General rule information
[?]
Accession |
PRU01298 |
Dates |
6-JAN-2021 (Created) 12-JAN-2021 (Last updated, Version 2) |
Predictors |
PROSITE; PS51953; NIV_EXON
|
Name |
Nidovirus 3'-5' exoribonuclease (ExoN) domain |
Function |
The nidovirus 3'-5' exoribonuclease (ExoN) domain may enhance the fidelity of RNA synthesis by correcting nucleotide incorporation errors made by the RNA-dependent RNA polymerase. |
Propagated annotation
[?]
case <FTGroup:1>
GO:0004527; Molecular function: exonuclease activity.
end case
case <FTGroup:2> or <FTGroup:3>
GO:0008270; Molecular function: zinc ion binding.
GO:0046872; Molecular function: metal ion binding.
end case
case <FTGroup:1>
end case
From: PS51953 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
ExoN #
|
|
|
|
|
|
|
ACT_SITE
|
|
19
|
|
19
|
|
|
|
|
|
D
|
|
1
|
ACT_SITE
|
|
21
|
|
21
|
|
|
|
|
|
E
|
|
1
|
ACT_SITE
|
|
120
|
|
120
|
|
|
|
|
|
[ED]
|
|
1
|
ACT_SITE
|
|
198
|
|
198
|
|
|
|
|
|
H
|
|
1
|
ACT_SITE
|
|
203
|
|
203
|
|
|
|
|
|
D
|
|
1
|
METAL
|
|
136
|
|
136
|
|
Zinc #1
|
|
|
|
C
|
|
2
|
METAL
|
|
139
|
|
139
|
|
Zinc #1
|
|
|
|
C
|
|
2
|
METAL
|
|
155
|
|
155
|
|
Zinc #1
|
|
|
|
C
|
|
2
|
METAL
|
|
158
|
|
158
|
|
Zinc #1
|
|
|
|
H
|
|
2
|
METAL
|
|
186
|
|
186
|
|
Zinc #2
|
|
|
|
H
|
|
3
|
METAL
|
|
190
|
|
190
|
|
Zinc #2
|
|
|
|
C
|
|
3
|
METAL
|
|
194
|
|
194
|
|
Zinc #2
|
|
|
|
H
|
|
3
|
METAL
|
|
209
|
|
209
|
|
Zinc #2
|
|
|
|
C
|
|
3
|
Additional information
[?]
Size range |
230-265 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
P0C6Y1 (R1AB_IBVB) |
Scope |
Viruses; Nidovirales |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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