Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS. To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017. From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...] View this page in https
Cyclic AMP phosphodiesterase (EC 188.8.131.52) (cAMP-PDEase) catalyzes the
hydrolysis of cAMP to the corresponding nucleoside 5' monophosphate. While
most PDEases can be, on the basis of sequence similarities, grouped together
, there are at least two enzymes which do not belong to the main family of
PDEases and which represent a second class of these enzymes :
Slime mold Dictyostelium discoideum extracellular cAMP PDEase. This enzyme
plays an essential role in development by hydrolyzing the cAMP used as a
chemoattractant by aggregating cells.
Budding yeast and Candida albicans low-affinity cAMP PDEase (gene PDE1).
PROSITE is copyright. It is produced by the SIB Swiss Institute
Bioinformatics. There are no restrictions on its use by non-profit
institutions as long as its content is in no way modified. Usage by and
for commercial entities requires a license agreement. For information
about the licensing scheme send an email to
or see: prosite_license.html.