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PROSITE documentation PDOC00943

Uncharacterized protein family UPF0012 signature

Description:

The following uncharacterized proteins have been shown [1] to share regions of similarities:

  • Yeast chromosome X hypothetical protein YJL126w.
  • Yeast chromosome XII hypothetical protein YLR351c.
  • Fission yeast hypothetical protein SpAC26A3.11.
  • Escherichia coli hypothetical protein ybeM.
  • Bacillus subtilis hypothetical protein yhcX.
  • Mycobacterium tuberculosis hypothetical protein MtCY20G9.06c.
  • Synechocystis strain PCC 6803 hypothetical protein sll0601.
  • A Pseudomonas fluorescens hypothetical protein in pqqF 5'region.
  • A Staphylococcus hypothetical protein in agr operon.

Except for yhcX which is larger, these are protein of about 30 to 35 Kd which contain, in their central section, a well conserved region centered on a cysteine residue.

Last update:

December 2004 / Pattern and text revised.

Technical section:

PROSITE method (with tools and information) covered by this documentation:

UPF0012, PS01227; Uncharacterized protein family UPF0012 signature  (PATTERN)
Consensus pattern: [GTAL]-x(2)-[IVT]-C-Y-D-[LIVM]-x-F-P-x(9)-[GD]
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
• Retrieve the sequence logo from the alignment
• Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS01227
• Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS01227
• Scan Swiss-Prot/TrEMBL entries against PS01227
• view ligand binding statistics
Matching PDB structures: 1EMS 1F89 [ALL]

Reference:

1 AuthorsBairoch A.
SourceUnpublished observations (1995).

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