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annotation rule: PRU01172

General rule information [?]

Accession PRU01172
Dates 1-FEB-2017 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51828; PTX_2
Name Pentraxin (PTX) domain
Function Pentraxins (earlier also termed pentaxins), named for their homopentameric quaternary structure, are a superfamily of multifunctional conserved proteins that are characterized by a cyclic multimeric structure and by the presence in their carboxyl-terminal of an ~200 aa-long conserved domain, called pentraxin (PTX) domain.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00289; PTX_1; 1;

Keywords [?]

case <FTGroup:1> or <FTGroup:2>
Calcium
Metal-binding
end case

case <FTTag:disulf>
Disulfide bond
end case


Features [?]

From: PS51828
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Pentraxin (PTX) #        
METAL     54     54       Calcium #1     D   1
METAL     55     55       Calcium #1     N   1
METAL     133     133       Calcium #1     E   1
METAL     133     133       Calcium #2     E   2
METAL     134     134       Calcium #1; via carbonyl oxygen     Q   1
METAL     135     135       Calcium #1     D   1
METAL     135     135       Calcium #2     D   2
METAL     145     145       Calcium #2     Q   2
DISULFID     32     91           disulf   C-x*-C  

Additional information [?]

Size range 12-222 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q6QNK2 (AGRD1_HUMAN)
Scope
Eukaryota; Metazoa
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]