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| Entry: PS50135 |
General information about the entry
| Entry name [info] | ZF_ZZ_2 |
| Accession [info] | PS50135 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 08-MAY-2019 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50135 |
| Associated ProRule [info] | PRU00228 |
Name and characterization of the entry
| Description [info] | Zinc finger ZZ-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=48; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=44; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4852999; R2=0.0112511; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1673.0373535; R2=5.6606874; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=624; H_SCORE=5205; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=446; H_SCORE=4198; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='V'; M= -2,-14,-21,-16,-15, -1,-16,-19, 0,-11, -4, 1,-13,-12,-17,-14, -8, -4, 5,-21, -7,-16; /M: SY='H'; M=-11, -7,-25, -8, -5,-11,-11, 25,-22, 0,-19, -7, 1,-18, -2, 4, -3, -9,-16,-24, 1, -5; /M: SY='H'; M=-16, -1,-30, -2, -1,-12,-18, 29,-22, -2,-17, -4, 2,-12, 1, 1,-11,-14,-23,-13, 4, -2; /M: SY='N'; M= -6, 4,-25, 4, 5,-26, -3, 0,-22, -1,-23,-13, 6, -4, 4, -5, 3, -6,-20,-29,-17, 4; /M: SY='V'; M= 1,-20,-19,-26,-23, 6,-25,-16, 16,-18, 4, 4,-15,-24,-20,-19,-10, -5, 17,-14, 8,-23; /M: SY='E'; M= -4, -5,-14, -6, 4,-21,-18, -4,-18, 2,-18,-11, -3, -5, 2, 0, 3, 3,-14,-29,-13, 2; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='B'; M= -3, 33,-21, 31, 6,-27, -4, 0,-26, -2,-27,-22, 30,-14, -1, -8, 9, -2,-24,-37,-20, 2; /M: SY='G'; M= -4, -3,-26, -4, -7,-18, 8,-12,-16, -8,-17,-11, 0,-17,-10,-12, -2, -9,-12,-21,-10, -9; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /I: I=-6; MI=-29; MD=-29; IM=-29; DM=-29; /M: SY='G'; M= 0, -4,-15, -4, -2,-16, 10, -6,-18, 4,-15, -8, 0, -9, 1, 4, 1, -5,-13,-13,-11, -1; D=-5; /I: DM=-25; /M: M= -2, -8, -5,-11, -4, -9, -9,-11, -8,-11, -4, -2, -6,-17, -5,-11, -3, -5, -6,-22,-11, -4; D=-5; /I: DM=-25; /M: M= -5, -5, -5, -5, -2,-17,-10,-14,-18, -2, -9, -9, -6,-17, -7, -3, -5, -2,-12,-25,-14, -5; D=-5; /I: DM=-25; /M: SY='P'; M= -5,-13,-14,-11, -8,-18,-19, -9, -9,-10,-16, -9,-11, 15,-10,-11, -4, -5, -7,-29,-16,-12; D=-5; /I: DM=-25; /M: SY='I'; M=-10,-22,-22,-29,-22, 11,-29,-13, 19,-23, 11, 13,-15,-22,-18,-20,-12, -4, 13,-18, 4,-21; /M: SY='I'; M= -2,-16,-20,-21,-16, -8,-23,-18, 14,-16, 3, 8,-12,-13,-11,-16, -5, 0, 13,-27,-10,-15; /M: SY='G'; M= -3, -9,-31, -8,-11,-29, 50,-17,-37,-13,-29,-19, -2,-10,-14,-12, -2,-18,-29,-22,-28,-13; /M: SY='F'; M= -3,-15,-17,-20,-16, 13,-19,-13, -3,-18, -3, -5, -9,-13,-19,-15, 0, 4, 1,-19, -1,-17; /M: SY='R'; M=-18,-12,-28,-13, -4,-17,-21, -2,-21, 23,-14, -3, -4,-21, 6, 56,-11, -9,-12,-21, -9, -3; /M: SY='Y'; M=-19,-26,-29,-29,-25, 38,-28, -2, -1,-17, 0, -2,-24,-30,-21,-15,-22,-12, -6, 39, 53,-23; /M: SY='R'; M=-11, -5,-26, -5, 1,-22,-19, 9,-23, 19,-21, -7, 0,-16, 8, 25, -3, -4,-15,-24, -6, 3; /M: SY='C'; M= -6,-16, 96,-24,-24,-20,-24,-26,-28,-26,-22,-20,-14,-34,-24,-26, -1, -4,-10,-48,-28,-24; /I: I=-6; MI=-10; IM=-10; DM=-15; MD=-15; /M: SY='Q'; M= -2, -7,-20,-10, -1,-14,-18,-10, -5, -6, 0, -1, -5,-17, 3, -6, -2, 0, -6,-26,-11, 1; /M: SY='V'; M= -7,-15,-23,-16, -6,-14,-25,-13, 3, -2, 0, 3,-12,-19, 1, 1, -8, -6, 4,-24, -8, -4; /M: SY='C'; M=-11,-16, 92,-24,-24,-21,-28,-14,-30,-22,-21,-17,-15,-36,-23,-22,-10,-11,-13,-46,-23,-24; /M: SY='P'; M= -7, -5,-27, 0, 10,-14,-18, -3,-19, -8,-19,-14, -6, 14, -4,-12, -1, -6,-18,-27,-13, 2; /M: SY='D'; M=-13, 40,-24, 41, 13,-30, -6, 4,-30, 0,-29,-24, 35,-14, 1, -5, 7, -4,-29,-39,-20, 7; /M: SY='Y'; M=-20,-19,-29,-21,-19, 32,-29, 22, -3,-12, -1, 0,-17,-29,-12,-10,-19,-11,-11, 23, 69,-19; /M: SY='D'; M=-17, 36,-29, 46, 13,-35, -5, 9,-35, -1,-28,-23, 21,-13, 5, -7, 0,-10,-30,-36,-16, 9; /M: SY='L'; M= -9,-30,-22,-33,-23, 7,-33,-23, 28,-29, 39, 19,-27,-27,-21,-23,-26, -9, 18,-21, -1,-23; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='E'; M= 1, 1,-22, 1, 6,-19,-17, -9,-11, -5,-12, -8, -3,-12, 6, -9, 2, -1, -9,-25,-12, 6; /M: SY='S'; M= -3, -3,-21, -5, -6,-19, -9,-15,-10, -5,-18,-11, 0, -6, -7, -9, 8, 5, -6,-30,-16, -8; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='Y'; M=-16,-14,-27,-14, 1, 25,-26, -1,-11, -6, -5, -6,-13,-20,-10, -7,-14,-10,-13, 3, 29, -5; /M: SY='N'; M= -3, 0,-21, -5, -8, -7, -8,-11,-13,-11,-16,-13, 7, -8,-10, -9, 6, 1,-12,-27,-12, -9; /M: SY='T'; M= 2, -4,-19, -8, -4,-20, -9, -6,-17, 2,-18, -9, -1,-13, 0, -2, 8, 9, -8,-27,-12, -2; /M: SY='G'; M= -6, -6,-27, -7, -5,-25, 8, -2,-25, 2,-22, -7, -2, -7, 0, -2, -2, -7,-20,-24,-14, -3; /M: SY='R'; M= -9, -6,-25, -8, -4,-15,-11, -6,-13, 4,-12, -6, 1,-18, 2, 7, -3, -6,-13,-21, -5, -2; /I: I=-6; MI=-29; MD=-29; IM=-29; /M: SY='Y'; M= -4, -3,-12, -5, -8, -3, 3, -3, -7, -7, -8, -5, 1,-12, -7, -7, -1, 0, -6, -6, 4, -8; D=-6; /I: DM=-29; /M: SY='H'; M= 0, 0,-18, -2, 5,-17, -8, 22,-19, -6,-14, -7, 2,-10, 2, -6, 2, 0,-15,-22, -4, 2; D=-6; /I: DM=-29; /M: SY='H'; M=-12, 2,-29, 6, 4,-24, -4, 12,-29, 2,-24,-14, 2, -5, 0, 1, -4, -9,-25,-24, -7, 0; /M: SY='E'; M= -8, 6,-28, 12, 20,-29, -3, -8,-29, 3,-24,-18, 1, 1, 5, -5, 1, -4,-25,-28,-20, 12; /M: SY='H'; M=-17, 0,-29, -2, 1,-16,-21, 63,-20, -8,-16, -1, 8,-19, 9, -3, -9,-15,-23,-24, 16, 1; /M: SY='E'; M= -7, -2,-24, -3, 9,-20,-19, 6,-20, 9,-14, -8, -1,-12, 4, 8, -2, 1,-16,-26, -7, 5; /M: SY='M'; M=-11,-20,-24,-24,-14, -7,-23, -9, 8, -4, 9, 26,-18,-12, -5, 1,-17, -9, 4,-22, -6,-11; /M: SY='L'; M= -5,-16,-22,-18, -7, 2,-23, 4, 1,-15, 9, 7,-15,-20, -8,-13,-14,-10, -2,-17, 6, -9; /M: SY='R'; M=-13, 3,-28, 5, 4,-16,-19, 7,-19, 9,-14, -9, 2,-17, 2, 10, -9,-10,-18,-19, 3, 1; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 100 in 91 different sequences |
| Number of true positive hits | 100 in 91 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 3 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 97.09 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | K_Hofmann |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Feature key [info] | ZN_FING |
| Feature description [info] | ZZ-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
91 sequences
ADA2_CANAL (Q59WH0 ), ADA2_SCHPO (Q9P7J7 ), ADA2_YEAST (Q02336 ), BIG_ARATH (Q9SRU2 ), BIG_ORYSJ (B9G2A8 ), CBP1_CAEEL (P34545 ), CBP_HUMAN (Q92793 ), CBP_MOUSE (P45481 ), CBP_RAT (Q6JHU9 ), DMDA_DROME (Q9VDW6 ), DMDB_DROME (Q9VDW3 ), DMDD_DROME (Q0KI50 ), DMDE_DROME (Q7YU29 ), DMD_CAEEL (Q9TW65 ), DMD_CANLF (O97592 ), DMD_CHICK (P11533 ), DMD_HUMAN (P11532 ), DMD_MOUSE (P11531 ), DMD_PIG (Q5GN48 ), DMD_RAT (P11530 ), DRP2_HUMAN (Q13474 ), DRP2_MOUSE (Q05AA6 ), DRP2_RAT (Q9EPA0 ), DTN1_CAEEL (Q9Y048 ), DTNA_HUMAN (Q9Y4J8 ), DTNA_MOUSE (Q9D2N4 ), DTNB_HUMAN (O60941 ), DTNB_MOUSE (O70585 ), DTNB_RAT (P84060 ), DYTN_DANRE (A2CI97 ), DYTN_HUMAN (A2CJ06 ), DYTN_MOUSE (A2CI98 ), EP300_HUMAN (Q09472 ), EP300_MOUSE (B2RWS6 ), HAC12_ARATH (Q9FWQ5 ), HAC1_ARATH (Q9C5X9 ), HAC2_ARATH (Q9FYH1 ), HAC4_ARATH (Q9LG11 ), HAC5_ARATH (Q9LE42 ), HACL1_ORYSJ (Q6YXY2 ), HACL2_ORYSJ (Q5Z8V7 ), HACL3_ORYSJ (Q9XHY7 ), HERC2_HUMAN (O95714 ), HERC2_MOUSE (Q4U2R1 ), KCMF1_BOVIN (Q1LZE1 ), KCMF1_DANRE (Q7T321 ), KCMF1_DROME (Q95RX5 ), KCMF1_HUMAN (Q9P0J7 ), KCMF1_MOUSE (Q80UY2 ), KCMF1_XENLA (Q6GPB6 ), MIB1_DANRE (Q804S5 ), MIB1_HUMAN (Q86YT6 ), MIB1_MOUSE (Q80SY4 ), MIB1_XENLA (Q6GNY1 ), MIB2_CHICK (Q5ZIJ9 ), MIB2_HUMAN (Q96AX9 ), MIB2_MOUSE (Q8R516 ), MIB2_RAT (Q68LP1 ), MIB_DROME (Q9VUX2 ), NBR1_ARATH (Q9SB64 ), NBR1_HUMAN (Q14596 ), NBR1_MOUSE (P97432 ), NBR1_PONAB (Q5RC94 ), NBR1_RAT (Q501R9 ), PRT1_ARATH (Q8LBL5 ), REF2P_DROME (P14199 ), REF2P_DROSI (Q24629 ), SQSTM_HUMAN (Q13501 ), SQSTM_MOUSE (Q64337 ), SQSTM_PONAB (Q5RBA5 ), SQSTM_RAT (O08623 ), SWI3D_ARATH (Q8VY05 ), TAD2A_ARATH (Q9SFD5 ), TAD2B_ARATH (Q9ATB4 ), TAD2B_DANRE (Q503N9 ), TAD2B_DROME (Q8I8V0 ), TAD2B_HUMAN (Q86TJ2 ), TAD2B_PONAB (Q5RBN9 ), TAD2B_XENLA (Q6NRB5 ), TADA2_ORYSJ (Q75LL6 ), UTRO_HUMAN (P46939 ), VER2_CAEEL (O76695 ), Y3893_DICDI (Q54QG5 ), YN8B_SCHPO (Q9P792 ), YOY6_CAEEL (P34664 ), ZSWM2_HUMAN (Q8NEG5 ), ZSWM2_MOUSE (Q9D9X6 ), ZZEF1_HUMAN (O43149 ), ZZEF1_MOUSE (Q5SSH7 ), ZZZ3_HUMAN (Q8IYH5 ), ZZZ3_MOUSE (Q6KAQ7 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
3 sequences
RSC8_YEAST (P43609 ), SSR2_SCHPO (O14470 ), TAD2A_DROME (Q7KSD8 ) |
| PDB [Detailed view] |
23 PDB
1TOT; 2DIP; 2E5R; 2FC7; 2N1A; 4XI6; 4XI7; 4XIB; 5U7G; 5YP7; 5YP8; 5YPA; 5YPB; 5YPC; 5YPE; 5YPF; 5YPG; 5YPH; 6CW3; 6DS6; 6E83; 6E86; 6MJ7 » more |
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