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annotation rule: PRU01307 |
Accession | PRU01307 |
Dates | 2-MAR-2021 (Created) 2-MAR-2021 (Last updated, Version 1) |
Data class | Domain |
Predictors | PROSITE; PS51962; COV_NSP1 |
Name | Coronavirus (CoV) Nsp1 globular domain |
Function | Nsp1 is a characteristic feature of AlphaCoVs and BetaCoVs, which exhibits both functional conservation and mechanistic diversity in inhibiting host gene expression and antiviral responses. Although the sequence homologies among CoV Nsp1 proteins are low, the core structures share a relatively conserved domain. |
Similarity | Belongs to the coronaviruses polyprotein 1ab family. |
From: PS51962 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | CoV Nsp1 globular # |
Size range | 100-150 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | P0C6U5 (R1A_CVHN5) |
Scope | Viruses; Orthocoronavirinae |
Comments | None |
Viruses | [54] |