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ProRule PRU01240


General rule information [?]

Accession PRU01240
Dates 23-MAY-2019 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51892; SUBTILASE
Name Serine proteases, subtilase domain
Function Subtilases are an extensive family of serine proteases which occur in Archaea, Bacteria, fungi, yeasts, and higher eukaryotes. Their catalytic activity is provided by a charge relay system similar to that of the trypsin family of serine proteases but which evolved by independent convergent evolution.
Scope(s) Eukaryota
Bacteria
Archaea
Euryarchaeota
Example(s) B8N106 (ORYZ_ASPFN);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the peptidase S8 family.

Keywords [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0004252; Molecular function:serine-type endopeptidase activity

Cross-references [?]

PROSITE PS00136; SUBTILASE_ASP; 1;
PROSITE PS00137; SUBTILASE_HIS; 1;
PROSITE PS00138; SUBTILASE_SER; 1;

Features [?]

From: PS51892
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase S8"
ACT_SITE 31 31 /note="Charge relay system" D 1
ACT_SITE 66 66 /note="Charge relay system" H 1
ACT_SITE 230 230 /note="Charge relay system" S 1

Additional information [?]

Size range 240-560 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]