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PROSITE entry PS52020


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS52020
Entry name [info] CRESS_DNA_REP
Accession [info] PS52020
Entry type [info] MATRIX
Date [info] 28-JUN-2023 CREATED;
28-JUN-2023 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC52020
Associated ProRule [info] PRU01364

Name and characterization of the entry

Description [info] CRESS-DNA virus replication initiator protein (Rep) endonuclease domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=101;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=96;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4021773; R2=0.0249368; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=385; N_SCORE=12.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=165; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 72 in 72 different sequences
Number of true positive hits 72 in 72 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CRESS-DNA virus Rep endonuclease
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
72 sequences

MREP_BBTVA  (Q86567), MREP_FBNY1  (Q9WIJ5), MREP_FBNY2  (O39828), 
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PDB
[Detailed view]
11 PDB

1L2M; 1L5I; 2HW0; 2HWT; 6H8O; 6Q1M; 6WDZ; 6WE0; 6WE1; 7KIK; 8H56