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PROSITE documentation PDOC00918

Ribosomal protein S8e signature

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities [1]. One of these families consists of:

  • Mammalian S8.
  • Caenorhabditis elegans S8 (F42C5.8).
  • Leishmania major S8.
  • Plant S8.
  • Yeast S8 (S14) (Rp19).
  • Archebacterial S8e.

These proteins have either about 220 amino acids (in eukaryotes) or about 125 amino acids (in archebacteria). As a signature pattern we selected a conserved stretch which is located in the N-terminal section and which is rich in positively charged residues.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S8E, PS01193; Ribosomal protein S8e signature  (PATTERN)
Consensus pattern: [KR]-x(2)-[ST]-G-[GAR]-x(5,6)-[KRHSA]-x-[KRT]-x-[KR]-x-[EA]-[LIMPA]-G
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01193
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01193
• Scan Swiss-Prot/TrEMBL entries against PS01193
• view ligand binding statistics
Matching PDB structures: 2KCO [ALL]

Reference:

1 AuthorsEngemann S., Herfurth E., Briesemeister U., Wittmann-Liebold B.
TitleAmino acid sequence of the ribosomal protein HS23 from the halophilic Haloarcula marismortui and homology studies to other ribosomal proteins.
SourceJ. Protein Chem. 14:189-195(1995).
PubMed ID7662106

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