To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
PROSITE documentation PDOC00740

NAD-dependent glycerol-3-phosphate dehydrogenase signature





Description

NAD-dependent glycerol-3-phosphate dehydrogenase (EC 1.1.1.8) (GPD) catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. It is a eukaryotic cytosolic homodimeric protein of about 40 Kd. As a signature pattern we selected a glycine-rich region that is probably [1] involved in NAD-binding.

Last update:

April 2006 / Pattern revised.

Technical section

PROSITE method (with tools and information) covered by this documentation:

NAD_G3PDH, PS00957; NAD-dependent glycerol-3-phosphate dehydrogenase signature  (PATTERN)


Reference

1AuthorsOtto J., Argos P., Rossmann M.G.
TitlePrediction of secondary structural elements in glycerol-3-phosphate dehydrogenase by comparison with other dehydrogenases.
SourceEur. J. Biochem. 109:325-330(1980).
PubMed ID6773774



PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to
Prosite License or see: prosite_license.html.

Miscellaneous

View entry in original PROSITE document format
View entry in raw text format (no links)