General rule information
[?]
Accession |
PRU01356 |
Dates |
10-NOV-2022 (Created) 10-NOV-2022 (Last updated, Version 1) |
Function |
Common in Fungal Extracellular Membrane (CFEM) proteins, characterized by a distinctive pattern of eight cysteine residues of conserved interspacing, are widespread among fungi. The CFEM domain adopts a helical-basket fold that consists of six alpha-helices, and is uniquely stabilized by four disulfide bonds formed by its eight signature cysteines. |
Propagated annotation
[?]
GO:0005576; Cellular component: extracellular region.
case <FTTag:heme>
GO:0046872; Molecular function: metal ion binding.
end case
case <FTTag:disulf>
end case
From: PS52012 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DOMAIN
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from
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to
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CFEM #
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DISULFID
|
|
29
|
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69
|
|
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disulf
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C-x*-C
|
|
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DISULFID
|
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33
|
|
64
|
|
|
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disulf
|
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C-x*-C
|
|
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DISULFID
|
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43
|
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50
|
|
|
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disulf
|
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C-x*-C
|
|
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DISULFID
|
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52
|
|
85
|
|
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|
disulf
|
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C-x*-C
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|
BINDING
|
|
47
|
|
47
|
|
/ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue
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heme
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D
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Additional information
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Size range |
107-119 amino acids |
Related rules |
None |
Repeats |
1-4 |
Topology |
Undefined |
Example |
Q4WMA6 (CFMB_ASPFU) |
Scope |
Eukaryota; Ascomycota |
Comments |
None |
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distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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