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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00335


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00335
General rule information [?]

Accession PRU00335
Dates 07-APR-2004 (Created)
21-NOV-2019 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS50977; HTH_TETR_2
Name TetR-type HTH domain
Function The tetR-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 60 residues present in the tetR family of prokaryotic transcription regulators.
Scope(s) Bacteria
Archaea
Example(s) P0ACT4;

Propagated annotation [?]

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function:DNA binding

Cross-references [?]

PROSITE PS01081; HTH_TETR_1; 1;

Features [?]

From: PS50977
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HTH tetR-type #"
DNA_BIND 24 43 /note="H-T-H motif"

Additional information [?]

Size range 54-67 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]