Entry: PS00094

General information about the entry
Entry name C5_MTASE_1
Accession number PS00094
Entry type PATTERN
Date APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00089
Associated ProRule PRU10018
Name and characterization of the entry
DescriptionC-5 cytosine-specific DNA methylases active site.
Pattern [DENKS]-x-[FLIV]-x(2)-[GSTC]-x-P-C-x-{V}-[FYWLIM]-S.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 88 hits in 88 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 77 hits in 77 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 11 hits in 11 different sequences
  • Number of known missed hits: 15
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 87.50 %
  • Recall (true hits / (true hits + false negatives)): 83.70 %
Comments
  • Taxonomic range: Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 8,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CMT1_MAIZE  (Q9AXT8), CMT2_MAIZE  (Q9ARI6), CMT3_ARATH  (Q94F88), 
CMT3_MAIZE  (Q8LPU5), DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), 
DNM1A_ORYSJ (Q7Y1I7), DNM1B_ORYSJ (B1Q3J6), DNM3A_CHICK (Q4W5Z4), 
DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), DNM3A_RAT   (Q1LZ53), 
DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), DNMT1_ARATH (P34881), 
DNMT1_BOVIN (Q24K09), DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), 
DNMT1_MOUSE (P13864), DNMT1_PARLI (Q27746), DNMT1_RAT   (Q9Z330), 
DNMT_FRG3G  (Q67472), MTA1_CELCE  (P31974), MTA1_RUEGE  (P94147), 
MTAA_SYNP2  (P34882), MTB1_BREBE  (P34905), MTB1_BREEP  (P10283), 
MTB1_HERAU  (P25262), MTB1_LYSSH  (P13906), MTB1_NEIGO  (Q59603), 
MTB5_NEIGO  (Q59605), MTB6_BACSF  (P43420), MTBA_BACAR  (P19888), 
MTBB_BPSPB  (P09389), MTBF_BACIU  (P17044), MTBP_BACSU  (P68585), 
MTBP_BPPHT  (P68586), MTBR_BACIU  (P06530), MTBR_BPRH1  (P09915), 
MTBS_BPSPR  (P00476), MTC1_HERAU  (P25263), MTC1_PBCVI  (P36216), 
MTC2_HERAU  (P25264), MTD1_DESNO  (P05302), MTD1_HERAU  (P24600), 
MTD2_HERAU  (P25265), MTD5_DACSA  (P50185), MTE1_HERAU  (P25266), 
MTE2_ECOLX  (P05101), MTE8_ECOLX  (P50196), MTF1_FUSNU  (P34906), 
MTF7_NEIGO  (Q59606), MTG1_HAEGA  (P25282), MTG1_HERAU  (P25267), 
MTG2_HAEGA  (P25283), MTH1_HAEPH  (P05102), MTH2_HAEAE  (O30868), 
MTH2_HAEPA  (P15446), MTH3_HAEAE  (P20589), MTH5_HAEIN  (P45000), 
MTHA_HAEPH  (P50192), MTM1_MORSP  (P11408), MTM4_NEIGO  (P31033), 
MTN1_NOCAE  (P50188), MTN4_NEILA  (P50182), MTNX_NEILA  (P24581), 
MTP1_PSYTA  (O33481), MTP2_NEIGO  (P08455), MTS1_SALIN  (P09795), 
MTS2_SHISO  (P34879), MTS3_STAAU  (P16668), MTS9_STAAU  (P23737), 
MTSA_LACLC  (P34877), MTSB_LACLC  (P34878), MTSI_SPISQ  (P15840), 
MTX2_XANOR  (P52311), YDIP_BACSU  (O34680)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
DRM1_ARATH  (Q9LXE5), DRM2_ARATH  (Q9M548), MT36_OCEIH  (Q8EL95), 
MT51_METJA  (Q57983), MT52_METJA  (Q58600), MTA1_ACEPA  (O52702), 
MTD1_NEIMC  (Q9RLM4), MTHT_METTF  (P29567), MTS1_STRAH  (O31073), 
PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), TRDMT_HUMAN (O14717), 
TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), YDIO_BACSU  (O34939)
False positive hits (sequences which do not belong to the set under consideration):
DPH1_ENCCU  (Q8SUZ5), GATA_NEOSM  (Q2GEE7), MEND_PHOLL  (Q7N2K3), 
RTPR_LACAC  (Q5FMX8), RTPR_LACBA  (Q03PB4), RTPR_LACH4  (A8YW74), 
SYA_METBU   (Q12U25), WISP2_HUMAN (O76076), Y94X_SYNY3  (P77971), 
YME21_CANAL (Q5A089), YME22_CANAL (Q5A061)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 10MH; 1DCT; 1FJX; 1HMY; 1M0E; 1MHT; 1SKM; 2C7O; 2C7P; 2C7Q; 2C7R; 2HMY; 2HR1; 2I9K; 2QRV; 2UYC; 2UYH; 2UZ4; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 4DA4; 4FT4; 4MHT; 5MHT; 6MHT; 7MHT; 8MHT; 9MHT;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission

If you would like to retrieve all the Swiss-Prot entries referenced in the DR lines of this entry (with the exception of false positive hits) , you can enter a file name. These entries will then be saved to a file under this name. (Please note that this temporary file will only be kept for 1 week.)

File name:

Format: Swiss-Prot Fasta

or