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annotation rule: PRU00381

General rule information [?]

Accession PRU00381
Dates 6-JAN-2005 (Created)
16-DEC-2016 (Last updated, Version 9)
Data class Domain
Predictors PROSITE; PS51057; PAIRED_2
Name Paired domain
Function The paired domain is a ~126 amino acid DNA-binding domain, which is found in eukaryotic transcription regulatory proteins involved in embryogenesis.

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.

Cross-references [?]


Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.

Keywords [?]

Features [?]

From: PS51057
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Paired #        

Additional information [?]

Size range 120-140 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example P63016 (PAX6_RAT)
Eukaryota; Metazoa


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]