PRU00653

General rule information [?]

Accession	PRU00653
Dates	5-DEC-2007 (Created) 23-JAN-2023 (Last updated, Version 4)

Data class

Domain

Predictors

PROSITE; PS51323; IGFBP_N_2

Names

Insulin-like growth factor binding protein N-terminal domain; IGFBP N-terminal domain

Function

The IGFBP N-terminal domain participates in binding to IGFs.

Propagated annotation [?]

Cross-references [?]

PROSITE

PS00222; IGFBP_N_1; 1;

Keywords [?]

case <FTTag:disulf>

Disulfide bond

end case

Features [?]

From: PS51323

Key From To Description Tag Condition FTGroup

DOMAIN from to IGFBP N-terminal #

case <Feature:PS51323:31-32=C-C>

DISULFID 5 29 disulf C-x*-C

DISULFID 8 31 disulf C-x*-C

DISULFID 13 32 disulf C-x*-C

DISULFID 20 35 disulf C-x*-C

DISULFID 43 56 disulf C-x*-C

DISULFID 50 76 disulf C-x*-C

else

DISULFID 5 8 disulf C-x*-C

DISULFID 13 20 disulf C-x*-C

DISULFID 29 35 disulf C-x*-C

DISULFID 43 56 disulf C-x*-C

DISULFID 50 76 disulf C-x*-C

end case

Additional information [?]

Size range	60-100 amino acids
Related rules	None
Repeats	1
Topology	Not cytoplasmic
Example	P48745 (CCN3_HUMAN)
Scope	Eukaryota; Metazoa

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Eukaryota [99]
Retrieve set of proteins with 3D structure for this domain