ProRule PRU00593
General rule information
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| Accession | PRU00593 |
| Dates | 17-OCT-2006 (Created)
27-JUN-2022 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS01124; HTH_ARAC_FAMILY_2 |
Name | araC/xylS-type HTH domain |
| Function | The araC/xylS-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 100 amino acids, present in bacterial transcription regulators of genes involved in resistance to antibiotics, organic solvents and heavy metals. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P0ACH5 (MARA_ECOLI); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Cross-references
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| PROSITE | PS00041; HTH_ARAC_FAMILY_1; 1; |
Features
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| From: PS01124 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH araC/xylS-type #" | |||||||||
| DNA_BIND | 18 | 39 | /note="H-T-H motif" | |||||||||
| DNA_BIND | 66 | 89 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 80-120 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [262] All [ 262 ]
- Retrieve set of proteins with 3D structure for this domain