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PROSITE entry PS51913


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PURL: https://purl.expasy.org/prosite/signature/PS51913

Direct ScanProsite submission
General information about the entry

Entry name [info] HTH_HARE
Accession [info] PS51913
Entry type [info] MATRIX
Date [info] 22-APR-2020 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51913
Associated ProRule [info] PRU01261

Name and characterization of the entry

Description [info] HARE-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=70;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=65;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1870663; R2=0.0071568; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9651.2480469; R2=2.2973452; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1162; H_SCORE=12321; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=603; H_SCORE=11037; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 98 in 98 different sequences
Number of true positive hits 98 in 98 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] HTH HARE-type
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
98 sequences

ASXL1_HUMAN (Q8IXJ9), ASXL1_MOUSE (P59598), ASXL2_CHICK (Q5ZM88), 
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PDB
[Detailed view]
13 PDB

2KRC; 2M4K; 4NC7; 4NC8; 6ZCA; 6ZFB; 7F75; 8H1T; 8SVF; 8X6G; 8XA6; 8XA7;
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