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annotation rule: PRU01240

General rule information [?]

Accession PRU01240
Dates 23-MAY-2019 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51892; SUBTILASE
Name Serine proteases, subtilase domain
Function Subtilases are an extensive family of serine proteases which occur in Archaea, Bacteria, fungi, yeasts, and higher eukaryotes. Their catalytic activity is provided by a charge relay system similar to that of the trypsin family of serine proteases but which evolved by independent convergent evolution.

Propagated annotation [?]


Cross-references [?]

case <FT:2>
PROSITE PS00136; SUBTILASE_ASP; 1;
end case

case <FT:3>
PROSITE PS00137; SUBTILASE_HIS; 1;
end case

case <FT:4>
PROSITE PS00138; SUBTILASE_SER; 1;
end case


Comments [?]

Similarity Belongs to the peptidase S8 family.

Gene Ontology [?]

case <FTGroup:1>
GO:0004252; Molecular function: serine-type endopeptidase activity.

Keywords [?]

Hydrolase
Protease
Serine protease
end case


Features [?]

From: PS51892
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase S8        
ACT_SITE     31     31       Charge relay system     D   1
ACT_SITE     66     66       Charge relay system     H   1
ACT_SITE     230     230       Charge relay system     S   1

Additional information [?]

Size range 240-560 amino acids
Related rules None
Repeats 1
Topology Undefined
Example B8N106 (ORYZ_ASPFN)
Scope
Eukaryota
Bacteria
Archaea; Euryarchaeota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]