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| Entry: PS50135 |
General information about the entry
| Entry name [info] | ZF_ZZ_2 |
| Accession [info] | PS50135 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
02-JUN-2021 DATA UPDATE; 02-JUN-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50135 |
| Associated ProRule [info] | PRU00228 |
Name and characterization of the entry
| Description [info] | Zinc finger ZZ-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=57; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=52; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3384571; R2=0.0091303; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1332; N_SCORE=14.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=456; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-26; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='H'; M= -6, -13, -58, -21, 6, -15, 97, -70, 17, -8, -57, -3, -17, -26, 0, 31, -12, -68, -80, -30; /M: SY='H'; M= -47, -1, 27, -12, 20, -16, 66, -55, 4, 8, 33, -33, 5, -27, -40, 0, -38, 15, 27, -52; /M: SY='Q'; M= -8, -75, 12, 18, -75, 25, 5, -68, 21, -26, -62, 8, 11, 56, -34, 13, -56, -4, -78, -33; /M: SY='Y'; M= -3, -73, -69, -66, 19, -72, 10, 18, -1, -37, -20, -31, 20, -25, -64, -4, 15, 34, -59, 70; /M: SY='H'; M= -10, 32, -60, -16, -31, -49, 52, 3, 16, -63, -10, -16, 5, 15, 11, 28, 32, -10, -78, 0; /M: SY='C'; M= -61, 152, -80, -80, -71, -76, 12, -79, -76, -69, -68, -66, -91, -82, -82, -64, -61, -66,-101, -79; /M: SY='D'; M= -30, 18, 70, -48, -20, -60, 14, -72, -10, -75, -69, 68, -69, -54, -18, 25, 18, -26, -90, -65; /M: SY='H'; M= -8, -8, -61, -28, -57, 26, 69, 12, -18, -38, -56, 25, -71, -58, -32, -14, 23, 0, -70, 52; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='C'; M= -30, 52, -17, -36, -72, 20, 31, -71, 27, 1, -60, 5, -70, 44, 19, 35, -36, -69, -80, -64; /M: SY='Q'; M= 3, 10, -37, 0, -44, 0, 16, -22, 30, -29, -11, -15, -67, 49, -10, 11, 24, 7, -79, -63; /M: SY='D'; M= -28, 29, 43, 23, 19, -47, 38, -20, -58, 1, -59, 21, 39, -18, -12, -28, -40, -36, -74, 14; /I: I=-45; MD=-115; /M: SY='P'; M= -54, 40, -82, -75, -79, -45, -81, 4, -20, -25, 32, -27, 73, -77, -81, -6, -67, 3, -92, -81; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='I'; M= -13, -72, -72, 4, 19, -77, -73, 69, -69, 9, 4, -68, -21, -66, -73, 14, -1, 22, -73, -55; /M: SY='T'; M= -43, -70, -59, -29, -48, -25, -23, 15, -22, -38, 14, 39, -12, 17, 15, 18, 56, 16, -82, -63; /I: I=-38; MD=-97; /M: SY='G'; M= -44, -83, -65, 9, -86, 77, -73, -92, -32, -66, -79, -2, -75, -65, -9, -2, -37, -86, 7, -80; D=-38; /I: I=-38; MI=-97; MD=-97; IM=-97; DM=-97; /M: SY='F'; M= -64, -76, -21, -65, 32, -76, -14, 19, -7, 8, -7, 5, 25, -2, 15, 2, -6, 22, -75, -56; D=-38; /I: I=-38; DM=-97; /M: SY='R'; M= -67, -8, -66, -57, -63, -17, 13, -80, -34, -73, -64, -59, -77, -46, 100, -20, -66, -76, 28, 46; D=-38; /I: I=-38; DM=-97; /M: SY='W'; M= -71, -83, -83, -78, 44, -78, -58, 14, -71, -42, -7, -79, -81, -69, -70, -72, -70, -22, 126, 98; /M: SY='H'; M= -64, -79, -58, -49, -34, -72, 86, -39, 53, -68, -58, -8, -29, 45, 56, -40, -61, 2, -80, -55; /M: SY='C'; M= -57, 143, -72, -75, -72, -69, -74, -77, -71, -71, -69, 6, -85, -74, -77, 35, -55, -66, -97, -78; /M: SY='Q'; M= 14, -70, -59, 4, -64, -66, -21, -56, -6, 36, -51, 15, -27, 52, -17, 20, 25, -25, -77, -62; /M: SY='K'; M= -58, -74, -12, 35, -69, -73, -23, -3, 49, -22, -35, -14, -67, 37, -2, -6, -2, 38, -79, -64; /M: SY='C'; M= -8, 142, -72, -33, -73, -72, -1, -77, -5, -70, -67, -14, -84, 3, -71, -60, -60, -67, -95, -77; /M: SY='P'; M= -16, -77, 17, 11, 28, -7, 1, -38, 25, -18, -24, -58, 56, 24, -10, -12, -22, -32, -71, -14; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='D'; M= -63, -76, 92, -10, -83, -29, -24, -82, 4, -83, -76, 68, -13, -51, -57, 6, -53, -80, -95, -70; /M: SY='Y'; M= -70, -27, -77, -77, 78, -80, -52, 9, -71, -19, -9, -73, -82, -71, -69, -68, -11, -16, -39, 100; /M: SY='D'; M= -38, -78, 98, -7, -13, -65, 25, -77, -53, -26, -70, 29, -69, 27, -31, -55, -58, -76, -88, -13; /M: SY='L'; M= -42, -70, -84, -78, -2, -86, -73, 43, -77, 74, -8, -81, -81, -72, -76, -74, -61, 21, -72, -53; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='Q'; M= -34, -2, 33, 26, -44, -68, -59, 10, -21, -18, -59, 2, 7, 56, -29, 20, 19, -14, -79, -18; /M: SY='S'; M= -9, -73, 35, 18, -76, 3, -58, -17, 7, -54, -27, 18, -3, 30, 1, 36, 15, -32, -82, -68; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='Y'; M= -71, -76, -73, -3, 90, -79, -15, -54, -20, -38, -19, -71, -81, -68, -65, -34, -65, -43, -39, 94; /M: SY='W'; M= 12, -72, 12, 17, 0, -39, 34, -66, -3, -5, -10, 8, -7, 25, -58, 35, 19, -64, 36, -58; /M: SY='T'; M= 23, -4, -6, 1, -41, -5, 22, -46, 14, -68, -62, -23, -67, 27, 18, 25, 32, 4, -80, -64; /I: I=-21; MD=-53; /M: SY='G'; M= -33, -7, -3, 20, -80, 70, -17, -80, 3, -40, -70, 25, 12, -9, -64, -53, -15, -56, -80, -74; D=-21; /I: I=-21; MD=-53; /M: SY='R'; M= 11, -7, -28, -24, -18, -38, 38, -47, 28, -13, -61, -37, -74, 38, 52, -16, -63, -24, -77, -7; D=-21; /I: I=-21; MD=-53; /M: SY='F'; M= -7, -26, -67, 34, 42, -59, -5, -46, -11, -73, -72, 5, -81, -33, -18, -42, 15, -45, -76, 20; D=-21; /I: I=-21; MD=-53; /M: SY='S'; M= -10, -86, -35, -81, -76, -14, -82, 10, -51, -1, -68, -75, -35, -77, -12, 25, 9, -11, -91, -11; D=-21; /I: I=-21; MD=-53; /M: SY='K'; M= -40, -94, -19, -4, -44, 11, -81, -58, 19, -91, -85, -23, -2, -43, -20, -14, 3, -29, -95, -25; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='N'; M= -43, -85, -7, -65, -87, 23, -22, -30, 2, -86, -77, 38, 27, -35, 33, 22, -38, -81, -90, -79; D=-21; /I: I=-21; DM=-53; /M: SY='H'; M= -67, -78, -55, -56, 3, -70, 140, -77, -59, -63, 34, -10, -70, -49, -54, -15, -65, -78, -93, -38; /M: SY='P'; M= -52, -77, 16, -27, -77, -13, 20, -73, 28, -22, -64, 2, 65, 26, 22, 30, -6, -72, -80, -67; /I: I=-31; MD=-79; /M: SY='S'; M= -40, 29, -19, -4, -75, -54, -66, -46, -7, -6, -16, 36, 22, -60, -1, 36, 24, -21, -89, -73; D=-31; /I: I=-31; MD=-79; /M: SY='N'; M= -63, -88, 39, -5, -85, -77, 32, -89, -66, -89, -82, 43, -32, -13, -17, 5, 22, -87, 33, -15; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='H'; M= -13, -78, -56, -56, -63, -43, 137, -78, -59, -25, -54, -46, -70, -50, -55, 4, -63, -77, -89, 18; /M: SY='P'; M= 5, -76, 54, 4, -34, -24, -62, -12, 0, -50, -65, -35, 56, 19, -17, 6, 16, -25, -81, -68; /M: SY='M'; M= -67, -73, -81, -76, 64, -81, -57, 6, -41, 24, 84, -74, -79, -68, -68, -71, -63, -5, -50, 73; /M: SY='Q'; M= -46, -74, -47, 29, -24, -47, 13, 16, 11, 10, 14, -60, -29, 44, 5, -24, 18, 9, -73, 6; /M: SY='R'; M= -16, 26, -57, 44, -27, -73, -61, 11, 20, -15, -58, -15, 26, -26, 51, -16, -18, -11, -77, -65; /M: SY='M'; M= -48, -74, -77, -47, -4, -81, 33, 47, -66, 3, 74, -71, -76, -64, 5, -68, -60, 40, 3, 48; /M: SY='D'; M= -7, 48, 49, 42, -72, -24, -59, -51, -15, -36, -67, -26, 39, -20, 0, -2, 13, -69, -79, 8; /M: SY='T'; M= -26, -70, -32, -11, -31, -10, -63, 31, -1, -37, -8, 15, -1, -27, 7, 44, 44, -23, -79, -64; /M: SY='P'; M= -1, -75, 14, -6, -69, -3, -61, -12, -27, -3, 7, 33, 54, 24, -8, -5, -17, -16, 24, -38; /M: SY='T'; M= -33, -12, 5, -5, -2, 10, -8, -2, -2, -20, -4, 39, 2, -32, -14, -3, 39, 2, -79, -31; /M: SY='D'; M= -36, -72, 40, -40, 33, -1, -62, -7, -14, -33, -60, -14, 6, 10, -33, 32, 27, 3, -72, 4; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 101 in 92 different sequences |
| Number of true positive hits | 101 in 92 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 3 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 97.12 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Feature key [info] | ZN_FING |
| Feature description [info] | ZZ-type |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
92 sequences
ADA2_CANAL (Q59WH0 ), ADA2_SCHPO (Q9P7J7 ), ADA2_YEAST (Q02336 ), BIG_ARATH (Q9SRU2 ), BIG_ORYSJ (B9G2A8 ), CBP1_CAEEL (P34545 ), CBP_HUMAN (Q92793 ), CBP_MOUSE (P45481 ), CBP_RAT (Q6JHU9 ), DMDA_DROME (Q9VDW6 ), DMDB_DROME (Q9VDW3 ), DMDD_DROME (Q0KI50 ), DMDE_DROME (Q7YU29 ), DMD_CAEEL (Q9TW65 ), DMD_CANLF (O97592 ), DMD_CHICK (P11533 ), DMD_HUMAN (P11532 ), DMD_MOUSE (P11531 ), DMD_PIG (Q5GN48 ), DMD_RAT (P11530 ), DRP2_HUMAN (Q13474 ), DRP2_MOUSE (Q05AA6 ), DRP2_RAT (Q9EPA0 ), DTN1_CAEEL (Q9Y048 ), DTNA_HUMAN (Q9Y4J8 ), DTNA_MOUSE (Q9D2N4 ), DTNB_HUMAN (O60941 ), DTNB_MOUSE (O70585 ), DTNB_RAT (P84060 ), DYTN_DANRE (A2CI97 ), DYTN_HUMAN (A2CJ06 ), DYTN_MOUSE (A2CI98 ), EP300_HUMAN (Q09472 ), EP300_MOUSE (B2RWS6 ), HAC12_ARATH (Q9FWQ5 ), HAC1_ARATH (Q9C5X9 ), HAC2_ARATH (Q9FYH1 ), HAC4_ARATH (Q9LG11 ), HAC5_ARATH (Q9LE42 ), HACL1_ORYSJ (Q6YXY2 ), HACL2_ORYSJ (Q5Z8V7 ), HACL3_ORYSJ (Q9XHY7 ), HERC2_HUMAN (O95714 ), HERC2_MOUSE (Q4U2R1 ), JOKA2_SOLTU (M1BJF6 ), KCMF1_BOVIN (Q1LZE1 ), KCMF1_DANRE (Q7T321 ), KCMF1_DROME (Q95RX5 ), KCMF1_HUMAN (Q9P0J7 ), KCMF1_MOUSE (Q80UY2 ), KCMF1_XENLA (Q6GPB6 ), MIB1_DANRE (Q804S5 ), MIB1_HUMAN (Q86YT6 ), MIB1_MOUSE (Q80SY4 ), MIB1_XENLA (Q6GNY1 ), MIB2_CHICK (Q5ZIJ9 ), MIB2_HUMAN (Q96AX9 ), MIB2_MOUSE (Q8R516 ), MIB2_RAT (Q68LP1 ), MIB_DROME (Q9VUX2 ), NBR1_ARATH (Q9SB64 ), NBR1_HUMAN (Q14596 ), NBR1_MOUSE (P97432 ), NBR1_PONAB (Q5RC94 ), NBR1_RAT (Q501R9 ), PRT1_ARATH (Q8LBL5 ), REF2P_DROME (P14199 ), REF2P_DROSI (Q24629 ), SQSTM_HUMAN (Q13501 ), SQSTM_MOUSE (Q64337 ), SQSTM_PONAB (Q5RBA5 ), SQSTM_RAT (O08623 ), SWI3D_ARATH (Q8VY05 ), TAD2A_ARATH (Q9SFD5 ), TAD2B_ARATH (Q9ATB4 ), TAD2B_DANRE (Q503N9 ), TAD2B_DROME (Q8I8V0 ), TAD2B_HUMAN (Q86TJ2 ), TAD2B_PONAB (Q5RBN9 ), TAD2B_XENLA (Q6NRB5 ), TADA2_ORYSJ (Q75LL6 ), UTRN_HUMAN (P46939 ), UTRN_RAT (G3V7L1 ), Y3893_DICDI (Q54QG5 ), YN8B_SCHPO (Q9P792 ), YOY6_CAEEL (P34664 ), ZSWM2_HUMAN (Q8NEG5 ), ZSWM2_MOUSE (Q9D9X6 ), ZZEF1_HUMAN (O43149 ), ZZEF1_MOUSE (Q5SSH7 ), ZZZ3_HUMAN (Q8IYH5 ), ZZZ3_MOUSE (Q6KAQ7 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
3 sequences
RSC8_YEAST (P43609 ), SSR2_SCHPO (O14470 ), TAD2A_DROME (Q7KSD8 ) |
| PDB [Detailed view] |
34 PDB
1TOT; 2DIP; 2E5R; 2FC7; 2N1A; 4XI6; 4XI7; 4XIB; 5U7G; 5YP7; 5YP8; 5YPA; 5YPB; 5YPC; 5YPE; 5YPF; 5YPG; 5YPH; 6CW2; 6CW3; 6DS6; 6E83; 6E86; 6K15; 6KHZ; 6KW3; 6KW4; 6KW5; 6MJ7; 6TDA; 6V8O; 6V92; 6WW3; 6WW4 » more |
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