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| Entry: PS51140 |
General information about the entry
| Entry name [info] | CUE |
| Accession [info] | PS51140 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2005 CREATED;
01-OCT-2013 DATA UPDATE; 05-JUN-2019 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51140 |
| Associated ProRule [info] | PRU00468 |
Name and characterization of the entry
| Description [info] | CUE domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=44; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=44; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0788274; R2=0.0083074; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=966; N_SCORE=10.1; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=846; N_SCORE=9.1; MODE=1; TEXT='R?'; /DEFAULT: M0=-31; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-105; BD=-105; /M: SY='E'; M= -23, -13, 24, 45, -87, -86, -13, 16, -18, -48, 28, -29, -84, 43, 1, 31, -30, 20, -99, -81; /M: SY='H'; M= -49, -90, -6, -17, -3, -87, 41, -5, -20, 9, 29, 39, 11, -1, 22, -6, 39, -18, -97, -75; /M: SY='D'; M= -19, -92, 47, 41, -30, -82, -8, -87, 9, -13, 16, 42, 9, 28, -30, 15, -2, -85, -99, -82; /M: SY='N'; M= 18, -19, 6, 36, -93, -23, -2, -86, -17, -54, 15, 40, 24, 30, -17, 26, -2, -28, -99, -85; /M: SY='M'; M= 14, -7, 6, 27, -82, -45, 29, -6, 34, 11, 58, -24, -86, 1, -73, -75, -10, 9, -97, -78; /M: SY='V'; M= 3, -86, -98, -92, -1, -97, -90, 37, -90, 45, 22, -93, -95, -88, -44, -83, -10, 57, -90, 2; /M: SY='H'; M= -27, -7, 16, 49, -90, -85, 61, -41, 16, -21, 17, -26, -82, 39, -7, 23, 18, -84,-100, -79; /M: SY='Q'; M= -13, -3, 10, 19, -33, -84, -9, -19, -3, -51, -10, -25, -84, 57, -15, 24, 50, -24, -92, 21; /M: SY='L'; M= -80, -87,-102, -96, 0,-103, -91, 44, -94, 67, 23, -98, -98, -91, -94, -91, -77, 48, -91, -71; /M: SY='Q'; M= -25, -93, -80, -68, -83, -88, 16, -2, 58, 1, 53, -73, -86, 73, 3, -19, -11, -23, -91, -18; /M: SY='E'; M= -23, -93, 47, 71, -97, -46, -72, -52, 4, -55, -86, 16, -80, 42, -70, 28, -1, -88,-100, -86; /M: SY='M'; M= 0, -87, -92, 1, -69, -93, -82, 16, -37, 46, 102, -89, -91, -79, -85, -16, -75, 14, -93, -74; /M: SY='F'; M= -21, -88,-104, -99, 120, -98, -86, -38, -95, -1, -66, -94,-102,-103, -93, -90, -84, -69, -61, -40; /M: SY='P'; M= -84,-109, -84, -73,-104, -86, -87, -91, -80,-102, -88, -91, 131, -84, -93, -81, -76, -97, -97,-101; /M: SY='D'; M= -28, -92, 63, 8, -32, -23, 40, -40, -32, -90, -19, 47, -84, 57, -74, 22, 15, -88,-103, -80; /M: SY='V'; M= -24, -7, -98, -92, 10, -98, -8, 31, -88, 46, 46, -92, -95, -87, -15, -85, -12, 47, 40, -23; /M: SY='D'; M= -40, -94, 72, 25, -98, 12, 24, -97, -73, -97, -90, -19, 50, -70, -31, 38, 12, -92,-105, -87; /M: SY='P'; M= -14, -7, 22, 30, -87, -86, -78, -36, 17, -21, -77, 10, 49, 16, -1, 5, -31, 21, -96, -6; /M: SY='E'; M= -24, -92, 42, 53, -31, 12, -13, -89, -16, -57, -85, -2, -28, 2, -32, 37, 3, -22, 8, -20; /M: SY='Q'; M= -2, -90, -12, -1, 36, -92, 14, 33, -17, 14, -65, -29, -90, 47, -80, -77, 4, 29, -88, -24; /M: SY='I'; M= -10, -90,-101, -96, -67,-102, -97, 84, -94, 38, -54, -95, -24, -91, -96, -88, -75, 37, -93, -75; /M: SY='R'; M= 5, -92, -31, 28, -87, -88, -13, -40, 30, -2, -15, -74, -86, 36, 58, -2, 3, 1, -95, -81; /M: SY='D'; M= 23, 30, 44, 19, -83, -24, -7, -89, -1, -52, -81, -71, -86, 38, 27, -1, -12, -44, 15, 40; /M: SY='C'; M= -12, 70, 48, -32, -79, -92, 32, 20, -85, 12, -68, -78, -92, -22, -88, -22, -31, 52,-104, -80; /M: SY='L'; M= -45, -11,-101, -94, -21,-102, -87, 0, -94, 85, 0, -99,-100, -89, -92, -92, -79, 7, -88, -14; /M: SY='R'; M= 3, -93, -30, 42, -5, -88, -77, 25, 9, -2, -72, -21, -86, 37, 42, 8, -75, -21, -91, -24; /M: SY='E'; M= 43, -89, -5, 43, -91, -80, -16, -19, 22, -55, -80, 19, -82, 34, 3, 14, 2, -80, -95, -26; /I: I=-13; MD=-27; /M: SY='Y'; M= -4, 21, -82, -85, -82, -88, 51, -98, -21, -96, -88, 53, -99, 2, -8, 32, -80, -96, -92, 65; D=-13; /I: I=-13; MI=-27; MD=-27; IM=-27; DM=-27; /M: SY='N'; M= -78, -2, 48, 10, -91, -2, 33, -92, -13, -38, -84, 54, -86, -6, 22, -20, 48, -88,-103, -16; D=-13; /I: I=-13; DM=-27; /M: SY='G'; M= -77, -95, -6, -40, -12, 66, -3, -96, -16, -95, -88, 55, -91, -4, 1, -18, -80, -45, 12, 27; D=-13; /I: I=-13; DM=-27; /M: SY='N'; M= -19, 6, 71, -65, -30, -76, -71, -90, -15, -93, -14, 76, -87, -14, -14, 40, -30, -32,-106, -84; /M: SY='V'; M= -27, -88, -94, -87, -3, -96, -89, 37, -19, 34, -8, -88, -35, -1, -10, -8, -35, 60, -92, -21; /M: SY='E'; M= -11, -10, 70, 80,-101, -27, -72, -99, -66, -95, -90, 1, -79, 29, -74, -20, -12, -92,-103, -89; /M: SY='Q'; M= 31, -89, -9, 5, -85, -45, -10, -5, -74, 22, -71, 2, 24, 51, -32, 8, 20, -39, -96, -82; /M: SY='T'; M= 58, 59, -85, -82, -85, -81, -90, -14, -35, -76, -74, -76, -85, -82, -86, -27, 71, 31,-101, -85; /M: SY='I'; M= -42, 49, -97, -94, 12, -98, -6, 76, -91, -37, 29, -88, -93, -89, -93, -4, -12, 41, -90, 7; /M: SY='N'; M= 20, -89, 53, 44, -95, -42, -72, -89, -33, -51, -85, 66, -83, 30, -75, 11, -20, -23,-103, -87; /M: SY='M'; M= 33, -87, -29, -2, -83, -80, -12, -73, 1, -17, 59, 44, -25, -2, 16, 21, -70, 13, -96, -18; /M: SY='L'; M= -14, 17,-101, -95, -28,-101, -89, 53, -94, 74, -51, -97, -98, -89, -94, -90, -78, -11, -88, -7; /M: SY='L'; M= -48, -12, -95, -89, 19, -98, -12, 5, -3, 72, -10, -31, -96, -84, -30, -38, -12, 6, -89, -70; /I: I=-15; MD=-32; /M: SY='E'; M= 4, -8, 23, 60, -40, -50, -73, -90, 13, -54, -9, 30, -83, 35, 1, 6, -30, -46, -95, -4; D=-15; /I: I=-15; MI=-32; IM=-32; DM=-32; /M: SY='M'; M= -23, -92, 28, 12, -31, 39, -78, 0, -78, 31, 44, -3, -89, 4, -2, -35, -78, -39, -91, 0; /M: SY='S'; M= -3, -90, -13, 18, -34, 6, -77, -39, 10, -48, -81, 20, -26, 18, 28, 41, 20, -22, 13, -82; /M: SY='H'; M= -10, -91, 39, 29, -29, -28, 46, 8, -13, 10, 15, -21, -30, -22, -79, 1, 14, -11, -96, -18; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 87 in 82 different sequences |
| Number of true positive hits | 87 in 82 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 6 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 93.55 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | PS_Langendijk_Genevaux |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Feature key [info] | DOMAIN |
| Feature description [info] | CUE |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
82 sequences
AMFR_HUMAN (Q9UKV5 ), AMFR_MOUSE (Q9R049 ), ASCC2_DICDI (Q54VC4 ), ASCC2_HUMAN (Q9H1I8 ), ASCC2_MOUSE (Q91WR3 ), AUP1_CAEEL (P34426 ), AUP1_DANRE (Q6PBN5 ), AUP1_HUMAN (Q9Y679 ), AUP1_MOUSE (P70295 ), AUP1_RAT (A1L134 ), AUP1_XENLA (B1H1N7 ), AUP1_XENTR (A9ULG4 ), CID5_ARATH (Q9LYE5 ), CID6_ARATH (Q6NQH9 ), CUE1_ASHGO (Q756I2 ), CUE1_CANAL (Q59NY7 ), CUE1_CANGA (Q6FS98 ), CUE1_DEBHA (Q6BKU8 ), CUE1_KLULA (Q6CNN5 ), CUE1_YEAST (P38428 ), CUE2_YEAST (P36075 ), CUE3_SCHPO (O74485 ), CUE3_YEAST (P53137 ), CUE4_SCHPO (P87238 ), CUE4_YEAST (Q04201 ), CUE5_SCHPO (O14319 ), CUE5_YEAST (Q08412 ), CUED1_HUMAN (Q9NWM3 ), CUED1_MOUSE (Q8R3V6 ), CUED2_BOVIN (Q3ZBN4 ), CUED2_HUMAN (Q9H467 ), CUED2_MOUSE (Q9CXX9 ), CUED2_RAT (A1L131 ), DEF1_CANAL (Q5AMM4 ), DEF1_CANAW (C4YHS3 ), DEF1_CANTT (C5M2B8 ), DEF1_CLAL4 (C4Y1P0 ), DEF1_DEBHA (Q6BRB3 ), DEF1_KLULA (Q6CTH5 ), DEF1_LACTC (C5DGU9 ), DEF1_LODEL (A5E406 ), DEF1_YEAS2 (C7GP20 ), DEF1_YEAS7 (A6ZZR2 ), DEF1_YEAST (P35732 ), DEF1_ZYGRC (C5E4K0 ), DON1_YEAST (Q05610 ), HRDL1_CAEBR (A8WWR3 ), HRDL1_CAEEL (P90859 ), N4BP2_HUMAN (Q86UW6 ), RIN2_ARATH (Q8VYC8 ), RIN3_ARATH (Q8W4Q5 ), SMRCD_BOVIN (E1B7X9 ), SMRCD_HUMAN (Q9H4L7 ), SMRCD_MOUSE (Q04692 ), SMRCD_RAT (D3Z9Z9 ), SMRCD_XENTR (Q5FWR0 ), SMRDA_DANRE (B0R061 ), SMRDB_DANRE (E7F1C4 ), TAB2_DANRE (Q5RFW2 ), TAB2_HUMAN (Q9NYJ8 ), TAB2_MOUSE (Q99K90 ), TAB2_RAT (Q5U303 ), TAB3_HUMAN (Q8N5C8 ), TAB3_MOUSE (Q571K4 ), TAB3_XENLA (Q7ZXH3 ), TOIPA_ONCMY (Q4LBC8 ), TOIPA_XENLA (Q3B8H2 ), TOIPB_ONCMY (Q4LBC7 ), TOIPB_XENLA (Q6INE3 ), TOLIP_BOVIN (Q2LGB5 ), TOLIP_CHICK (Q5ZK05 ), TOLIP_DANRE (Q7ZV43 ), TOLIP_ESOLU (C1BZR1 ), TOLIP_HUMAN (Q9H0E2 ), TOLIP_MOUSE (Q9QZ06 ), TOLIP_RAT (A2RUW1 ), TOLIP_SALSA (B5X370 ), TOLIP_XENTR (Q6DFR0 ), VPS91_SCHPO (O74396 ), VPS9_YEAST (P54787 ), YGVA_SCHPO (O43024 ), YR75_CAEEL (Q09394 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
6 sequences
CID7_ARATH (O64843 ), CUE2A_XENLA (Q6NU18 ), CUE2B_XENLA (Q68F60 ), CUED2_DANRE (Q6TLH3 ), DEF1_ASHGO (Q75DE9 ), DEF1_CANGA (Q6FIN4 )» more |
| PDB [Detailed view] |
15 PDB
1MN3; 1OTR; 1P3Q; 1WGL; 2DAE; 2DHY; 2DI0; 2EJS; 2EKF; 2LVN; 2LVO; 2LVP; 2LVQ; 2MYX; 4G3O » more |
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