1), BAZ2A_HUMAN (Q9UIF9), 
BAZ2A_MOUSE (Q91YE5), BAZ2A_XENLA (B7ZS37), BAZ2B_CHICK (Q9DE13), 
BAZ2B_HUMAN (Q9UIF8), BAZ2B_MOUSE (A2AUY4), BAZ2_CAEEL  (Q23590), 
BPTF_HUMAN  (Q12830), BRD1_HUMAN  (O95696), BRD1_MOUSE  (G5E8P1), 
BRDH_DROME  (Q7JVP4), BRPF1_HUMAN (P55201), BRPF1_MOUSE (B2RRD7), 
BRPF3_HUMAN (Q9ULD4), BRPF3_MOUSE (B2KF05), BYE1_CANGA  (Q6FJ00), 
BYE1_DEBHA  (Q6BNY5), BYE1_PICGU  (A5DDB7), BYE1_SCHPO  (Q9Y7V2), 
BYE1_YEAS7  (A6ZZW1), BYE1_YEAST  (P36106), C3H19_ARATH (Q9SIV5), 
C3H44_ARATH (Q9SD34), CHD3_CAEEL  (Q22516), CHD3_DROME  (O16102), 
CHD3_HUMAN  (Q12873), CHD4_HUMAN  (Q14839), CHD4_MOUSE  (Q6PDQ2), 
CHD5_HUMAN  (Q8TDI0), CHD5_MOUSE  (A2A8L1), CHD5_RAT(D3ZD32), 
CHDM_DROME  (O97159), CHR4_ARATH  (F4KBP5), CTI6_YEAST  (Q08923), 
CXXC1_BOVIN (Q5EA28), CXXC1_DROME (Q9W352), CXXC1_HUMAN (Q9P0U4), 
CXXC1_MOUSE (Q9CWW7), DIDO1_HUMAN (Q9BTC0), DIDO1_MOUSE (Q8C9B9), 
DPF1_CHICK  (P58267), DPF1_HUMAN  (Q92782), DPF1_MOUSE  (Q9QX66), 
DPF1_RAT(P56163), DPF3_CHICK  (P58270), DPF3_DANRE  (A9LMC0), 
DPF3_HUMAN  (Q92784), DPF3_MOUSE  (P58269), DPFF1_CAEEL (Q09477), 
EBS_ARATH   (F4JL28), ECM5_YEAST  (Q03214), EHD3_ORYSJ  (Q6ZJM9), 
FGT1_ARATH  (F4IF36), FXL19_HUMAN (Q6PCT2), FXL19_MOUSE (Q6PB97), 
HAT31_ARATH (Q04996), HAZ1_ORYSJ  (Q8H991), HOX1A_MAIZE (P46605), 
IDM1_ARATH  (F4IXE7), ING1_ARATH  (Q9LIQ6), ING1_DICDI  (Q54PN9), 
ING1_HUMAN  (Q9UK53), ING1_MOUSE  (Q9QXV3), ING1_SCHPO  (O42871), 
ING2_ARATH  (B3H615), ING2_HUMAN  (Q9H160), ING2_MOUSE  (Q9ESK4), 
ING2_SCHPO  (O74736), ING3_CHICK  (Q5ZK36), ING3_HUMAN  (Q9NXR8), 
ING3_MOUSE  (Q8VEK6), ING3_PONAB  (Q5RBA1), ING3_RAT(Q498T3), 
ING3_XENLA  (Q7ZX31), ING3_XENTR  (Q66KD5), ING4_BOVIN  (Q3T095), 
ING4_CHICK  (Q5ZKY4), ING4_HUMAN  (Q9UNL4), ING4_MOUSE  (Q8C0D7), 
ING5_DROME  (Q9VJY8), ING5_HUMAN  (Q8WYH8), ING5_MOUSE  (Q9D8Y8), 
INT12_BOVIN (Q32LL5), INT12_DANRE (Q6IQU7), INT12_DROME (Q9VBB3), 
INT12_HUMAN (Q96CB8), INT12_MACFA (Q8WNV2), INT12_MOUSE (Q9D168), 
INT12_PONAB (Q5RCV7), INT12_RAT   (Q68FR3), INT12_XENLA (Q6DJM6), 
INT12_XENTR (Q0V9U1), JADE1_BOVIN (Q5E9T7), JADE1_DANRE (Q803A0), 
JADE1_HUMAN (Q6IE81), JADE1_MOUSE (Q6ZPI0), JADE1_XENLA (Q6GQJ2), 
JADE2_HUMAN (Q9NQC1), JADE2_MOUSE (Q6ZQF7), JADE3_DANRE (Q7ZVP1), 
JADE3_HUMAN (Q92613), JADE3_MOUSE (Q6IE82), JADE3_XENTR (Q0P4S5), 
JHD1_ASPFU  (Q4WHB7), JHD1_CANAL  (Q5A847), JHD1_DEBHA  (Q6BXJ4), 
JHD1_EMENI  (Q5AW75), JHD1_YARLI  (Q6C423), JHD2_YEAST  (P47156), 
KAT6A_HUMAN (Q92794), KAT6A_MOUSE (Q8BZ21), KAT6A_RAT   (Q5TKR9), 
KAT6B_HUMAN (Q8WYB5), KAT6B_MACFA (Q8WML3), KAT6B_MOUSE (Q8BRB7), 
KD5BB_DANRE (Q6IQX0), KDM2A_HUMAN (Q9Y2K7), KDM2A_MOUSE (P59997), 
KDM2A_XENTR (Q5U263), KDM2B_HUMAN (Q8NHM5), KDM2B_MOUSE (Q6P1G2), 
KDM2B_XENLA (Q640I9), KDM5A_HUMAN (P29375), KDM5A_MOUSE (Q3UXZ9), 
KDM5B_CHICK (Q5F3R2), KDM5B_HUMAN (Q9UGL1), KDM5B_MOUSE (Q80Y84), 
KDM5C_CANLF (Q38JA7), KDM5C_HUMAN (P41229), KDM5C_MOUSE (P41230), 
KDM5C_PIG   (A1YVX4), KDM5D_CANLF (Q30DN6), KDM5D_HUMAN (Q9BY66), 
KDM5D_MOUSE (Q62240), KDM5D_PANTR (Q5XUN4), KDM5_CAEBR  (Q61T02), 
KDM5_CAEEL  (Q23541), KDM5_DROME  (Q9VMJ7), KDM7A_DANRE (Q5RHD1), 
KDM7A_HUMAN (Q6ZMT4), KDM7A_MOUSE (Q3UWM4), KDM7A_XENTR (Q08D35), 
KDM7B_DANRE (P0CF52), KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), 
KMT2B_HUMAN (Q9UMN6), KMT2B_MOUSE (O08550), KMT2C_HUMAN (Q8NEZ4), 
KMT2C_MOUSE (Q8BRH4), KMT2D_HUMAN (O14686), KMT2D_MOUSE (Q6PDK2), 
KMT2E_HUMAN (Q8IZD2), KMT2E_MOUSE (Q3UG20), LE418_CAEEL (G5EBZ4), 
LID2_SCHPO  (Q9HDV4), LIN49_CAEEL (Q20318), LIN59_CAEEL (O44757), 
MBD9_ARATH  (Q9SGH2), MIT1_SCHPO  (Q9P793), MLO2_SCHPO  (Q09329), 
MSC1_SCHPO  (Q9UT79), MTF2_HUMAN  (Q9Y483), MTF2_MOUSE  (Q02395), 
MTF2_PONAB  (Q5R7T9), NFXL1_ARATH (Q9SY59), NSD1_HUMAN  (Q96L73), 
NSD1_MOUSE  (O88491), NSD2_HUMAN  (O96028), NSD2_MOUSE  (Q8BVE8), 
NSD3_HUMAN  (Q9BZ95), NSD3_MOUSE  (Q6P2L6), NSD_DROME   (Q8MT36), 
NTO1_SCHPO  (O74759), NTO1_YEAST  (Q12311), NU301_CAEEL (Q6BER5), 
NU301_DROME (Q9W0T1), ORC1A_ARATH (Q710E8), ORC1B_ARATH (Q9SU24), 
ORC1_ORYSJ  (Q5SMU7), ORTH2_ARATH (Q8VYZ0), PAIP2_ARATH (F4KE59), 
PCL_DROME   (Q24459), PF21A_HUMAN (Q96BD5), PF21A_MOUSE (Q6ZPK0), 
PF21B_HUMAN (Q96EK2), PF21B_MOUSE (Q8C966), PHD1_ARATH  (B3H578), 
PHF10_BOVIN (Q2T9V9), PHF10_DANRE (Q6NWE1), PHF10_HUMAN (Q8WUB8), 
PHF10_MOUSE (Q9D8M7), PHF10_RAT   (Q4V7A6), PHF10_XENLA (Q63ZP1), 
PHF12_HUMAN (Q96QT6), PHF12_MOUSE (Q5SPL2), PHF14_DANRE (A0A286Y9D1), 
PHF14_HUMAN (O94880), PHF14_MOUSE (Q9D4H9), PHF19_MOUSE (Q9CXG9), 
PHF1_HUMAN  (O43189), PHF1_MOUSE  (Q9Z1B8), PHF1_SCHPO  (P87233), 
PHF2_DANRE  (Q6P949), PHF2_DICLA  (E6ZGB4), PHF2_HUMAN  (O75151), 
PHF2_MOUSE  (Q9WTU0), PHF2_SCHPO  (Q09908), PHF3_HUMAN  (Q92576), 
PHF8_DANRE  (P0CH95), PHF8_HUMAN  (Q9UPP1), PHF8_MOUSE  (Q80TJ7), 
PHO23_YEAST (P50947), PHRF1_HUMAN (Q9P1Y6), PHRF1_MOUSE (A6H619), 
PHRF1_RAT   (Q63625), PKL_ARATH   (Q9S775), PRH_ARATH   (P48785), 
PRH_PETCR   (P48786), PTM_ARATH   (F4JYC8), PYGO1_HUMAN (Q9Y3Y4), 
PYGO1_MOUSE (Q9D0P5), PYGO2_HUMAN (Q9BRQ0), PYGO_DROME  (Q9V9W8), 
RCO1_YEAST  (Q04779), REQUA_XENLA (Q9W638), REQUB_XENLA (Q9W636), 
REQU_CHICK  (P58268), REQU_HUMAN  (Q92785), REQU_MOUSE  (Q61103), 
RNO_DROME   (Q7YZH1), RNO_DROPS   (Q29EQ3), RSF1_HUMAN  (Q96T23), 
SAYP_DROME  (Q9VWF2), SCC2_ARATH  (A5HEI1), SET1_PLAF7  (C6KTD2), 
SET3_YEAST  (P36124), SET4_YEAST  (P42948), SHL_ARATH   (Q9FEN9), 
SNT2_YEAST  (P53127), SP110_HUMAN (Q9HB58), SP140_HUMAN (Q13342), 
SP14L_HUMAN (Q9H930), SPP1_SCHPO  (O74508), SPP1_YEAST  (Q03012), 
TAF3_CHICK  (Q5F489), TAF3_HUMAN  (Q5VWG9), TAF3_MOUSE  (Q5HZG4), 
TAF3_XENLA  (Q5EAW9), TIF1A_HUMAN (O15164), TIF1A_MOUSE (Q64127), 
TIF1B_HUMAN (Q13263), TIF1B_MOUSE (Q62318), TIF1B_RAT   (O08629), 
TRI33_DANRE (Q6E2N3), TRI33_HUMAN (Q9UPN9), TRI33_MOUSE (Q99PP7), 
TRI33_XENLA (Q56R14), TRI66_HUMAN (O15016), TRI66_MOUSE (Q924W6), 
TRX1_ORYSJ  (Q6K431), TRX_DROME   (P20659), TRX_DROVI   (Q24742), 
UBR7_DICDI  (Q54DV0), UHRF1_BOVIN (A7E320), UHRF1_DANRE (E7EZF3), 
UHRF1_HUMAN (Q96T88), UHRF1_MOUSE (Q8VDF2), UHRF1_RAT   (Q7TPK1), 
UHRF1_XENLA (B6CHA3), UHRF1_XENTR (F6UA42), UHRF2_HUMAN (Q96PU4), 
UHRF2_MOUSE (Q7TMI3), Y3228_ARATH (Q5PNS0), Y8158_DICDI (Q55FD6), 
YA27_SCHPO  (Q09698), YAC5_SCHPO  (Q09819), YNG2_CANAL  (Q5AHB8), 
YNG2_CANGA  (Q6FSB1), YNG2_DEBHA  (Q6BNL6), YNG2_EREGS  (Q757W2), 
YNG2_KLULA  (Q6CXN0), YNG2_YARLI  (Q6C5V7), YNG2_YEAST  (P38806), 
YQF7_SCHPO  (O94400), ZFP1_CAEEL  (P34447), ZMY11_HUMAN (Q15326), 
ZMY11_MOUSE (Q8R5C8), ZMYD8_DROME (Q7KRS9), ZMYD8_HUMAN (Q9ULU4)
» more

UniProtKB/Swiss-Prot
False negative sequences		 139 sequences 

AIPP2_ARATH (F4IYH6), ARID4_ARATH (Q6NQ79), ASH1L_HUMAN (Q9NR48), 

ASH1L_MOUSE (Q99MY8), ASH1_DROME  (Q9VW15), ASH2L_HUMAN (Q9UBL3), 
ASH2L_MOUSE (Q91X20), ASH2_CAEEL  (G5EFZ3), ASH2_DROME  (Q94545), 
ASH2_SCHPO  (O60070), ASHR3_ARATH (Q949T8), ASXL1_HUMAN (Q8IXJ9), 
ASXL1_MOUSE (P59598), ASXL2_CHICK (Q5ZM88), ASXL2_HUMAN (Q76L83), 
ASXL2_MOUSE (Q8BZ32), ASXL3_HUMAN (Q9C0F0), ASXL3_MOUSE (Q8C4A5), 
ASX_DROME   (Q9V727), BYE1_YARLI  (Q6C0K9), CBFA_DICDI  (O97101), 
CTI6_SCHPO  (Q1MTR4), EBSL_ARATH  (F4JGB7), EDM2_ARATH  (F4K3G5), 
G2E3_CHICK  (Q5F4A1), G2E3_HUMAN  (Q7L622), G2E3_MACFA  (Q4R9C4), 
G2E3_MOUSE  (Q5RJY2), HAC12_ARATH (Q9FWQ5), HAC1_ARATH  (Q9C5X9), 
HAC2_ARATH  (Q9FYH1), HAC4_ARATH  (Q9LG11), HAC5_ARATH  (Q9LE42), 
HACL1_ORYSJ (Q6YXY2), HACL2_ORYSJ (Q5Z8V7), HACL3_ORYSJ (Q9XHY7), 
HOP1_SCHPO  (Q9P7P2), JHD1_CRYNB  (P0CO41), JHD1_CRYNJ  (P0CO40), 
JHD1_EREGS  (Q75AL5), JHD1_KLULA  (Q6CIC9), JHD1_MYCMD  (Q4P5U1), 
JHD1_YEAST  (P40034), JMJ17_ARATH (F4I240), JMJ24_ARATH (F4HZD1), 
KDM4A_HUMAN (O75164), KDM4A_MOUSE (Q8BW72), KDM4A_PONAB (Q5RD88), 
KDM4B_HUMAN (O94953), KDM4B_MOUSE (Q91VY5), KDM4C_HUMAN (Q9H3R0), 
KDM4C_MOUSE (Q8VCD7), KDM7_CAEEL  (Q9GYI0), LSY13_CAEEL (A3QMD7), 
MES4_CAEEL  (Q9NH52), MMD1_ARATH  (Q7X6Y7), MS1_ARATH   (Q9FMS5), 
OBE1_ARATH  (Q9S736), OBE2_ARATH  (Q9LUB7), OBE3_ARATH  (Q94B71), 
OBE4_ARATH  (Q84TI3), ORTH1_ARATH (Q9FKA7), ORTH3_ARATH (Q9FVS2), 
ORTH4_ARATH (Q9C8E1), ORTH5_ARATH (Q680I0), P20L1_HUMAN (A8MW92), 
P20L1_MOUSE (Q8CCJ9), P20L1_RAT   (Q4V9H5), PF23A_DANRE (Q5BJ10), 
PF23A_XENLA (Q5HZN9), PF23B_DANRE (Q7SXB5), PF23B_XENLA (Q0IHB0), 
PH11A_MOUSE (Q8BVM9), PH11L_RAT   (Q5I0J8), PHD4_ARATH  (Q9FNQ4), 
PHD5_ARATH  (Q9FNQ5), PHD6_ARATH  (F4K200), PHF11_BOVIN (Q2HJ93), 
PHF11_HUMAN (Q9UIL8), PHF11_MOUSE (A6H5X4), PHF11_RAT   (Q5I0E2), 
PHF13_HUMAN (Q86YI8), PHF13_MOUSE (Q8K2W6), PHF19_HUMAN (Q5T6S3), 
PHF20_HUMAN (Q9BVI0), PHF20_MOUSE (Q8BLG0), PHF23_BOVIN (A5D962), 
PHF23_HUMAN (Q9BUL5), PHF23_MOUSE (Q8BSN5), PHF23_RAT   (Q6AY75), 
PHF23_XENTR (Q5U5E5), PHF24_HUMAN (Q9UPV7), PHF24_MOUSE (Q80TL4), 
PHF24_PONAB (Q5R4R7), PHF6_BOVIN  (Q08DR0), PHF6_HUMAN  (Q8IWS0), 
PHF6_MOUSE  (Q9D4J7), PHF6_PONAB  (Q5R5Z2), PHF7_HUMAN  (Q9BWX1), 
PHF7_MOUSE  (Q9DAG9), PHF7_RAT(Q6AXW4), PTC1_ORYSJ  (Q67V61), 
PVIP_NICBE  (Q84N38), PVIP_PEA(Q84N37), RAG2_CHICK  (P25022), 
RAG2_DANRE  (O13034), RAG2_HUMAN  (P55895), RAG2_MOUSE  (P21784), 
RAG2_ONCMY  (Q91193), RAG2_RABIT  (P34089), RAG2_XENLA  (Q91830), 
RAI1_HUMAN  (Q7Z5J4), RAI1_MOUSE  (Q61818), SET26_CAEEL (Q9U263), 
SET3_SCHPO  (Q10362), SET9_CAEEL  (O44498), SETVS_PLAF7 (Q8IE95), 
SHPRH_HUMAN (Q149N8), SHPRH_MOUSE (Q7TPQ3), SIZ1_ARATH  (Q680Q4), 
SIZ1_ORYSJ  (Q6L4L4), SIZ2_ORYSJ  (Q6ASW7), SNT2_SCHPO  (Q10077), 
TCF19_HUMAN (Q9Y242), TCF19_MACMU (Q5TM48), TCF19_PANTR (Q7YR48), 
TCF19_PIG   (Q9TSV4), TCF20_HUMAN (Q9UGU0), TCF20_MOUSE (Q9EPQ8), 
TTA1_ORYSJ  (Q10PC5), UBR7_HUMAN  (Q8N806), UBR7_MOUSE  (Q8BU04), 
VIL1_ARATH  (Q9LHF5), VIL2_ARATH  (Q9SUM4), VIL3_ARATH  (Q5BPT4), 
VIN3_ARATH  (Q9FIE3), Y1342_ARATH (Q9C810), Y2181_ARATH (Q9ZUA9), 
YNG1_YEAST  (Q08465)
» more

UniProtKB/Swiss-Prot
False positive sequences		 5 sequences 

FAP1H_SCHPO (O74853), NFX1_BOVIN  (A6QLA0), NFX1_DICDI  (Q54BK0), 

NFX1_HUMAN  (Q12986), NFX1_MOUSE  (B1AY10)
» more

PDB
[Detailed view]		 323 PDB

1F62; 1FP0; 1MM2; 1MM3; 1WE9; 1WEE; 1WEM; 1WEN; 1WEP; 1WES; 1WEU; 1WEV; 1WEW; 1WIL; 1X4I; 1XWH; 2DX8; 2E6R; 2E6S; 2F6J; 2F6N; 2FSA; 2FUI; 2FUU; 2G6Q; 2JMI; 2JMJ; 2K16; 2K17; 2K1J; 2KE1; 2KFT; 2KGG; 2KGI; 2KU3; 2KU7; 2KWJ; 2KWK; 2KWN; 2KWO; 2KYU; 2L43; 2L5U; 2L75; 2LGG; 2LGK; 2LGL; 2LN0; 2LRI; 2LV9; 2M1R; 2M3H; 2M85; 2MA5; 2MD7; 2MD8; 2MIQ; 2MNY; 2MNZ; 2MUM; 2NAA; 2PNX; 2PUY; 2QIC; 2RI7; 2RO1; 2RSD; 2VNF; 2VP7; 2VPB; 2VPD; 2VPE; 2VPG; 2XB1; 2YQL; 2YSM; 2YT5; 2YYR; 3ASK; 3ASL; 3C6W; 3GL6; 3KQI; 3KV4; 3KV5; 3KV6; 3LQH; 3LQI; 3LQJ; 3N9L; 3N9M; 3N9N; 3N9O; 3N9P; 3N9Q; 3O33; 3O34; 3O35; 3O36; 3O37; 3O70; 3O7A; 3PUQ; 3PUR; 3QZV; 3SHB; 3SOU; 3SOW; 3SOX; 3T6R; 3U5M; 3U5N; 3U5O; 3U5P; 3V43; 3ZPV; 3ZVY; 3ZVZ; 4BBQ; 4BXZ; 4COS; 4GND; 4GNE; 4GNF; 4GNG; 4GY5; 4L58; 4L7X; 4LJN; 4LK9; 4LKA; 4LLB; 4O64; 4Q6F; 4QF2; 4QF3; 4TVR; 4UP0; 4UP5; 4YAB; 4YAD; 4YAT; 4YAX; 4YBM; 4YBS; 4YBT; 4YC9; 4ZQL; 5B73; 5B75; 5B76; 5B77; 5B78; 5B79; 5C11; 5C13; 5CEH; 5DAG; 5DAH; 5ERC; 5H1T; 5H1U; 5H1V; 5HH7; 5I3L; 5K4L; 5MR8; 5OQD; 5SZB; 5SZC; 5T8R; 5TAB; 5TBN; 5TDR; 5TDW; 5U2J; 5V9P; 5V9T; 5VDC; 5WXG; 5WXH; 5XFN; 5XFO; 5XFP; 5XFQ; 5XFR; 5XHT; 5XMY; 5Y1Z; 5Y20; 5YC3; 5YC4; 5Z8L; 5Z8N; 6ASB; 6AZE; 6FAP; 6FHQ; 6FHU; 6FI0; 6FI1; 6FKP; 6G8R; 6GUU; 6IET; 6IEU; 6IIW; 6J2P; 6LQE; 6LQF; 6LSB; 6LTH; 6LTJ; 6MLC; 6MZD; 6MZL; 6O7G; 6OIE; 6Q3M; 6RYR; 6RYU; 6U04; 6VEN; 6VFO; 6WXK; 7CRO; 7CRP; 7CRQ; 7CRR; 7CWH; 7D86; 7D87; 7D8A; 7DUF; 7EBJ; 7EBK; 7EDX; 7EG7; 7EG8; 7EG9; 7EGA; 7EGB; 7EGC; 7EGD; 7EGE; 7EGF; 7EGI; 7EGJ; 7ENA; 7ENC; 7KLO; 7KLR; 7M10; 7MJU; 7UV9; 7VDV; 7VVU; 7VVZ; 7XGA; 7Y0I; 7Y8R; 7YI0; 7YI2; 7YI3; 7YI4; 7YI5; 7ZDD; 7ZEY; 7ZEZ; 7ZMX; 8BD8; 8BD9; 8BDY; 8BPA; 8BPB; 8BPC; 8C60; 8F8Y; 8F8Z; 8GA8; 8GDX; 8GE0; 8GXQ; 8GXS; 8HPO; 8HXX; 8HXY; 8HY0; 8I02; 8I03; 8I3F; 8IFG; 8IHN; 8IHT; 8JHO; 8KC7; 8KD2; 8KD3; 8KD4; 8KD5; 8KD6; 8KD7; 8TOF; 8U2Y; 8W9C; 8W9D; 8W9E; 8W9F; 8WAK; 8WAL; 8WAN; 8WAO; 8WAP; 8WAQ; 8WAR; 8WAS; 8WMS; 8XV4; 8XV6; 8XV7; 8XV8; 9ATN; 9C0O
» more