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ProRule PRU00322


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PURL: https://purl.expasy.org/prosite/rule/PRU00322
General rule information [?]

Accession PRU00322
Dates 01-MAR-2004 (Created)
19-NOV-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS50199; ZF_RANBP2_2
Name Zinc finger RanBP2-type
Function It has been shown that RanBP2-type zinc fingers bind RanGDP (but not RanGTP) and the exportin-1 protein (a receptor of the export pathway).
Scope(s) Eukaryota
Example(s) P49792 (RBP2_HUMAN);

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>
Zinc
Metal-binding
end case
case <Feature:PS50199:7=C> and <Feature:PS50199:10=C> and <Feature:PS50199:21=C> and <Feature:PS50199:24=C>
else case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>

Cross-references [?]

PROSITE PS01358; ZF_RANBP2_1; 1;

Features [?]

From: PS50199
Key From To Description Tag Condition FTGroup
case <Feature:PS50199:7=C> and <Feature:PS50199:10=C> and <Feature:PS50199:21=C> and <Feature:PS50199:24=C>
ZN_FING from to /note="RanBP2-type #"
else case <Feature:PS50199:7=[CH]> and <Feature:PS50199:10=[CH]> and <Feature:PS50199:21=[CH]> and <Feature:PS50199:24=[CH]>
ZN_FING from to /note="RanBP2-type #; atypical"
else
ZN_FING from to /note="RanBP2-type #; degenerate"
end case
BINDING 7 7 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 21 21 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 24 24 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 30-35 amino acids
Related rules None
Fusion None
Repeats 8
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]