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PROSITE documentation PDOC00931

Uncharacterized protein family UPF0001 signature

Description:

The following uncharacterized proteins have been shown [1] to share regions of similarities:

  • Yeast chromosome II hypothetical protein YBL036c.
  • Caenorhabditis elegans hypothetical protein F09E5.8.
  • Bacillus subtilis hypothetical protein ylmE.
  • Escherichia coli hypothetical protein yggS and HI0090, the corresponding Haemophilus influenzae protein.
  • Helicobacter pylori hypothetical protein HP0395.
  • Mycobacterium tuberculosis hypothetical protein MtCY270.20.
  • Synechocystis strain PCC 6803 hypothetical protein slr0556.
  • A Pseudomonas aeruginosa hypothetical protein in pilT 5'region.
  • A Vibrio alginolyticus hypothetical protein in pilT 5'region.

These are proteins of from 25 to 30 Kd which contain a number of conserved regions. As a signature pattern, we selected the best conserved region which is located in the first third of these proteins.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

UPF0001, PS01211; Uncharacterized protein family UPF0001 signature  (PATTERN)
Consensus pattern: [FW]-H-[FM]-[IV]-G-x-[LIV]-Q-x-[NKRQ]-[KN]-x(3)-[LIV]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01211
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01211
• Scan Swiss-Prot/TrEMBL entries against PS01211
• view ligand binding statistics
Matching PDB structures: 1B54 1CT5 1W8G [ALL]

Reference:

1 AuthorsBairoch A., Rudd K.E.
SourceUnpublished observations (1996).

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