PROSITE entry PS51849

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General information about the entry

Entry name [info]	RSGI_N
Accession [info]	PS51849
Entry type [info]	MATRIX
Date [info]	31-JAN-2018 CREATED; 26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51849
Associated ProRule [info]	PRU01196

Name and characterization of the entry

Description [info]

RsgI N-terminal anti-sigma domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=48;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=44;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1056739; R2=0.0090989; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4674.6215820; R2=3.0675676; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=978; H_SCORE=7675; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=593; H_SCORE=6494; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M';  M=-25,-22,-16, -6,-10,-10,  7,  0, 26,-15, 37, 30,-26, 12,  4, -8,-15, -9,-30, 33;
/M: SY='K';  M=-25,-39,-20,  0,-30,-34, -5,-29, 62,-25,-26, -2,-30, -4, 46, -9,  9,-24,-38,-17;
/M: SY='G';  M= 17,-37,-28,-36,-44, 80,-34,-46,-29,-44,-35,-15,-31,-29,-38, -9,-24,-28,-38,-40;
/M: SY='I';  M=-23, -2,-45,-41,-14,-48,-43, 60,-32, 15, 24,-37,-39,-36,-27,-29, -1, 43,-41,-21;
/M: SY='V';  M=-14,  0,-47,-42,-16,-48,-48, 49,-39,  4, -4,-41,-41,-40,-41,-31,-17, 65,-46,-24;
/M: SY='M';  M=-22,-14,-47,-40, -1,-46,-32, 31,-37, 36, 69,-40,-40,-32,-36,-35,-19, 34,-37,-10;
/M: SY='E';  M=-15,-41, 24, 63,-44,-32,-18,-43, 32,-34,-33,  2,-24, 16,  3,  5,-20,-38,-43,-33;
/M: SY='I';  M=-20,-25,-36,-23, -7,-42,-12, 43, 15, 13,  3,-25,-36, -7,-12,-10,  1, 32,-39,-18;
/M: SY='K';  M=-17,-39, 18, 27,-27, -8, 24,-35, 39,-31,-24, 25,-29, 15, 11, -1, -2,-28,-42,-14;
/M: SY='K';  M=-18,-40, 18, 22,-37, 30,-11,-44, 41,-41,-33, 22,-17, -6, 19, -5,-12,-40,-42,-32;
/M: SY='K';  M=-25,-40, 28,  6,-35, -2,  9,-42, 39,-37,-20, 37,-18,  3, 35, -3,-12,-39,-44,-18;
/M: SY='Y';  M=-21,-20,-14, -8, 13,-22, 36,-30, 20,-20, -6,  9,-35,  4, 15, 13,  0,-28,  6, 52;
/M: SY='A';  M= 40, 23,-36,-32,-23,-18,-34, 19,-31,  2, 22,-25,-35,-28,-34,  0,  5, 21,  7,-11;
/M: SY='I';  M=-14,-35,-41,-40,-10,-37,-26, 57,-36,  6,  3,-29,-37,-35,-39,-25, 16, 38,-14, 18;
/M: SY='V';  M=-10,-20,-47,-41, -1,-47,-43, 42,-39, 20,  8,-41,-41,-38,-40,-32,-18, 59,-41,-10;
/M: SY='M';  M=-17,-33,-46,-38,  9,-44,-27,  8,-36, 52, 68,-40,-42,-30,-28,-35,-21,  7,-32,  3;
/M: SY='T';  M= -9,  2, -9,-22,-31,-28,-29,-22, -8,-14, -7,  2,-25,-12,-23, 11, 77,-13,-49,-29;
/M: SY='P';  M=  1,-21, 27, 29,-43, -9,-17,-40,  9,-38,-32,  5, 40, 10,  7, 21,-12,-33,-44,-29;
/M: SY='D';  M=-25,-28, 71, 25,-39, -4, -2,-44,  7,-42,-26, 14,-29,  4, -9,  6, -3,-37,-53,-31;
/M: SY='G';  M= -8, 30,-28,-37,-17, 76,-32,-42,-30,-36,-27, -1,-33,-29,-16, -3,-25,-40,-38,-36;
/M: SY='E';  M= -6,-39, 23, 51,-42,-24,-18,-30,  0,-33,-30, -3,-26, 36, 16, 12,  8,-28,-44,-31;
/M: SY='F';  M=-36,-21,-49,-45, 92,-46,-28,  2,-40,  3, -2,-40,-48,-47,-38,-36,-29, -6,  5, 37;
/M: SY='I';  M=-20,-12,-32,-19, -4,-43,  3, 32, 12, 26, 10,-23,-38, -7, 17,-28,-20, 19,-35,  1;
/M: SY='K';  M=-13,-12,-16, 17,-32,-32, -6,-35, 55,-34,-23, 14,-29,  2, 41, -6, -1,-29,-38,-13;
/M: SY='I';  M= -4,-25,-44,-41, -1,-10,-43, 55,-38, 12,  4,-36,-38,-36,-41,-20,-13, 43,-40,-21;
/M: SY='K';  M=-22,-42,-15,-10,-31,-33, -7,-26, 55,-32,-13,  3, 42, -2, 34,-14,-11,-23,-36,  1;
/M: SY='R';  M=-11, -3,-17,-20,-28,-28, -9,-13, 30,  3, -3, 21,  8,-16, 34, -7, 11, -7,-19, -8;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='K';  M=-16,-31, -6,  1,-20, -5, -6,-17, 30,-26,-21, 12,-26,  8, 24, -1,  7,-17,-43,-19; D=-24;
/I:         I=-24; DM=-61;
/M: SY='P';  M= -7,-30, 18, 22,-36,  8, -1,-27, 23,-34,-30, 15, 27, 13, 12, -2, -4,-29,-42,-19;
/M: SY='N';  M=-11,-38, 24,  9,-35, 26,  4,-18,  0,-20,-24, 34, 19,  1, -8,  7, -8,-27,-45,-31;
/M: SY='P';  M=  3, 11,-31,-22,-14,-29, -9,  4,-29,  8, 41,-19, 42,-17,-23,-17,-11, 13, 10, 30;
/M: SY='E';  M= -6,-38,  7, 31,-15,-29,-10,-15, 16,-13,  5,  2,-21, 29, 15,  6, -7,-11,-37,  5;
/M: SY='I';  M=-21,-36,-40,-12,-16,-47,-41, 51,-15, 17, -1,-37, -4,-32,-26,-31,-13, 47,-42,-23;
/M: SY='G';  M=-12,-40,-27,-39,-46, 87,-34,-54,-33,-49,-38, -8,-31,-30,-40, -9,-31,-47,-37,-41;
/M: SY='Q';  M=-15,-42, 31, 52,-43,-33, -7,-37,  6,-31, 10,-11,-26, 58, -3, -5,-15,-30,-42,-20;
/M: SY='E';  M=-17,-41,  2, 71,-38,-38,-12,-16,  8,-24,-24,-16,-23, 20, -8,-15, -4,-10,-42,-19;
/M: SY='I';  M=-13,-19,-45,-42, -1,-41,-39, 61,-35,  5,  4,-38,-28,-36,-40,-29,-11, 40,-33, 21;
/M: SY='E';  M=-18, -8,  7, 31, -4,-32, -1, -4, -7, -6, -8,-18, -1,  5, -7, 11, 14, -4,  8, 18;
/M: SY='F';  M=-20,-29,-43,-41, 64,  6,-32, 23,-34, 10,  0,-32,-30,-39,-32,-26,-20, 17, -6, 26;
/M: SY='P';  M= -7,-38, 18, 22,-14,-21,-11,-17, 14,-16,-25,  8, 29,  2,  0,  4, 20,-23,-40, -7;
/M: SY='P';  M= -8,-40, 20, 36,-31,-31,-16,-22,  2,-11,-21,  4, 43,  2, -4,  5, -6, -6,-43,-15;
/M: SY='K';  M=-13,-38, -8, 20, -7,-19,-18, -8, 28, -5,-11,  4,-13,  8, 11,  8, -6, -1, 10, -1;
/M: SY='D';  M=-11,-38, 41, 18,-26,-17,-21,-28, 28,-26,-13,  9,  2, -1, 11,  6,  2,-10,-44,-18;
/M: SY='I';  M=-10,-37,-26, -3,  0, -9,  9, 27, 10,  5, -6,-13,-14,-14, 18,  2,-10,  9,-15,-18;
/M: SY='R';  M= -9,  4,-17,-19, -3,-21, -3, 15,  2,  1,-10,  9,  3,  3, 23,  3,-10, -3, -2, 18;
/M: SY='K';  M=-14,-26,-19,  1,  9,-22, -4,-11, 25,-17,-16, 19,  3, 10, 24, 13, -1,-11,  3, -8;
/M: SY='R';  M= -5,-38, -5,  3, 11,-10, 15,-20, 19,  2,-20,  8,  7, -6, 20, -5, -7,-11, -1, -1;
/M: SY='R';  M=-13,-38,-21, -1,  4,  1, -9, -8, 18, -8, -6,  4,  3, -3, 19,  9,  0,-13, 19, 17;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	11 in 11 different sequences
Number of true positive hits	11 in 11 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	RsgI N-terminal anti-sigma
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

11 sequences

RSGI1_ACET2 (A3DBH1), RSGI2_ACET2 (A3DC27), RSGI3_ACET2 (A3DC75),

RSGI4_ACET2 (A3DCG3), RSGI5_ACET2 (A3DEX6), RSGI6_ACET2 (A3DH97), 
RSGI7_ACET2 (A3DIE5), RSGI8_ACET2 (A3DJP2), RSGI9_ACET2 (A3DC20), 
RSGI_BACAN  (P0DO99), RSGI_BACSU  (O31655)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

2 PDB

6IVS; 6IVU