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Entry: PS51674

General information about the entry

Entry name [info] 4FE4S_WBL
Accession [info] PS51674
Entry type [info] MATRIX
Date [info] 01-MAY-2013 CREATED;
10-MAY-2017 DATA UPDATE;
12-AUG-2020 INFO UPDATE.
PROSITE Doc. [info] PDOC51674
Associated ProRule [info] PRU01010

Name and characterization of the entry

Description [info] 4Fe-4S WhiB-like (Wbl)-type iron-sulfur binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=62;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=57;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3765483; R2=0.0082260; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8140.4462891; R2=2.2116711; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1049; H_SCORE=10460; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=502; H_SCORE=9251; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='A';  M=  61, -77, -75, -43, -76, -26, -21, -41, -30,   8, -64, -37,  43, -55,  24,  -5, -12,   1, -85, -75;
/M: SY='C';  M= -56, 155, -89, -89, -79, -84, -89, -86, -85, -77, -77, -75,-100, -92, -91, -72, -69, -74,-109, -90;
/M: SY='R';  M=  42, -17, -48, -54, -58, -23,  16, -15, -25, -27, -36, -49, -33,  -4,  67,  -7,  -2,   4, -84, -17;
/I:         I=-23; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='G';  M= -23, -95,  23,   2, -37,  33,  -5, -67, -39, -54, -85, -42, -29,  28, -52,   8,  -7, -48, -96, -18; D=-23;
/I:         I=-23; DM=-58;
/M: SY='G';  M=  24, -80,  16,   5, -39,  30, -18, -36, -54, -32,  25, -42, -30,   2,   4, -19,  25,  10,  26, -10;
/M: SY='D';  M= -25, -85,  92,  -1, -38, -29, -14, -52, -30, -47, -79,  30, -10,  -4,  -5, -15,  -2, -81, -96, -38;
/M: SY='P';  M=  -1, -89,  -6, -22, -39, -28,   8, -77, -59, -73, -40, -71, 103, -27, -31,  -4,  12, -29,  17, -54;
/M: SY='D';  M= -10, -86,  77,  69, -63, -22, -43, -75, -28, -43, -79, -20, -12, -13, -33, -22, -30, -70, -92, -31;
/M: SY='L';  M=  11, -37, -35, -35, -22, -71, -37,  15, -42,  60,  29, -79,  -1, -24, -13, -52, -13, -11,  20, -48;
/M: SY='W';  M= -52, -87, -52, -51,  99, -86, -81, -55, -82, -44, -21, -88, -62, -86, -82, -82, -54, -62, 131,  19;
/M: SY='F';  M= -28, -48,  38, -55,  94, -48,  10, -48, -76, -20, -32, -70, -66, -32, -62, -50,   7, -49,  26,  35;
/I:         I=-16; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='P';  M= -29, -62,  -5,  -5, -66,   7, -40, -84, -68, -81, -39, -29,  27, -90, -20, -33, -22, -26, -28, -30; D=-16;
/I:         I=-16; DM=-41;
/M: SY='E';  M= -45,-109,  20,  51, -65, -30, -26,-104, -33, -39, -26, -84, -15, -23, -24, -43, -44,-101, -24, -97; D=-16;
/I:         I=-16; DM=-41;
/M: SY='P';  M= -24,-100,  20, -19,-102, -10, -29, -74, -39, -70, -92, -16,  31, -32,  18,  -5,  17, -58,-108, -94; D=-16;
/I:         I=-16; DM=-41;
/M: SY='R';  M=   6, -48, -14,   5, -46,  17,   1, -63, -28, -56, -86, -23,  16, -31,  19, -23, -17, -36, -27, -88; D=-16;
/I:         I=-16; DM=-41;
/M: SY='P';  M=  10, -88,  11,  11, -72,   5, -25, -71, -36, -80, -34,  -8,  53,  -7,  23,  15,  -6, -45, -91, -26; D=-16;
/I:         I=-16; DM=-41;
/M: SY='E';  M=  17, -86,  22,  29, -49,  -6, -20, -38, -40, -21, -73, -30,  23,  18,   8,   3,  -8, -15,   2, -35; D=-16;
/I:         I=-16; DM=-41;
/M: SY='R';  M=   7, -84,  29,   1, -79,  -5,  -4, -39, -10, -52, -52,   1,  14,  -2,  57,   3,  -3, -32,  19,  -4; D=-16;
/I:         I=-16; DM=-41;
/M: SY='R';  M=  10, -82,  -3,  -5, -47,   4,  17, -32,  -5, -24, -31, -55,  20,   3,  49,  29,   8, -31, -85, -30;
/M: SY='R';  M=  23, -81,   7,  22, -60, -18,   2, -28,   7, -26, -50, -16, -62,  17,  40,   2,   7,  -8,  14,  -6;
/M: SY='R';  M=  -2, -51,  14,   9, -40, -43,  -3, -39,  -5, -11, -22, -51, -10,  34,  69,   6, -12, -35, -85, -51;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='E';  M=  17, -41, -12,  38, -35, -51,  25,  12, -34, -10, -63,  -6, -20,  14,  28, -36,  11,   4, -23, -10;
/M: SY='R';  M=  38, -81,  28,  35, -83, -36,  -6, -37,  -1, -44, -71, -51, -19,   7,  49,  -9,   7, -43, -87, -47;
/M: SY='R';  M=  33, -81, -38,  37, -48, -75,  20, -57,  14, -15, -34, -41, -19,  32,  40, -43,  21, -21, -22, -34;
/M: SY='A';  M=  95,  -8, -77, -69, -81, -37, -77, -40, -71, -40, -10, -71, -49, -58, -64, -51, -61, -34, -84, -78;
/M: SY='K';  M=  15, -38, -71, -43, -78, -79, -68, -11,  67, -16,   7, -64, -77,  13,  64, -65, -25, -10, -83, -71;
/M: SY='R';  M=  49, -80,   7,  16, -83, -50, -17, -33,  14, -39, -36, -38, -75,  29,  52,  -4,   2, -63, -86, -74;
/M: SY='I';  M= -10, -78, -87, -64,  -9, -61, -46,  57, -55,  36,   1, -81, -84, -35, -46, -46, -11,  51, -14, -30;
/M: SY='C';  M= -69, 155, -89, -89, -79, -85, -89, -86, -85, -77, -77, -75,-100, -93, -91, -72, -69, -74,-109, -90;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='A';  M=  45, -80,  11,  -8, -64,   6,  29, -60, -47, -14,   7, -15, -77,  22,  38,   3, -11, -45,  11, -39;
/M: SY='R';  M=  14, -81,  10, -12, -83,  33,   3, -67, -25, -44,  -7, -12, -49,  22,  47,  20,  22, -42, -44, -74;
/M: SY='C';  M= -69, 155, -89, -89, -79, -85, -89, -86, -85, -77, -77, -75,-100, -93, -91, -72, -69, -74,-109, -90;
/M: SY='P';  M= -32, -95, -51, -23, -60, -61, -35, -81, -69, -89, -60, -43, 122, -48, -55, -25, -39, -63, -87, -87;
/M: SY='V';  M= -16, -75, -89, -83, -15, -75, -30,  11, -79,   6, -19, -84, -86, -81, -23, -64, -47,  90, -90, -55;
/M: SY='R';  M= -11, -84, -77, -66, -35, -84, -68,  13,   5,  20,   6, -70, -82,  18,  83, -41, -40,  -8,   7, -66;
/M: SY='R';  M=  36, -49,  31,  23, -51, -12, -23, -53, -22, -13, -14, -64, -38,  21,  39, -37,   8,  -6, -20, -37;
/M: SY='Q';  M=  30, -84,  26,  60, -85, -52, -30, -66, -19, -23, -34, -63,  12,  60,  -1, -29, -26, -57,  -6, -75;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='C';  M= -69, 155, -89, -89, -79, -85, -89, -86, -85, -77, -77, -75,-100, -93, -91, -72, -69, -74,-109, -90;
/M: SY='L';  M=  37, -79, -48, -13, -54, -32, -29, -29, -42,  56, -53, -35, -82, -14,  50, -55, -36, -59, -82, -68;
/M: SY='Q';  M=  37, -80,  28,  41, -45, -38, -46, -59, -16, -63, -72, -16, -73,  43,  25,  -3,  26, -39, -86, -27;
/M: SY='W';  M=  -6, -86,  29,  -1,  23, -41,  54, -71, -51,  -9, -65, -16, -81,  -7,  -6, -20, -39, -33,  92,  64;
/M: SY='A';  M=  89, -72, -48, -38, -41,   5, -77, -56, -70, -51, -68, -69, -75, -28, -44, -22, -35, -19, -83, -77;
/M: SY='L';  M=   0, -20,  -5, -12, -42, -30, -75,  14, -50,  58,  26, -45, -83, -20, -15, -28, -48,  22, -84, -66;
/M: SY='E';  M=  20, -81,  35,  41, -64, -34, -16, -40,  -8, -30, -42, -14, -27,   4,  29,  -9,  21,   4, -39, -57;
/M: SY='N';  M= -20, -37,  -3,  15, -14, -41,  35, -51, -41,  -1,   9,  46, -56,   7,  20,   0,  30,  -7,  32, -27;
/M: SY='R';  M=   1, -34,  24,  31, -64,  28,  29, -85, -27, -55, -75,  25,  38,  -3,  42, -41, -35, -72, -87, -29;
/M: SY='E';  M=  -3, -84,  42,  70, -48, -27,   9, -53, -49, -23, -25, -21, -15,   7,  10, -13, -34, -14,  -1, -55;
/I:         I=-24; MD=-60;
/M: SY='P';  M=  -6, -20, -10,  23, -79, -19,  18, -34, -21, -27, -24, -19,  54,  20,  28,  -3,  13, -17,  26, -34; D=-24;
/I:         I=-24; MD=-60;
/M: SY='H';  M=  -6, -20,  -7, -19,  25,   2,  75, -57, -58, -32, -70, -24, -34, -40, -41, -14,   0, -23,  39,  45; D=-24;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='G';  M= -24, -45, -73, -83, -62, 100, -35, -92, -77, -78,  -9, -46, -76, -74, -84, -42, -53, -62, -82, -83;
/M: SY='V';  M= -65, -78, -90, -85, -10, -92, -88,  57, -81, -28,  30, -83, -84, -82, -54, -75,  -8,  81, -10, -22;
/M: SY='W';  M= -40, -97, -98, -83,   1, -63, -91, -31, -73, -43, -72, -92, -86, -76,  15, -82, -43,   1, 162,  25;
/M: SY='G';  M=  57, -78, -73, -77, -88,  85, -78, -87, -74, -86, -77, -62, -75, -71, -56, -21, -69, -60, -83, -83;
/M: SY='G';  M=   2, -83, -72, -62, -90, 100, -78, -95, -76, -92, -82, -59, -76, -74, -84, -42, -53, -88, -82, -85;
/M: SY='M';  M= -57, -78, -59, -16, -39, -70,   3,  -1,  -5,  34,  57, -44, -80, -10,  23, -40,  41,  24, -42, -18;
/M: SY='T';  M= -19, -36,  26, -41, -49, -38, -43, -37, -35, -25, -67,   6,  -7, -32, -14,  25,  74,   1,   0,   6;
/M: SY='P';  M=  16, -19, -25,  46,  -4, -38,  -1, -33, -54,  14, -23, -55,  53, -31,  10, -31, -28, -15, -80,   7;
/M: SY='R';  M=  13, -83,  28,  24, -83,  -3, -18, -79,  -2, -54, -23,   4,  38, -10,  42,  -5,   9, -36, -10, -32;
/M: SY='E';  M= -13, -86,  39,  68, -87,  -3,  -6, -61, -38, -47, -75, -32,  19,  48,  -3, -23,  -3, -48, -88, -54;
/M: SY='R';  M= -29, -87, -26, -50, -82,   1, -38, -70,  -5, -30, -70, -19,  18, -18,  96, -19, -28, -40, -85, -73;
/M: SY='R';  M=   4, -84, -33,  -5, -47,   2,  17, -30,  10, -39, -26, -14,  -8,   4,  74,   0, -12, -68,  -4, -16;
/M: SY='R';  M=  20, -82, -10,   1, -66, -15,  27, -29, -11, -24, -68,   3,  26,   9,  54,  -6,  -8,  -9, -85, -20;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2020_04 which contains 563'082 sequence entries.


Total number of hits 25 in 25 different sequences
Number of true positive hits 25 in 25 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Bacteriophages, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] 4Fe-4S Wbl-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
25 sequences

WHB2A_MYCTU (O53353    ), WHB2B_MYCTO (Q7D5T7    ), WHB5A_MYCTU (P71592    ), 
WHB5B_MYCTO (P0DKR7    ), WHB7A_MYCTU (Q6MX01    ), WHB7B_MYCTO (Q8VJ53    ), 
WHIB1_BIFLO (Q8G5J9    ), WHIB1_MYCTO (P9WF42    ), WHIB1_MYCTU (P9WF43    ), 
WHIB2_BIFLO (Q8G5K1    ), WHIB2_MYCS2 (A0QTG3    ), WHIB2_MYCSM (Q9S426    ), 
WHIB3_MYCBO (Q7TWJ2    ), WHIB3_MYCS2 (A0QST8    ), WHIB3_MYCTO (P9WF40    ), 
WHIB3_MYCTU (P9WF41    ), WHIB4_MYCMM (B2HK79    ), WHIB4_MYCTO (P9WF38    ), 
WHIB4_MYCTU (P9WF39    ), WHIB6_MYCTO (P9WF36    ), WHIB6_MYCTU (P9WF37    ), 
WHIB7_MYCS2 (A0QTT1    ), WHIB_BPMT4  (Q9ZX29    ), WHIB_STRCO  (Q7AKN0    ), 
WHID_STRCO  (Q7AKI9    )
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PDB
[Detailed view]
3 PDB

5OAY; 6ONO; 6ONU

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