|PROSITE documentation PDOC00740
NAD-dependent glycerol-3-phosphate dehydrogenase signature
NAD-dependent glycerol-3-phosphate dehydrogenase (EC 188.8.131.52) (GPD) catalyzes
the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. It is a eukaryotic cytosolic homodimeric protein of about 40 Kd. As
a signature pattern we selected a glycine-rich region that is probably 
involved in NAD-binding.
April 2006 / Pattern revised.
PROSITE method (with tools and information) covered by this documentation:
|NAD_G3PDH, PS00957; NAD-dependent glycerol-3-phosphate dehydrogenase signature (PATTERN)
|Sequences in UniProtKB/Swiss-Prot known to belong to this class detected by PS00957:
||613 true positives with 26 false negatives.
|Other sequence(s) in UniProtKB/Swiss-Prot detected by PS00957:
|Matching PDB structures:
1EVY 1EVZ 1JDJ 1M66 ... [ALL]
||Otto J., Argos P., Rossmann M.G.
||Prediction of secondary structural elements in glycerol-3-phosphate dehydrogenase by comparison with other dehydrogenases.
||Eur. J. Biochem. 109:325-330(1980).
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