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annotation rule: PRU00267

General rule information [?]

Accession PRU00267
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 14)
Data class Domain
Predictors PROSITE; PS50118; HMG_BOX_2
Name HMG boxes A and B DNA-binding domains
Function Bind preferentially to distorted DNAs
case not <Triggered>

Propagated annotation [?]

Comments [?]

end case

Subcellular location Nucleus.

Cross-references [?]

PROSITE PS00353; HMG_BOX_1; 0-1;

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.

Keywords [?]

Features [?]

From: PS50118
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     from     to       HMG box #        

Additional information [?]

case <Feature:PS00353==0>
Warning If the entry belongs to the HMG1/HMG2 protein family, it should contain DR PROSITE; PS00353; HMG_BOX_1;
end case

Size range 44-81 amino acids
Related rules None
Repeats 1-6
Topology Undefined
Example Q24537 (HMG2_DROME)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]