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ProRule PRU00472


General rule information [?]

Accession PRU00472
Dates 10-AUG-2005 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51133; ZF_TFIIS_2
Name Zinc finger TFIIS-type
Function involved in RNA cleavages when pol II is blocked by backtracking
Scope(s) Eukaryota
Viruses
Archaea
Example(s) P07273 (TFS2_YEAST);

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <Feature:PS51133:5=[CH]> and <Feature:PS51133:8=[CH]> and <Feature:PS51133:33=[CH]> and <Feature:PS51133:36=[CH]>
GO:0046872; Molecular function:metal ion binding
GO:0008270; Molecular function:zinc ion binding

Cross-references [?]

PROSITE PS00466; ZF_TFIIS_1; 1;

Features [?]

From: PS51133
Key From To Description Tag Condition FTGroup
case <Feature:PS51133:5=C> and <Feature:PS51133:8=C> and <Feature:PS51133:33=C> and <Feature:PS51133:36=C>
ZN_FING from to /note="TFIIS-type #"
else case <Feature:PS51133:5=[CH]> and <Feature:PS51133:8=[CH]> and <Feature:PS51133:33=[CH]> and <Feature:PS51133:36=[CH]>
ZN_FING from to /note="TFIIS-type #; atypical"
else
ZN_FING from to /note="TFIIS-type #; degenerate"
end case
BINDING 5 5 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 8 8 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 33 33 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 36 36 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 39-42 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]