General rule information
[?]
Accession |
PRU00272 |
Dates |
12-DEC-2003 (Created) 21-NOV-2019 (Last updated, Version 13) |
Predictors |
PROSITE; PS50830; TNASE_3
|
Name |
Thermonuclease domain |
Function |
catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond yielding 3'-mononucleotides and dinucleotides |
Propagated annotation
[?]
case (<OC:Bacteria> or <OC:Archaea>) and <Length<240>
Similarity |
Belongs to the thermonuclease family. |
end case
case <FTGroup:1>
GO:0005509; Molecular function: calcium ion binding.
end case
case <FTGroup:2>
GO:0016787; Molecular function: hydrolase activity.
end case
case <FTGroup:1>
end case
case <FTGroup:2>
end case
From: PS50830 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
TNase-like #
|
|
|
|
|
|
|
METAL
|
|
14
|
|
14
|
|
Calcium
|
|
|
|
D
|
|
1
|
METAL
|
|
33
|
|
33
|
|
Calcium
|
|
|
|
D
|
|
1
|
METAL
|
|
34
|
|
34
|
|
Calcium; via carbonyl oxygen
|
|
|
|
T
|
|
1
|
ACT_SITE
|
|
28
|
|
28
|
|
|
|
|
|
R
|
|
2
|
ACT_SITE
|
|
36
|
|
36
|
|
|
|
|
|
E
|
|
2
|
ACT_SITE
|
|
79
|
|
79
|
|
|
|
|
|
R
|
|
2
|
Additional information
[?]
Size range |
119-209 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Examples |
P22997 (PARB4_ECOLX); Q7KZF4 (SND1_HUMAN): [Recover all] |
Scope |
Eukaryota
Bacteria
Archaea |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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