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PRU00264


General rule information [?]

Accession PRU00264
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 14)
Data class Domain
Predictors PROSITE; PS50064; ZF_PARP_2
Name Zinc finger poly(ADP-ribose) polymerase (PARP)-type
Function Bind specifically to single-stranded DNA

Propagated annotation [?]


Cross-references [?]

PROSITE PS00347; ZF_PARP_1; 1;

Comments [?]

Subcellular location Nucleus.

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.

Keywords [?]

Nucleus
DNA-binding
Zinc-finger
case <Feature:PS50064:13=[CH]> and <Feature:PS50064:16=[CH]> and <Feature:PS50064:47=[CH]> and <Feature:PS50064:50=[CH]>
Zinc
Metal-binding
end case


Features [?]

case <Feature:PS50064:13=[C]> and <Feature:PS50064:16=[C]> and <Feature:PS50064:47=[H]> and <Feature:PS50064:50=[C]>
From: PS50064
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     to       PARP-type #        
else case <Feature:PS50064:13=[CH]> and <Feature:PS50064:16=[CH]> and <Feature:PS50064:47=[CH]> and <Feature:PS50064:50=[CH]>
ZN_FING     from     to       PARP-type #; atypical        
else
ZN_FING     from     to       PARP-type #; degenerate        
end case

BINDING     13     13       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     16     16       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     47     47       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1
BINDING     50     50       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1     [CH]   1

Additional information [?]

Size range 83-93 amino acids
Related rules None
Repeats 1-2
Topology Undefined
Example P35875 (PARP_DROME)
Scope
Eukaryota

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]