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ProRule PRU00264


General rule information [?]

Accession PRU00264
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 14)
Data class Domain;
Predictors PROSITE; PS50064; ZF_PARP_2
Name Zinc finger poly(ADP-ribose) polymerase (PARP)-type
Function Bind specifically to single-stranded DNA
Scope(s) Eukaryota
Example(s) P35875 (PARP_DROME);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Nucleus
DNA-binding
Zinc-finger
case <Feature:PS50064:13=[CH]> and <Feature:PS50064:16=[CH]> and <Feature:PS50064:47=[CH]> and <Feature:PS50064:50=[CH]>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus

Cross-references [?]

PROSITE PS00347; ZF_PARP_1; 1;

Features [?]

From: PS50064
Key From To Description Tag Condition FTGroup
case <Feature:PS50064:13=[C]> and <Feature:PS50064:16=[C]> and <Feature:PS50064:47=[H]> and <Feature:PS50064:50=[C]>
ZN_FING from to /note="PARP-type #"
else case <Feature:PS50064:13=[CH]> and <Feature:PS50064:16=[CH]> and <Feature:PS50064:47=[CH]> and <Feature:PS50064:50=[CH]>
ZN_FING from to /note="PARP-type #; atypical"
else
ZN_FING from to /note="PARP-type #; degenerate"
end case
BINDING 13 13 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 16 16 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 47 47 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1
BINDING 50 50 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"
[CH] 1

Additional information [?]

Size range 83-93 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]