ProRule PRU01307

General rule information [?]

Accession PRU01307
Dates 2-MAR-2021 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS51962; COV_NSP1
Name Coronavirus (CoV) Nsp1 globular domain
Function Nsp1 is a characteristic feature of AlphaCoVs and BetaCoVs, which exhibits both functional conservation and mechanistic diversity in inhibiting host gene expression and antiviral responses. Although the sequence homologies among CoV Nsp1 proteins are low, the core structures share a relatively conserved domain.
Scope(s) Viruses
Example(s) P0C6U5 (R1A_CVHN5);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the coronaviruses polyprotein 1ab family.

Keywords [?]

Features [?]

From: PS51962
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="CoV Nsp1 globular #"

Additional information [?]

Size range 100-150 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]