PROSITE entry PS51926
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General information about the entry
| Entry name [info] | COV_E |
| Accession [info] | PS51926 |
| Entry type [info] | MATRIX |
| Date [info] |
07-OCT-2020 CREATED;
07-OCT-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51926 |
| Associated ProRule [info] | PRU01274 |
Name and characterization of the entry
| Description [info] | Coronavirus envelope (CoV E) protein profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=95; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=90; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=4.5550442; R2=0.0058566; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1016; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=333; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-48; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M=-154,-162,-176,-166,-143,-168,-146,-128,-158,-121, 53,-163,-163,-150,-157,-163,-152,-135,-167,-142; /M: SY='T'; M=-145,-154,-150,-153,-160,-161,-161,-151,-150,-156,-152,-139,-152,-155,-158,-128, 23,-143,-181,-158; /M: SY='F'; M=-168,-164,-181,-176, 30,-176,-160,-141,-172,-133,-143,-169,-179,-182,-169,-167,-160,-147,-133,-111; /M: SY='M'; M= -66, -76, -86, -75, -59, -79, -60, -43, -70, -37, 135, -75, 38, -63, -70, -74, -64, -50, -79, -57; /M: SY='Y'; M= -68, -74, -78, -72, 52, -80, -53, -46, -62, 35, 75, -73, -80, -63, 28, -70, -64, -52, -49, 82; /M: SY='N'; M= 15, -72, 19, 7, -80, -56, -55, -75, -53, -78, -69, 68, 49, 31, -59, 50, -48, -72, -84, -71; /M: SY='F'; M= 7, -71, -82, -74, 69, -78, -70, 12, -75, 60, -40, -78, 25, -74, -75, -70, -62, -44, -61, -43; /M: SY='V'; M= -58, -68, -80, -76, 25, -83, -78, 42, -74, 24, -40, -73, -76, -75, -76, -64, 28, 70, -76, -54; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='W'; M= -58, -79, -74, -70, -70, 2, -74, -64, -70, -5, -66, -64, -78, 23, -73, 67, -57, 16, 81, -65; D=-36; /I: I=-36; DM=-90; /M: SY='F'; M= -68, -78, -65, 46, 53, -84, -67, 43, -66, -2, -53, -69, -73, -64, -71, -65, 35, -49, -65, 32; D=-36; /I: I=-36; DM=-90; /M: SY='E'; M= -64, -77, 55, 71, -69, -66, -48, -79, -46, -76, -70, 66, -65, -44, 12, -54, -57, -76, -76, 39; /M: SY='D'; M= 9, -70, 67, 14, -72, -66, -62, 4, -57, -65, -63, 23, -65, -57, -65, -48, 64, 7, -89, -67; /M: SY='N'; M= -54, -68, -47, -62, -74, 40, -54, -67, -56, -76, -67, 95, -70, -55, -63, 32, 9, 5, -87, -71; /M: SY='G'; M= -54, -75, -69, -75, -66, 78, -74, 7, -69, -10, -61, -57, -70, -68, -75, -53, 34, -3, 75, -64; /M: SY='M'; M= -64, -71, -78, -72, 19, -77, -60, -41, -71, 60, 82, -73, 26, -65, -70, 7, -59, -47, -64, 35; /M: SY='I'; M= 2, -72, -84, -80, 68, -82, -79, 75, -76, -38, -42, -75, -77, -78, -78, -68, -58, 42, -64, -44; /M: SY='V'; M= 1, -68, -78, -75, 29, 4, -76, 26, -73, 23, -44, -71, -76, -73, -75, -62, 8, 63, -74, -55; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='N'; M= -54, -67, -44, -55, -75, -54, -50, -72, -50, -77, -67, 95, -67, 32, -57, 52, 43, -69, -89, -68; /M: SY='C'; M= 3, 57, -76, -74, 16, 5, -76, 55, -72, -48, -49, -66, -74, -70, -75, 28, -53, 47, -76, -59; /M: SY='I'; M= -65, -71, -85, -80, 46, -87, -75, 59, -78, 57, -35, -80, -80, -75, -77, -74, -60, 28, -67, -47; /M: SY='Y'; M= -68, -73, -81, -78, 58, -83, -59, 10, -74, 52, -39, -78, -83, -72, -72, -72, -63, 7, -49, 80; /M: SY='W'; M= -68, -79, -90, -80, 19, -83, -82, 56, -76, 42, -42, -84, -79, -74, -77, -76, -66, 11, 125, -42; /M: SY='F'; M= -65, -70, -83, -79, 77, -84, -73, 37, -76, 41, -40, -76, -80, -77, -76, -69, 10, 30, -61, -40; /M: SY='L'; M= 3, -70, -83, -77, 24, -82, -74, 50, -76, 59, -36, -78, -79, -73, -76, -70, -59, 31, -70, -52; /M: SY='G'; M= 35, -70, -74, -74, -61, 49, -76, 35, -72, 9, -49, -66, -73, -69, -75, -57, -58, 46, -77, -65; /M: SY='C'; M= -65, 92, -82, -79, 73, -80, -72, 23, -76, 39, -46, -73, -83, -77, -77, 0, -61, -47, -64, -44; /M: SY='I'; M= -4, -71, -84, -79, 24, -83, -77, 70, -77, 47, -36, -78, -78, -74, -77, -70, -59, 29, -70, -52; /M: SY='M'; M= 30, -69, -79, -74, 23, 4, -73, 42, -72, 18, 46, -71, -75, -70, -74, -62, -57, 43, -72, -55; /M: SY='F'; M= -65, -69, -83, -78, 70, -84, -72, 22, -76, 52, -39, -76, -80, -76, -75, -70, 10, 33, -63, -42; /M: SY='Y'; M= -64, -72, -77, -75, -37, -82, -60, 26, -72, 53, -38, -74, -79, -68, -71, -67, 17, 28, -57, 79; /M: SY='I'; M= -66, -73, -85, -80, -44, -88, -75, 73, -79, 70, -31, -80, -80, -73, -78, -76, -61, -29, -72, -55; /M: SY='V'; M= -60, -69, -84, -78, 22, -86, -78, 41, -77, 43, -37, -79, -80, -76, -77, -71, -56, 72, -74, -53; /M: SY='G'; M= -50, 43, -65, -69, -70, 67, -69, -63, -66, -7, -62, -53, -69, -64, -72, 44, 35, 6, -80, -70; /M: SY='C'; M= -63, 71, -75, -67, -57, -81, -70, 57, 41, 16, 38, -67, -75, -62, 16, -67, -59, 12, -77, -61; /M: SY='A'; M= 81, -63, -69, -64, -71, 8, -72, -53, -65, -61, -58, -62, -68, -63, -69, -45, 17, 35, -78, -69; /M: SY='F'; M= -69, -71, -86, -80, 76, -86, -70, 31, -78, 67, -35, -80, -83, -77, -76, -76, -64, -40, -59, -39; /M: SY='L'; M= -63, -70, -76, -69, -43, -81, -63, -37, -70, 74, -35, -73, -79, 28, -69, -66, 22, 10, -67, 34; /M: SY='T'; M= 43, -66, -61, -58, -66, -63, -63, -53, 10, 15, -53, 37, -68, 30, -59, -48, 51, 13, -80, -65; /M: SY='C'; M= 35, 72, -78, -74, 67, -70, -72, 42, -72, 0, -50, -69, -77, -72, -74, 11, -57, -45, -65, -47; /M: SY='I'; M= -59, 48, -79, -76, -52, -83, -78, 56, -73, 32, -40, -71, -76, -73, -76, -63, 40, 51, -80, -60; /M: SY='Q'; M= -62, -80, -54, -41, -82, -68, -51, -78, 59, -75, -62, 26, -68, 95, 54, -53, -60, -76, -74, -63; /M: SY='L'; M= 45, 48, -79, -72, 43, -72, -69, -44, -73, 63, -41, -75, -79, -70, -73, -63, -60, -46, -68, -51; /M: SY='C'; M= 27, 124, -79, -76, -63, -73, -79, 18, -74, -9, -55, -70, -82, -76, -78, -61, -58, 30, -88, -71; /M: SY='D'; M= 19, -72, 64, -58, 47, -72, -65, 33, -67, -1, 56, -59, -73, -66, -70, -62, -58, 4, -72, -51; /M: SY='Q'; M= 3, -71, -67, -62, -56, 24, -61, -49, -61, -4, -53, -60, -72, 54, -63, 12, 17, 41, -67, 52; /M: SY='C'; M= -5, 137, -78, -77, -66, -75, -78, -61, -74, -2, -60, -67, -84, -78, -79, -60, 14, 4, -93, -75; /M: SY='C'; M= -63, 130, -76, -74, -61, -77, 72, -62, -73, 25, 37, -65, -84, -71, -73, -66, -62, -60, -92, -63; /M: SY='N'; M= -60, -72, -58, -65, -64, 43, -58, -61, -53, 38, -54, 68, -74, -57, 42, -54, 10, -63, -79, -65; /M: SY='F'; M= 0, 40, -82, -78, 78, -3, -71, 30, -76, 43, -43, -74, -81, -76, -76, -68, -63, -45, -59, -41; /M: SY='W'; M= -61, 98, -83, -79, 17, 15, -80, -48, -75, 16, -54, -74, -82, -77, -78, -67, -63, 40, 102, -53; /M: SY='N'; M= -6, -72, -49, -58, 19, -60, -47, -70, 20, -70, -62, 93, -74, -52, 30, -52, -54, -70, -65, 60; /M: SY='T'; M= -52, -65, -58, -61, -68, 11, -66, -55, 9, -64, -60, 17, -64, -60, -61, 14, 88, 24, -85, -66; /M: SY='W'; M= 3, -74, -79, -72, 21, -70, -77, 5, -69, 19, -52, -71, -74, -67, -72, 28, 14, 18, 123, -45; /M: SY='V'; M= 9, 50, -82, -76, -52, -79, -78, 27, -75, 44, -40, -77, -79, -73, -76, -66, -56, 65, -80, -61; /M: SY='C'; M= 3, 72, -79, -76, -47, -78, -70, 26, -73, 2, -45, -74, -80, -72, -74, -65, -56, 65, -68, 59; /M: SY='K'; M= -58, -72, 26, -51, -67, -70, -63, 10, 57, -3, -55, -52, -67, 24, -49, 13, 42, 18, -80, -63; /M: SY='P'; M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='F'; M= 16, -68, -69, -68, 49, -68, -63, 12, -66, 16, -50, -61, -71, -64, -69, 38, 48, -49, -62, 41; /M: SY='I'; M= 9, -73, -76, -69, 24, 3, -73, 62, -69, -3, -44, -69, -74, 41, -71, -62, -58, 42, -72, -55; /M: SY='Y'; M= -69, -80, -68, -66, -32, -78, 60, 2, 10, -4, -49, -65, -78, -56, 18, -65, -64, -59, -42, 111; /M: SY='V'; M= 14, -68, -70, -69, 21, 11, -69, -40, 9, 32, -47, 24, -76, -66, -66, -60, -56, 55, -74, -57; /M: SY='Y'; M= -68, -79, -67, -72, -24, -75, -40, -52, -64, -53, -50, 24, -82, -61, -63, -64, -62, 12, -34, 126; /M: SY='N'; M= -59, -70, 32, -54, -70, -63, -54, -68, -46, 0, -62, 65, -70, -51, 56, 30, 43, -65, -85, -65; /M: SY='Y'; M= 13, -76, -64, -54, -59, -70, -56, -63, 33, -66, -59, -59, 32, 29, 55, -56, 10, 5, -64, 60; /M: SY='Y'; M= -59, -74, -69, -69, 44, 44, -57, -56, 17, -58, -57, -61, -75, -63, -62, 12, -60, 23, -52, 81; /M: SY='K'; M= -63, -80, -57, -42, -80, -71, -54, -79, 88, -76, -64, -50, -66, 61, 58, -56, -60, -76, -73, -64; /M: SY='N'; M= -59, -74, -47, 13, -71, -60, -50, -75, 13, -77, -67, 79, 33, 33, 19, 34, -51, -74, -76, 23; /M: SY='F'; M= -66, -73, -65, 32, 55, -80, -61, -48, 41, 44, -46, -68, -74, -58, -56, -67, -62, 2, -60, 34; /M: SY='M'; M= -59, -69, -60, -66, -50, -65, -51, -51, -60, 5, 92, 62, -72, -56, -63, 30, 18, -55, -67, 58; /I: I=-25; MD=-63; /M: SY='N'; M= -70, -80, -62, -65, -64, -74, -58, -64, 14, 13, -60, 70, -82, -58, 50, -64, -63, -2, -79, 30; D=-25; /I: I=-25; MD=-63; /M: SY='I'; M= -74, -85, -83, -76, 29, -87, -74, 56, 2, 16, -51, -80, 52, -75, -75, -76, -67, -48, -68, 34; D=-25; /I: I=-25; MD=-63; /M: SY='E'; M= -70, -84, 21, 68, 14, -76, -57, -81, 24, -78, -74, 45, -71, -51, -57, -63, -64, -80, -75, 33; D=-25; /I: I=-25; MD=-63; /M: SY='S'; M= 12, -85, 24, -69, -82, -76, -74, -76, -74, 18, -71, 25, -87, 22, -78, 27, -67, -75, -97, -80; D=-25; /I: I=-25; MD=-63; /M: SY='E'; M= -74, -93, 12, 54, -74, -86, -70, 13, -70, -79, -77, -71, -81, -63, -76, 26, -70, -74, -82, 44; D=-25; /I: I=-25; MD=-63; /M: SY='E'; M= 24, -98, -69, 51,-107, -87, -83,-103, -76,-102, -96, 34, -90, -72, -85, -76, -82, -95,-109,-100; D=-25; /I: I=-25; MI=-63; MD=-63; IM=-63; DM=-63; /M: SY='R'; M= -79, -97, -92, -84, -88, -20, -90, -65, -71, -79, -76, -88, 37, -81, 46, -83, -79, 45,-102, -87; D=-25; /I: I=-25; DM=-63; /M: SY='V'; M= -74, -89, 29, -77, -77, -92, -86, 35, -76, -65, -66, -76, -89, -79, 15, 1, -69, 44,-100, -78; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -77, -98, -85, -78, -90, 14, -88, 8, 2, -82, -77, -82, 80, -81, -83, -78, -75, 1, -94, -89; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= 11, -89, 37, -68, -88, -77, -77, -81, -76, -2, -77, 22, 50, -75, -83, 9, -69, -81, -99, -86; D=-25; /I: I=-25; DM=-63; /M: SY='P'; M= -61, -79, -54, 63, -68, -72, -62, -61, -57, 35, -56, -66, 80, -52, -65, 16, -57, -63, -78, -69; /M: SY='L'; M= -69, -71, -81, -71, 68, -83, -65, -41, -67, 70, -37, -76, -83, 19, 13, -72, -64, -47, -61, -42; /M: SY='P'; M= -12, -81, -58, 51, -76, -71, -68, -57, -59, -68, -63, -69, 99, -58, -68, -61, -57, 37, -81, -75; /I: I=-31; MD=-79; /M: SY='R'; M= -99,-116,-102, -90,-109,-112, -98, -95, 7,-103, -96, -97, 16, -86, 46, -98, -96, 1,-114,-102; D=-31; /I: I=-31; MD=-79; /M: SY='N'; M=-101,-108, 42, -82,-117, -91, -83,-116, -87,-120,-111, 69,-107, -88, -95, -84, -87,-116,-135,-108; D=-31; /I: I=-31; MD=-79; /M: SY='G'; M= -88,-111, 17, 2,-118, 28, -97,-121, -94,-118,-112, -82,-101, -89,-102, 13, -91,-114,-118,-109; D=-31; /I: I=-31; MD=-79; /M: SY='W'; M=-105,-124,-113,-100, -93,-111,-115, 6, 13, -99, -97,-108, 23, -98, -94,-106,-103, -96, 98, -85; D=-31; /I: I=-31; MD=-79; /M: SY='N'; M= -99,-108, 23, -92,-104,-101, -94, 7, -95, -95, -94, 49,-109, -95,-102, -91, -88, -5,-127,-103; D=-31; /I: I=-31; MD=-79; /M: SY='N'; M=-103,-117, -95,-112,-114, 7,-102, 5,-104,-109,-104, 49,-116,-104,-111, -96, -99,-100,-127,-113; D=-31; /I: I=-31; MI=-79; IM=-79; DM=-79; /M: SY='E'; M= -75, -95, 11, 56, -99, -85, -71, -98, 36, -94, -87, -66, -78, 32, -60, 8, -73, -93, -96, -86; /M: SY='N'; M= -79, -86, -70, -82, -70, -82, -70, -1, -75, -10, -70, 66, -89, -76, -81, -67, 42, -71, -88, 38; /M: SY='L'; M= -79, -89, -99, -92, -67,-101, -94, 31, -92, 36, -54, -96, 22, -90, -94, -89, -75, 35, -94, -76; /I: I=-23; MD=-58; /M: SY='C'; M= 22, 44,-132,-126,-135,-116,-133,-129,-127,-128,-124,-124,-133,-126,-132,-107,-115,-116,-143,-135; D=-23; /I: I=-23; MI=0; MD=-58; IM=0; DM=-58; /M: SY='D'; M=-127,-136, 10,-118,-115,-140,-128, 4,-130, -13,-103,-121,-135,-127,-134,-129,-120,-100,-141,-120; D=-23; /I: I=-23; DM=-58; /M: SY='Y'; M=-128,-137, 14,-110,-110,-123,-104,-132,-116,-132,-126, 17,-135,-115,-121,-115,-117,-134,-121, 27; D=-23; /I: I=-23; DM=-58; /M: SY='V'; M=-100,-117,-123,-121,-105,-122,-126, 7,-119, -92, -94,-115,-122,-116,-122, 3, -96, 26,-131,-110; /I: I=-23; E1=0; IE=-380; DE=-58;» more |
Numerical results [info]
| Total number of hits | 46 in 46 different sequences |
| Number of true positive hits | 46 in 46 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
46 sequences
VEMP_BC133 (Q0Q4E8), VEMP_BC279 (Q0Q473), VEMP_BC512 (Q0Q464), VEMP_BCHK3 (Q3LZW9), VEMP_BCHK4 (A3EX99), VEMP_BCHK5 (A3EXD5), VEMP_BCHK9 (A3EXG8), VEMP_BCRP3 (Q3I5J3), VEMP_CVBEN (P0C2Q1), VEMP_CVBF (P15775), VEMP_CVBLS (P0C2Q2), VEMP_CVBLU (P0C2Q3), VEMP_CVBLY (P0C2Q4), VEMP_CVBM (P15779), VEMP_CVBOK (P0C2Q5), VEMP_CVBON (P0C2Q6), VEMP_CVBQ (P0C2Q7), VEMP_CVCAI (P36696), VEMP_CVCBG (Q7T6T0), VEMP_CVH22 (P19741), VEMP_CVHN1 (Q5MQC8), VEMP_CVHN2 (Q14EA8), VEMP_CVHN5 (Q0ZME5), VEMP_CVHNL (Q6Q1S0), VEMP_CVHOC (Q04854), VEMP_CVMA5 (P0C2R0), VEMP_CVMJH (P06591), VEMP_CVMS (P29076), VEMP_CVP67 (P0C2Q8), VEMP_CVPFS (P22655), VEMP_CVPIA (P0C2Q9), VEMP_CVPPU (P09048), VEMP_CVPR8 (P69611), VEMP_CVPRM (P69610), VEMP_CVRSD (Q9IKC8), VEMP_FIPV (Q52PA5), VEMP_IBVB (Q89894), VEMP_IBVK (P19744), VEMP_IBVM (P05139), VEMP_IBVP3 (P30246), VEMP_IBVU4 (P30247), VEMP_IBVU5 (P30248), VEMP_MERS1 (K9N5R3), VEMP_PEDV7 (Q84706), VEMP_SARS (P59637), VEMP_SARS2 (P0DTC4)» more
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| PDB [Detailed view] |
13 PDB
2MM4; 5X29; 5XER; 5XES; 7K3G; 7M4R; 7NTJ; 7QCR; 7QCS; 7QCT; 7TV0; 8SUZ; 8U1T » more |