PROSITE entry PS50847

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General information about the entry

Entry name [info]	GRAM_POS_ANCHORING
Accession [info]	PS50847
Entry type [info]	MATRIX
Date [info]	01-MAY-2002 CREATED; 26-FEB-2020 DATA UPDATE; 08-NOV-2023 INFO UPDATE.
PROSITE Doc. [info]	PDOC00373
Associated ProRule [info]	PRU00477

Name and characterization of the entry

Description [info]

Gram-positive cocci surface proteins LPxTG motif profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=39;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=36;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.9159126; R2=0.0060830; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3385.1904297; R2=0.9610918; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=918; H_SCORE=4267; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=590; H_SCORE=3952; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-49; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='L';  M= -97, -99,-115,-107, -70,-116, -98, -62,-108,  97, -58,-114,-114,-101,-105,-107, -93, -69,-101, -83;
/M: SY='P';  M=   5,-117, -97, -86,-115, -95, -99,-103, -93,-112, -99,-101, 127, -95,-104, -24, -87,-105,-109,-112;
/M: SY='D';  M= -12,-105,  48,  42,-104, -96,  -3,-101,  39, -31, -94,  25, -95,  41,  -7,   5,   3, -33,-110, -16;
/M: SY='T';  M= -21, -91, -88, -90, -98, -97, -98, -89, -87, -93, -90, -77, -89, -92, -96, -66, 120, -81,-118, -96;
/M: SY='G';  M= -27,-105, -93,-104,-112, 104, -99,-119, -98,-115,-104,  -9, -98, -96,-105, -32, -96,-112,-104,-107;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='E';  M=   2,-102,  60,  61,  -6, -93, -87,-101, -40, -75, -98,  36, -94, -79, -41,  32,  22, -28,-113, -96;
/M: SY='N';  M= -19,-101,   5,  42,-106,   3,  14, -32,  30,-103, -96,  53, -94, -38, -25,  33,  32, -52,-113, -97;
/M: SY='D';  M=   5,-103,  49,   4,-101,  14, -89,  11, -13, -46,  -5,  30, -30,  13, -19,  29,   4, -64,-110, -17;
/M: SY='N';  M= -29, -99, -17,   9, -61, -38, -20, -25, -19, -50,   8,  62,   7, -39, -90,  43,  51, -31,-108,  14;
/M: SY='N';  M=  -1,-102,   1, -19,  16, -78, -10,   0, -21,   7, -17,  54,  11,   5, -13,  21, -55,  11,  -8, -38;
/M: SY='F';  M=   3,-102, -27, -61,  34,  -1, -93,  13, -18,  28, -81,  26,   8,  -6, -19, -10,  -7, -25,  10,  15;
/M: SY='M';  M=  18,-100,-101, -98,  28,  16, -95,  -8, -43,  40,  53, -32,   8, -41, -99,   3,  20, -80,-100, -28;
/M: SY='T';  M=  35, -97, -96, -34,   2, -27,   9, -36, -39,  25,   2, -56,   6, -32, -96, -17,  64, -16,   9, -89;
/M: SY='L';  M=  33, -99,-107,-102, -16, -20,-102,  32,-101,  55, -24,-101,-105, -98,-103, -61,  19,  13,  38, -24;
/M: SY='G';  M=  37,-100,-104,-101,  29,  38,-101,   4,-101,  30,  -3, -97,  19, -98,-104, -27, -88,  24,-101, -88;
/I:         I=-20; MD=-50;
/M: SY='G';  M=  24,-105,-104,-105,  30,  68,-104, -48, -25,   9, -91, -93,-105,-101,-105, -36, -22, -21,  14, -93; D=-20;
/I:         I=-20; MD=-50;
/M: SY='L';  M=  38,-105, -73,-106, -94,  37,-104, -28,-106,  42,  -1,-101,-109,-101,-108,   2, -93,  -4,-109, -28; D=-20;
/I:         I=-20; MD=-50;
/M: SY='T';  M=  21,-118,-125,-122, -43, -34,-124,  -7,-120,  -1,  -6,-117,-123,-119,-124, -40,  22,  20,-130,-113; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='M';  M=  -9, -99,-109,-104,  31, -16, -98,  18,-103,  60,  63,-102,-107, -98,-103,  -3, -24,   9,-100, -81;
/M: SY='L';  M=  27, -98,-107,-102,  13, -16, -99,   6,-101,  57,  36,-100,-105, -97,-102,   7, -21,  23,-102, -85;
/M: SY='G';  M=  39,  10, -99, -99, -25,  44,-100,  -5, -97,  22, -12, -90,-100, -95,-102,  16,  31,   4,-106, -94;
/M: SY='L';  M=  36, -98,-107,-102, -33,  -9,-102,  39,-102,  54,   5,-100,-105, -97,-103,   0, -46,  19,-104, -89;
/M: SY='G';  M=  26,-100,-100,-100,  -7,  59,-100, -13, -43,  19,   4, -90,-101, -95,-101,  22, -17,  12,-105, -94;
/M: SY='G';  M=  12,  12, -95, -49, -30,  78, -98, -29, -97,  -7, -94, -85, -99, -94,-103,  31,   5, -95,-104, -24;
/M: SY='L';  M=  42, -98,-104, -99, -83, -63,   9,  12,-100,  59, -17, -98,-104, -95,-101,   7,  12,   0,-106, -44;
/M: SY='F';  M=   9, -17,-108,-104,  48,   7, -98,  -1, -44,  34,  22,-101,-108,-100, -39, -47, -48,  40, -95,  23;
/M: SY='L';  M=  11,-102,-109,-105,  14,  -1,-100,  36,-101,  61, -71,-104,-109, -52, -15, -47, -58, -15, -98,   8;
/M: SY='Y';  M=  -3,-104,-108,-102,  35, -30, -95,  21, -15,  41, -12,-102, -37, -97,   4, -48, -56,  10,  -6,  55;
/M: SY='K';  M=   7,-104, -97, -90,  -4,  15,  11, -39,  48, -20,  -5, -89,-102, -85,  43, -22,  -4,  18,-102,  15;
/M: SY='R';  M= -24,-108, -91, -49, -15, -60, -88,-105,  68, -49, -94, -28,-101, -15,  84, -11, -29, -55,-105, -93;
/M: SY='K';  M= -39,-109, -33, -80, -29, -37, -86,-109,  76,-107, -97,  30,  -3, -75,  75, -33, -90,-105,-105, -36;
/M: SY='R';  M= -55,-110, -87,   6,-108,-103,  -3,-111,  70,-106, -96, -27, -99,   7,  87, -88,  -8,-105,-107, -95;
/M: SY='K';  M= -14,-112,  -5,  32, -40,-104, -92, -47,  79,-109,-100, -25, -24, -77,  46, -91, -43,-105,-110,-100;
/M: SY='N';  M= -56,-112, -12,  29,-115,  -7,  -4, -44,  -7, -60,-103,  67,-106,  34,   9,  17, -92, -63,-121,-105;
/M: SY='N';  M= -24,-118,  29, -24,-121, -16,  14,-116,  15, -73,-112,  31,-113, -11, -58,  25, -25, -24,-130,-112;
/M: SY='K';  M=-120,-137,   5, -21,-139, -26, -16,-135,  38,-137,-129,   0,-128,-108, -17,  -7,-116, -38,-143,-128;
/M: SY='K';  M=  -6,-144, -11,-123,-146,-135,-131, -32,  19,-140,-134,  15,-141,-122, -13,-125,-127, -52,-153,-139;
/M: SY='K';  M=-147,-160, -46,   8, -18,-155,-140,-158,   9,-155,-150, -30,-149,-129, -24,-140, -39,-155,-157,-143;
/M: SY='H';  M=-162,-174, -60, -70,-164,-170,   4,-160, -27, -30,-149, -64,-168,  -1,-147,-155, -56,-162,-178,-156;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_05 which contains 570'420 sequence entries.

Total number of hits	204 in 204 different sequences
Number of true positive hits	204 in 204 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	2

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Taxonomic range [info]	Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Feature key [info]	MOTIF
Feature description [info]	LPXTG sorting signal
Version [info]	8

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

204 sequences

ARP4_STRPY  (P13050), ASA1_ENTFA  (P17953), BAG_STRAG   (P27951),

BBP_STAAR   (Q6GJA6), BBP_STAAU   (Q14U76), BCA_STRA1   (Q02192), 
C5AP_STRP1  (P58099), C5AP_STRP3  (P0DD34), C5AP_STRP6  (Q5X9R0), 
C5AP_STRP8  (Q8NZ80), C5AP_STRPQ  (P0DD35), C5AP_STRPY  (P15926), 
CHPA_STRCO  (Q8CJY7), CHPB_STRCO  (Q9X7U2), CHPC_STRCO  (Q9AD93), 
CLFA_STAA8  (Q2G015), CLFA_STAAC  (Q5HHM8), CLFA_STAAE  (Q53653), 
CLFA_STAAM  (Q932C5), CLFA_STAAN  (Q99VJ4), CLFA_STAAR  (Q6GIK4), 
CLFA_STAAS  (Q6GB45), CLFA_STAAW  (Q8NXJ1), CLFB_STAA8  (Q2FUY2), 
CLFB_STAAC  (Q5HCR7), CLFB_STAAE  (O86476), CLFB_STAAM  (Q99R07), 
CLFB_STAAN  (Q7A382), CLFB_STAAR  (Q6GDH2), CLFB_STAAS  (Q6G644), 
CLFB_STAAW  (Q8NUL0), CNA_STAAU   (Q53654), DEXT_STRDO  (P39653), 
DEXT_STRMU  (Q54443), FAP1_STRPA  (A1C3L3), FBE_STAEP   (O70022), 
FM1_ACTVI   (P18477), FM2_ACTNA   (P12616), FNBA_STAA1  (A7X6I5), 
FNBA_STAA3  (Q2FE03), FNBA_STAA8  (P14738), FNBA_STAAB  (Q2YW62), 
FNBA_STAAC  (Q5HD51), FNBA_STAAM  (Q99RD2), FNBA_STAAN  (Q7A3J7), 
FNBA_STAAR  (Q6GDU5), FNBA_STAAS  (Q6G6H3), FNBA_STAAW  (Q8NUU7), 
FNBB_STAA3  (A0A0H2XKG3), FRUA_STRMU  (Q03174), GH101_RENSM (A9WNA0), 
GH101_STRPN (Q2MGH6), GH101_STRR6 (Q8DR60), GSPB_STRGN  (Q939N5), 
HSA_STRGC   (A8AWU7), HYSA_STRPN  (Q54873), IGA1A_STRPN (Q97QP7), 
IGA1B_STREE (Q54875), IGA1_STRR6  (Q59947), IGA1_STRSA  (Q59986), 
INLA_LISM4  (G2K3G6), INLA_LISMF  (Q723K6), INLA_LISMO  (P0DJM0), 
INLI_LISMF  (Q723X5), INLI_LISMO  (Q8YA32), INLJ_LISMF  (Q71VU0), 
INLJ_LISMO  (Q8Y3L4), INUS_LACJO  (Q74K42), ISDA_STAA1  (A7X148), 
ISDA_STAA2  (A6U0U7), ISDA_STAA3  (Q2FHV1), ISDA_STAA8  (Q2FZE9), 
ISDA_STAA9  (A5IS16), ISDA_STAAB  (Q2YX95), ISDA_STAAC  (Q5HGV4), 
ISDA_STAAE  (A6QG31), ISDA_STAAM  (Q99UX4), ISDA_STAAN  (Q7A655), 
ISDA_STAAR  (Q6GHV6), ISDA_STAAS  (Q6GA85), ISDA_STAAT  (A8Z1R0), 
ISDA_STAAU  (P0C1S5), ISDA_STAAW  (Q7A152), ISDB_STAA1  (A7X146), 
ISDB_STAA2  (A6U0U6), ISDB_STAA3  (Q2FHV2), ISDB_STAA8  (Q2FZF0), 
ISDB_STAA9  (A5IS15), ISDB_STAAB  (Q2YX96), ISDB_STAAC  (Q5HGV5), 
ISDB_STAAE  (A6QG30), ISDB_STAAM  (Q99UX5), ISDB_STAAN  (Q7A656), 
ISDB_STAAR  (Q6GHV7), ISDB_STAAS  (Q6GA86), ISDB_STAAT  (P0C7J5), 
ISDB_STAAW  (Q8NX66), ISDH_STAA3  (Q2FG07), ISDH_STAA8  (Q2FXJ2), 
ISDH_STAAB  (Q2YTF7), ISDH_STAAC  (Q5HF43), ISDH_STAAM  (Q931P4), 
ISDH_STAAN  (Q99TD3), ISDH_STAAS  (Q6G8J7), ISDH_STAAW  (Q8NW39), 
LEVS_FRUSA  (Q70XJ9), LEVS_LACGS  (D3WYW0), M12_STRPY   (P19401), 
M21_STRPY   (P50468), M22_STRPY   (P50469), M24_STRPY   (P12379), 
M49_STRP9   (P16947), M5_STRP5(P02977), M6A_STRP6   (Q5X9Q9), 
M6B_STRPY   (P08089), MANA_BIFAA  (A1A278), MRP4_STRPY  (P30141), 
MRP_STRSU   (P32653), MX_STRP9(P16946), NANA_STREE  (P62575), 
NANA_STRR6  (P62576), NISP_LACLL  (Q07596), NTPES_BACSU (O34313), 
P1P_LACLC   (P16271), P2P_LACLC   (P15293), P2P_LACPA   (Q02470), 
P3P_LACLS   (P15292), PAA_STRCG   (Q9LBG3), PAB_FINMA   (Q51911), 
PAC_STRMG   (P11657), PADA_STRGC  (A8AZP4), PAS_STRIT   (Q9KW51), 
PFBA_STRR6  (Q8CYC9), PLS_STAAC   (Q5HJU7), PLS_STAAM   (Q931E9), 
PLS_STAAN   (P61598), PLS_STAAU   (P80544), PLS_STAAW   (Q8NUV0), 
PLS_STAES   (Q8CQD9), PSRP_STRPN  (A0A0H2URK1), PULA_STREE  (Q9F930), 
PULA_STRP2  (A0A0H2ZL64), PULA_STRPN  (A0A0H2UNG0), SASG_STAA8  (Q2G2B2), 
SDRC_STAA3  (Q2FJ79), SDRC_STAA8  (Q2G0L5), SDRC_STAAC  (Q5HIB4), 
SDRC_STAAE  (O86487), SDRC_STAAM  (Q99W48), SDRC_STAAN  (Q7A781), 
SDRC_STAAR  (Q6GJA7), SDRC_STAAS  (Q6GBS6), SDRC_STAAW  (Q8NXX7), 
SDRD_STAA3  (Q2FJ78), SDRD_STAA8  (Q2G0L4), SDRD_STAAC  (Q5HIB3), 
SDRD_STAAE  (O86488), SDRD_STAAM  (Q99W47), SDRD_STAAN  (Q7A780), 
SDRD_STAAS  (Q6GBS5), SDRD_STAAW  (Q8NXX6), SDRE_STAA3  (Q2FJ77), 
SDRE_STAAC  (Q5HIB2), SDRE_STAAE  (O86489), SDRE_STAAM  (Q932F7), 
SDRE_STAAN  (Q99W46), SDRE_STAAS  (Q6GBS4), SDRE_STAAW  (Q8NXX5), 
SDRF_STAEP  (Q9KI14), SDRF_STAES  (Q8CMP4), SDRG_STAEP  (Q9KI13), 
SDRI_STASA  (Q8KWM1), SPAA_STRDO  (P21979), SPAP_STRMU  (P23504), 
SPA_STAA8   (P02976), SPA_STAAE   (A0A0H3K686), SPA_STAAM   (P0A015), 
SPA_STAAN   (P99134), SPA_STAAU   (P38507), SPG1_STRSG  (P06654), 
SPG2_STRSG  (P19909), SPH_STRP1   (P50470), SRAP_STAA3  (Q2FDK5), 
SRAP_STAA8  (Q2FUW1), SRAP_STAAC  (Q5HCP3), SRAP_STAAM  (Q99QY4), 
SRAP_STAAN  (Q7A362), SRAP_STAAR  (Q6GDE9), SRAP_STAAS  (Q6G620), 
SRAP_STAAU  (Q8VQ99), SRAP_STAAW  (Q8NUJ3), SRAP_STAHJ  (Q4L9P0), 
SSPA_STRGC  (A8AUS0), SSPB_STRGC  (A8AUS1), SSPB_STRGN  (P16952), 
STRH_STRPN  (P49610), TEE6_STRP6  (P18481), UAFA_STAS1  (Q4A0V8), 
WAPA_STRMU  (P11000), Y2714_LISMO (Q8Y3W5), YHCR_BACSU  (P54602), 
ZMPB_STRPN  (Q9L7Q2), ZMPB_STRR6  (Q8DQN5), ZMPC_STRPN  (Q97T80)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
'Partial' sequences

2 sequences

M32_STRTR   (P83330), PAM_STRPY   (P49054)