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PROSITE entry PS52030


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General information about the entry

Entry name [info] SMDRR
Accession [info] PS52030
Entry type [info] MATRIX
Date [info] 08-NOV-2023 CREATED;
08-NOV-2023 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52028
Associated ProRule [info] PRU01374

Name and characterization of the entry

Description [info] Streptococcal M proteins D repeats region profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=27;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=25;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2162844; R2=0.0092737; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=786; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=570; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-6; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='E';  M=  4,  4,-25,  7, 35,-28,-15, -6,-25, 12,-19,-16, -2, -4, 11,  1,  1, -8,-21,-26,-18, 23;
/M: SY='R';  M=  7, -7,-23,-11, -1,-23,-13, -9,-23, 21,-19,-10, -3,-14,  3, 29, -3, -7,-13,-20,-13, -1;
/M: SY='L';  M= -9,-30,-21,-32,-23,  7,-32,-23, 27,-29, 38, 19,-28,-28,-21,-22,-25, -9, 20,-21, -1,-23;
/M: SY='E';  M=-10,  5,-30, 10, 34,-30,-20, -5,-30, 31,-25,-15,  0, -5, 15, 16, -5,-10,-25,-25,-15, 24;
/M: SY='V';  M= 24,-20,-10,-25,-20,-10,-16,-25, 11,-15,  0,  0,-20,-20,-20,-20,  0,  0, 26,-25,-15,-20;
/M: SY='E';  M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='N';  M= 19, 16,-15,  1, -5,-20,  0, -4,-15, -5,-20,-15, 26,-15, -5,-10, 10,  0,-16,-30,-20, -5;
/M: SY='A';  M= 21, -5,-20,-10,  0,-25,-10,-15,-20, 19,-20,-10, -5,-10,  0,  4,  0, -5,-10,-20,-15,  0;
/M: SY='K';  M= 19, -5,-20,-10,  0,-25,-10,-15,-20, 21,-20,-10, -5,-10,  0,  6,  0, -5,-10,-20,-15,  0;
/M: SY='Y';  M=-15,-25,-25,-25,-20, 20,-30,  1, 10,-20, 24, 10,-25,-30,-15,-15,-25,-10,  0,  6, 42,-20;
/M: SY='K';  M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='E';  M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='Q';  M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='A';  M= 40,-14,-10,-22,-14,-16, -6,-22, -2,-12, -6, -6,-14,-14,-14,-20,  6,  0, 10,-22,-18,-14;
/M: SY='K';  M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='Q';  M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='E';  M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='E';  M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='E';  M= 19,  0,-20,  1, 26,-25,-10,-10,-20,  0,-15,-15, -5, -5,  6,-10,  5, -5,-16,-25,-20, 16;
/M: SY='K';  M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='A';  M= 21,-20,-15,-25,-15, -6,-14,-20,  4,-20, 19,  4,-20,-20,-15,-20, -9, -5,  5,-20,-10,-15;
/M: SY='K';  M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='A';  M= 39,-10,-15,-18,-12,-22, 16,-20,-17,-12,-15,-12, -8,-12,-12,-20,  8, -5, -7,-20,-22,-12;
/M: SY='E';  M=-13, 27,-28, 33, 36,-30,-13,  2,-30,  5,-25,-23, 19, -7, 10, -3,  2, -8,-30,-35,-20, 23;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] REPEAT
Feature description [info] D
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

ARP4_STRPY  (P13050), M12_STRPY   (P19401), M21_STRPY   (P50468), 
M22_STRPY   (P50469), M24_STRPY   (P12379), M49_STRP9   (P16947), 
M5_STRP5(P02977), M6A_STRP6   (Q5X9Q9), M6B_STRPY   (P08089), 
MRP4_STRPY  (P30141), MX_STRP9(P16946), PAM_STRPY   (P49054), 
SPH_STRP1   (P50470)
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PDB
[Detailed view]
1 PDB

8SKV