PRU01374
General rule information
[?]
Accession | PRU01374 |
Dates | 5-JUL-2023 (Created) 5-JUL-2023 (Last updated, Version 1) |
Data class | Domain |
Predictors | PROSITE; PS52030; SMDRR |
Name | Streptococcal M proteins D repeat |
Function | M proteins belong to a family of fibrous streptococcal surface proteins which represent major virulence factors due to their antiphagocytic activities. All M proteins share a common framework that includes a conserved signal peptide, a hypervariable amino terminus, a less variable central domain, and a highly conserved C-terminus. A number of repeat sequences (A, B, C and D repeats) follow the hypervariable region. Sequence conservation increases from the A repeats to D repeats. |
Propagated annotation
[?]
Comments
[?]
Subcellular location | Secreted, cell wall; Peptidoglycan-anchor. |
Similarity | Belongs to the M protein family. |
Gene Ontology
[?]
GO:0005576; Cellular component: extracellular region.
Keywords
[?]
Features
[?]
From: PS52030 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REPEAT | from | 6 | D # | |||||||||
REPEAT | 7 | 12 | D # | |||||||||
REPEAT | 15 | 20 | D # | |||||||||
REPEAT | 22 | to | D # |
Additional information
[?]
Size range | 27-27 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q5X9Q9 (M6A_STRP6) |
Scope | Bacteria; Streptococcus |
Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.