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annotation rule: PRU01303 |
Accession | PRU01303 |
Dates | 27-JAN-2021 (Created) 27-JAN-2021 (Last updated, Version 2) |
Data class | Domain |
Predictors | PROSITE; PS51958; NENDOU |
Name | Nidoviral uridylate-specific endoribonuclease (NendoU) domain |
Function | Among the Nsps found in Nidovirales, nonstructural protein 15 (nsp15) from coronaviruses and Nsp11 from arteriviruses contain in their C- terminal region a conserved endoribonuclease domain called nidoviral uridylate-specific endoribonuclease (NendoU) with cleavage specificity for single- and double-stranded RNA 5' of uridine nucleotides to produce a 2'-3'- cyclic phosphate end product. |
From: PS51958 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | NendoU # | |||||||||
ACT_SITE | 31 | 31 | H | 1 | ||||||||
ACT_SITE | 46 | 46 | H | 1 | ||||||||
ACT_SITE | 86 | 86 | K | 1 |
Size range | 120-150 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | P0C6X9 (R1AB_CVMA5) |
Scope | Viruses; Nidovirales |
Comments | None |
Viruses | [44] |