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Entry: PS00094

General information about the entry

Entry name [info] C5_MTASE_1
Accession [info] PS00094
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 20-DEC-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00089
Associated ProRule [info] PRU10018

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases active site.
Pattern [info]
[DENKS]-x-[FLIV]-x(2)-[GSTC]-x-P-C-x-{V}-[FYWLIM]-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_12 which contains 556'388 sequence entries.


Total number of hits 95 in 95 different sequences
Number of true positive hits 86 in 86 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 90.53 %
Recall (true positives / (true positives + false negatives)) 85.15 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
86 sequences

CMT1_MAIZE  (Q9AXT8    ), CMT1_ORYSJ  (A0A0P0VUY4), CMT2_MAIZE  (Q9ARI6    ), 
CMT2_ORYSJ  (Q5KQL9    ), CMT3_ARATH  (Q94F88    ), CMT3_MAIZE  (Q8LPU5    ), 
CMT3_ORYSJ  (C0SQ89    ), DCM_ECO57   (P0AEE0    ), DCM_ECOLI   (P0AED9    ), 
DMT_BPP1    (Q71TL0    ), DNM1A_ORYSJ (Q7Y1I7    ), DNM1B_ORYSJ (B1Q3J6    ), 
DNM3A_CHICK (Q4W5Z4    ), DNM3A_HUMAN (Q9Y6K1    ), DNM3A_MOUSE (O88508    ), 
DNM3A_RAT   (Q1LZ53    ), DNM3B_HUMAN (Q9UBC3    ), DNM3B_MOUSE (O88509    ), 
DNM3C_MOUSE (P0DOY1    ), DNMT1_ARATH (P34881    ), DNMT1_BOVIN (Q24K09    ), 
DNMT1_CHICK (Q92072    ), DNMT1_HUMAN (P26358    ), DNMT1_MOUSE (P13864    ), 
DNMT1_PARLI (Q27746    ), DNMT1_RAT   (Q9Z330    ), DNMT2_ARATH (Q9M0S8    ), 
DNMT3_ARATH (Q9T0I1    ), DNMT4_ARATH (O23273    ), DNMT_FRG3G  (Q67472    ), 
MTA1_CELCE  (P31974    ), MTA1_THAGE  (P94147    ), MTAA_SYNP2  (P34882    ), 
MTAP_ARTPN  (D4ZX35    ), MTB1_BREBE  (P34905    ), MTB1_BREEP  (P10283    ), 
MTB1_HERAU  (P25262    ), MTB1_LYSSH  (P13906    ), MTB1_NEIGO  (Q59603    ), 
MTB5_NEIGO  (Q59605    ), MTB6_BACSF  (P43420    ), MTBA_ANEAE  (P19888    ), 
MTBB_BPSPB  (P09389    ), MTBF_BACIU  (P17044    ), MTBP_BACSU  (P68585    ), 
MTBP_BPPHT  (P68586    ), MTBR_BACIU  (P06530    ), MTBR_BPRH1  (P09915    ), 
MTBS_BPSPR  (P00476    ), MTC1_HERAU  (P25263    ), MTC1_PBCVI  (P36216    ), 
MTC2_HERAU  (P25264    ), MTD1_DESNO  (P05302    ), MTD1_HERAU  (P24600    ), 
MTD2_HERAU  (P25265    ), MTD5_DACSA  (P50185    ), MTE1_HERAU  (P25266    ), 
MTE2_ECOLX  (P05101    ), MTE8_ECOLX  (P50196    ), MTF1_FUSNU  (P34906    ), 
MTF7_NEIGO  (Q59606    ), MTG1_AVIPA  (P25282    ), MTG1_HERAU  (P25267    ), 
MTG2_AVIPA  (P25283    ), MTH1_HAEPH  (P05102    ), MTH2_HAEAE  (O30868    ), 
MTH2_HAEPA  (P15446    ), MTH3_HAEAE  (P20589    ), MTH5_HAEIN  (P45000    ), 
MTHA_HAEPH  (P50192    ), MTM1_MORSP  (P11408    ), MTM4_NEIGO  (P31033    ), 
MTN1_NOCAE  (P50188    ), MTN4_NEILA  (P50182    ), MTNX_NEILA  (P24581    ), 
MTP1_PSYTA  (O33481    ), MTP2_NEIGO  (P08455    ), MTS1_SALIN  (P09795    ), 
MTS2_SHISO  (P34879    ), MTS3_STAAU  (P16668    ), MTS9_STAAU  (P23737    ), 
MTSA_LACLC  (P34877    ), MTSB_LACLC  (P34878    ), MTSI_SPISQ  (P15840    ), 
MTX2_XANOR  (P52311    ), YDIP_BACSU  (O34680    )
» more

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

DRM1L_ARATH (Q9LXE5    ), DRM2_ARATH  (Q9M548    ), MT36_OCEIH  (Q8EL95    ), 
MT51_METJA  (Q57983    ), MT52_METJA  (Q58600    ), MTA1_ACEPA  (O52702    ), 
MTD1_NEIMC  (Q9RLM4    ), MTHT_METTF  (P29567    ), MTS1_STRAH  (O31073    ), 
PMT1M_SCHPO (P40999    ), TRDMT_BOVIN (Q7YS61    ), TRDMT_HUMAN (O14717    ), 
TRDMT_MOUSE (O55055    ), TRDMT_RAT   (Q4G073    ), YDIO_BACSU  (O34939    )
» more

UniProtKB/Swiss-Prot
False positive sequences
9 sequences

GATA_NEOSM  (Q2GEE7    ), MEND_PHOLL  (Q7N2K3    ), RTPR_LACAC  (Q5FMX8    ), 
RTPR_LACBA  (Q03PB4    ), RTPR_LACH4  (A8YW74    ), SYA_METBU   (Q12U25    ), 
WISP2_HUMAN (O76076    ), Y94X_SYNY3  (P77971    ), YME2_CANAL  (Q5A061    )
» more

PDB
[Detailed view]
47 PDB

10MH; 1DCT; 1FJX; 1HMY; 1M0E; 1MHT; 1SKM; 2C7O; 2C7P; 2C7Q; 2C7R; 2HMY; 2HR1; 2I9K; 2QRV; 2UYC; 2UYH; 2UZ4; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 4DA4; 4FT4; 4MHT; 4U7P; 4U7T; 4WXX; 4YOC; 5CIY; 5GUT; 5GUV; 5LOD; 5MHT; 5WY1; 6MHT; 7MHT; 8MHT; 9MHT
» more

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