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PROSITE documentation PDOC00915

Ribosomal protein S12e signature

Description:

A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Vertebrate S12 [1].
  • Trypanosoma brucei S12 [2].
  • Caenorhabditis elegans S12 (F54E7.2).
  • Drosophila S12.
  • Fungi S12.

These proteins have 130 to 150 amino acids. As a signature pattern, we selected a conserved region in the N-terminal part of these proteins.

Last update:

December 2001 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S12E, PS01189; Ribosomal protein S12e signature  (PATTERN)
Consensus pattern: [AS]-[LI]-[KREQP]-x(2)-[LIVM]-x(2)-[SA]-x(3)-[DNG]-G-[LIV]-x(2)-G-[LIV]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01189
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01189
• Scan Swiss-Prot/TrEMBL entries against PS01189
• view ligand binding statistics

References:

1 AuthorsLin A., Chan Y.-L., Jones R., Wool I.G.
TitleThe primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins.
SourceJ. Biol. Chem. 262:14343-14351(1987).
PubMed ID3308890
2 AuthorsMarchal C., Ismaili N., Pays E.
TitleA ribosomal S12-like gene of Trypanosoma brucei.
SourceMol. Biochem. Parasitol. 57:331-334(1993).
PubMed ID8433721

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