PROSITE documentation PDOC00202Neuraxin and MAP1B proteins repeated region signature
Description
MAP1B [1], and neuraxin [2] are neuronal microtubule-binding proteins. Both proteins contain a region that consists of 12 tandem repeats of a 17 residues motif.
The pattern we developed to detect this repeated region corresponds to the N-terminal ten residues of the repeated region.
Expert(s) to contact by email: Last update:December 2004 / Pattern and text revised.
-------------------------------------------------------------------------------
Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Noble M. Lewis S.A. Cowan N.J. |
| Title | The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau. | |
| Source | J. Cell Biol. 109:3367-3376(1989). | |
| PubMed ID | 2480963 |
| 2 | Authors | Rienitz A. Grenningloh G. Hermans-Borgmeyer I. Kirsch J. Littauer U.Z. Prior P. Gundelfinger E.D. Schmitt B. Betz H. |
| Title | Neuraxin, a novel putative structural protein of the rat central nervous system that is immunologically related to microtubule- associated protein 5. | |
| Source | EMBO J. 8:2879-2888(1989). | |
| PubMed ID | 2555150 |
Copyright
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
Miscellaneous
View entry in original PROSITE document format
View entry in raw text format (no links)