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annotation rule: PRU01240 |
Accession | PRU01240 |
Dates | 23-MAY-2019 (Created) 22-NOV-2019 (Last updated, Version 2) |
Data class | Domain |
Predictors | PROSITE; PS51892; SUBTILASE |
Name | Serine proteases, subtilase domain |
Function | Subtilases are an extensive family of serine proteases which occur in Archaea, Bacteria, fungi, yeasts, and higher eukaryotes. Their catalytic activity is provided by a charge relay system similar to that of the trypsin family of serine proteases but which evolved by independent convergent evolution. |
PROSITE | PS00136; SUBTILASE_ASP; 1; |
PROSITE | PS00137; SUBTILASE_HIS; 1; |
PROSITE | PS00138; SUBTILASE_SER; 1; |
Similarity | Belongs to the peptidase S8 family. |
From: PS51892 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | Peptidase S8 | |||||||||
ACT_SITE | 31 | 31 | Charge relay system | D | 1 | |||||||
ACT_SITE | 66 | 66 | Charge relay system | H | 1 | |||||||
ACT_SITE | 230 | 230 | Charge relay system | S | 1 |
Size range | 240-560 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | B8N106 (ORYZ_ASPFN) |
Scope | Eukaryota
Bacteria
Archaea; Euryarchaeota |
Comments | None |