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PROSITE entry PS51507


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PURL: https://purl.expasy.org/prosite/signature/PS51507

Direct ScanProsite submission
General information about the entry

Entry name [info] IRF_2
Accession [info] PS51507
Entry type [info] MATRIX
Date [info] 01-AUG-2010 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00522
Associated ProRule [info] PRU00840

Name and characterization of the entry

Description [info] IRF tryptophan pentad repeat DNA-binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=107;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=102;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8007126; R2=0.0069866; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=18028.2734375; R2=1.6174334; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=816; H_SCORE=19348; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=530; H_SCORE=18886; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-49; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 34 in 34 different sequences
Number of true positive hits 34 in 34 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DNA_BIND
Feature description [info] IRF tryptophan pentad repeat
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
34 sequences

IRF1_BOVIN  (Q3SZP0), IRF1_CHICK  (Q90876), IRF1_HUMAN  (P10914), 
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PDB
[Detailed view]
19 PDB

pdb_00001if1; pdb_00001irf; pdb_00001irg; pdb_00001t2k; pdb_00002dll; pdb_00002irf; pdb_00002o61; pdb_00002o6g; pdb_00002pi0; pdb_00003qu3; pdb_00003qu6; pdb_00004hly;
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