annotation rule: PRU00362

General rule information [?]

Accession PRU00362
Dates 11-OCT-2004 (Created)
16-DEC-2016 (Last updated, Version 17)
Data class Domain
Predictors PROSITE; PS50990; PEPTIDASE_C39
Name Peptidase family C39 domain
Function This domain is a thiol peptidase found in ABC transporters, and belongs to the C39 peptidase family.

Propagated annotation [?]

Description [?]

case (<Feature:PS50990:7=C> and <Feature:PS50990:81=H>)
+ RecName: EC=3.4.22.-;
end case

Cross-references [?]

PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;
PS50990; PEPTIDASE_C39; 1;
PS50929; ABC_TM1F; 1;

Keywords [?]

case <OC:Bacteria> or <OC:Archaea>
end case

case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
end case

case <OC:Bacteria> or <OC:Archaea>
end case

case (<Feature:PS50990:7=C> and <Feature:PS50990:81=H>)
end case

Features [?]

From: PS00017
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     from     to       ATP #        
From: PS50990
DOMAIN     from     to       Peptidase C39 #        
case <Feature:PS50990:7=C>
ACT_SITE     7     7                
else case <Feature:PS50990:81=H>
ACT_SITE     81     81                
end case

Additional information [?]

Size range 121 amino acids
Related rules PRU01700
Repeats 1
Topology Undefined
Example P08716 (HLYBP_ECOLX)
Scope Bacteria
Comments A number of the proteins are classified as non-peptidase homologues as they either have been found experimentally to be without peptidase activity, or to lack amino acid residues that are believed to be essential for the catalytic activity.


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UniProtKB rule member sequences [?]