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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC00934
Uncharacterized protein family UPF0016 signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00934

Description

The following uncharacterized proteins have been shown [1] to share regions of similarities:

  • Yeast hypothetical protein YBR187w.
  • Fission yeast hypothetical protein SpAC17G8.08c.
  • Mouse protein pFT27.
  • Synechocystis strain PCC 6803 hypothetical protein sll0615.

These are hydrophobic proteins of 200 to 320 amino acids that seem to contain six or seven transmembrane domains. As a signature pattern, we selected a conserved region which seems, in the eukaryotic proteins of this family, to directly follow the second transmembrane domain.

Last update:

November 1997 / First entry.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

UPF0016, PS01214; Uncharacterized protein family UPF0016 signature  (PATTERN)


Reference

1AuthorsBairoch A.
SourceUnpublished observations (1996).



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