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annotation rule: PRU01035

General rule information [?]

Accession PRU01035
Dates 22-AUG-2014 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS50235; USP_3
Name Ubiquitin specific protease (USP) domain
Function The USP domain forms the peptidase family C19.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the peptidase C19 family.

Cross-references [?]

PROSITE PS00972; USP_1; 1;
PS00973; USP_2; 1;

Gene Ontology [?]

case <FTGroup:1>
GO:0006511; Biological process: ubiquitin-dependent protein catabolic process.

Keywords [?]

Hydrolase
Protease
Thiol protease
end case

Ubl conjugation pathway

Features [?]

From: PS50235
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       USP #        
ACT_SITE     10     10       Nucleophile     C   1
ACT_SITE     288     288       Proton acceptor     H   1

Additional information [?]

Size range 94-892 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P39967 (UBP9_YEAST)
Scope
Eukaryota
Viruses; Mimivirus
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]