We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00490
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00490
General rule information
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| Accession | PRU00490 |
| Dates | 31-OCT-2005 (Created)
24-SEP-2020 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51154; MACRO PROSITE; PS51940; SARS_NSP3C_N PROSITE; PS51941; BCOV_NSP3C_M |
Name | Macro domain |
| Function | The Macro domain is a module of ~180 amino acids which can bind ADP-ribose, an NAD metabolite or related ligands. |
| Scope(s) |
Eukaryota Bacteria Archaea Viruses |
| Example(s) | Q8IXQ6; |
Propagated annotation
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Features
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| From: any | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | entry | exit | /note="Macro #" | |||||||||
Additional information
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| Size range | 140-210 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-3 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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