PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00322


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00322
General rule information [?]

Accession PRU00322
Dates 01-MAR-2004 (Created)
19-NOV-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS50199; ZF_RANBP2_2
Name Zinc finger RanBP2-type
Function It has been shown that RanBP2-type zinc fingers bind RanGDP (but not RanGTP) and the exportin-1 protein (a receptor of the export pathway).
Scope(s) Eukaryota
Example(s) P49792;

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>
Zinc
Metal-binding
end case
case <Feature:PS50199:7=C> and <Feature:PS50199:10=C> and <Feature:PS50199:21=C> and <Feature:PS50199:24=C>
else case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>

Cross-references [?]

PROSITE PS01358; ZF_RANBP2_1; 1;

Features [?]

From: PS50199
Key From To Description Tag Condition FTGroup
case <Feature:PS50199:7=C> and <Feature:PS50199:10=C> and <Feature:PS50199:21=C> and <Feature:PS50199:24=C>
ZN_FING from to /note="RanBP2-type #"
else case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>
ZN_FING from to /note="RanBP2-type #; atypical"
else
ZN_FING from to /note="RanBP2-type #; degenerate"
end case
BINDING 7 7 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 21 21 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 24 24 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 30-35 amino acids
Related rules None
Fusion None
Repeats 8
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]