ProRule PRU00653
General rule information
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Accession | PRU00653 |
Dates | 5-DEC-2007 (Created)
23-JAN-2023 (Last updated, Version 4) |
Data class | Domain; |
Predictors |
PROSITE; PS51323; IGFBP_N_2 |
Name | Insulin-like growth factor binding protein N-terminal domain |
Function | The IGFBP N-terminal domain participates in binding to IGFs. |
Scope(s) |
Eukaryota Metazoa |
Example(s) | P48745 (CCN3_HUMAN); |
Propagated annotation
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Keywords
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case <FTTag:disulf> | |
Disulfide bond | |
end case |
Cross-references
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PROSITE | PS00222; IGFBP_N_1; 1; |
Features
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From: PS51323 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="IGFBP N-terminal #" | |||||||||
case <Feature:PS51323:31-32=C-C> | ||||||||||||
DISULFID | 5 | 29 | disulf | C-x*-C | ||||||||
DISULFID | 8 | 31 | disulf | C-x*-C | ||||||||
DISULFID | 13 | 32 | disulf | C-x*-C | ||||||||
DISULFID | 20 | 35 | disulf | C-x*-C | ||||||||
DISULFID | 43 | 56 | disulf | C-x*-C | ||||||||
DISULFID | 50 | 76 | disulf | C-x*-C | ||||||||
else | ||||||||||||
DISULFID | 5 | 8 | disulf | C-x*-C | ||||||||
DISULFID | 13 | 20 | disulf | C-x*-C | ||||||||
DISULFID | 29 | 35 | disulf | C-x*-C | ||||||||
DISULFID | 43 | 56 | disulf | C-x*-C | ||||||||
DISULFID | 50 | 76 | disulf | C-x*-C | ||||||||
end case |
Additional information
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Size range | 60-100 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [99] All [ 99 ]
- Retrieve set of proteins with 3D structure for this domain