Entry: PS00094

General information about the entry

Entry name [info] C5_MTASE_1
Accession [info] PS00094
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00089
Associated ProRule [info] PRU10018

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases active site.
Pattern [info]
[DENKS]-x-[FLIV]-x(2)-[GSTC]-x-P-C-x-{V}-[FYWLIM]-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 92 in 92 different sequences
Number of true positive hits 82 in 82 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 89.13 %
Recall (true positives / (true positives + false negatives)) 84.54 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
82 sequences

CMT1_MAIZE  (Q9AXT8), CMT2_MAIZE  (Q9ARI6), CMT3_ARATH  (Q94F88), 
CMT3_MAIZE  (Q8LPU5), DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), 
DMT_BPP1    (Q71TL0), DNM1A_ORYSJ (Q7Y1I7), DNM1B_ORYSJ (B1Q3J6), 
DNM3A_CHICK (Q4W5Z4), DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), 
DNM3A_RAT   (Q1LZ53), DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), 
DNMT1_ARATH (P34881), DNMT1_BOVIN (Q24K09), DNMT1_CHICK (Q92072), 
DNMT1_HUMAN (P26358), DNMT1_MOUSE (P13864), DNMT1_PARLI (Q27746), 
DNMT1_RAT   (Q9Z330), DNMT2_ARATH (Q9M0S8), DNMT3_ARATH (Q9T0I1), 
DNMT4_ARATH (O23273), DNMT_FRG3G  (Q67472), MTA1_CELCE  (P31974), 
MTA1_THAGE  (P94147), MTAA_SYNP2  (P34882), MTAP_ARTPN  (D4ZX35), 
MTB1_BREBE  (P34905), MTB1_BREEP  (P10283), MTB1_HERAU  (P25262), 
MTB1_LYSSH  (P13906), MTB1_NEIGO  (Q59603), MTB5_NEIGO  (Q59605), 
MTB6_BACSF  (P43420), MTBA_ANEAE  (P19888), MTBB_BPSPB  (P09389), 
MTBF_BACIU  (P17044), MTBP_BACSU  (P68585), MTBP_BPPHT  (P68586), 
MTBR_BACIU  (P06530), MTBR_BPRH1  (P09915), MTBS_BPSPR  (P00476), 
MTC1_HERAU  (P25263), MTC1_PBCVI  (P36216), MTC2_HERAU  (P25264), 
MTD1_DESNO  (P05302), MTD1_HERAU  (P24600), MTD2_HERAU  (P25265), 
MTD5_DACSA  (P50185), MTE1_HERAU  (P25266), MTE2_ECOLX  (P05101), 
MTE8_ECOLX  (P50196), MTF1_FUSNU  (P34906), MTF7_NEIGO  (Q59606), 
MTG1_AVIPA  (P25282), MTG1_HERAU  (P25267), MTG2_AVIPA  (P25283), 
MTH1_HAEPH  (P05102), MTH2_HAEAE  (O30868), MTH2_HAEPA  (P15446), 
MTH3_HAEAE  (P20589), MTH5_HAEIN  (P45000), MTHA_HAEPH  (P50192), 
MTM1_MORSP  (P11408), MTM4_NEIGO  (P31033), MTN1_NOCAE  (P50188), 
MTN4_NEILA  (P50182), MTNX_NEILA  (P24581), MTP1_PSYTA  (O33481), 
MTP2_NEIGO  (P08455), MTS1_SALIN  (P09795), MTS2_SHISO  (P34879), 
MTS3_STAAU  (P16668), MTS9_STAAU  (P23737), MTSA_LACLC  (P34877), 
MTSB_LACLC  (P34878), MTSI_SPISQ  (P15840), MTX2_XANOR  (P52311), 
YDIP_BACSU  (O34680)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

DRM1_ARATH  (Q9LXE5), DRM2_ARATH  (Q9M548), MT36_OCEIH  (Q8EL95), 
MT51_METJA  (Q57983), MT52_METJA  (Q58600), MTA1_ACEPA  (O52702), 
MTD1_NEIMC  (Q9RLM4), MTHT_METTF  (P29567), MTS1_STRAH  (O31073), 
PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), TRDMT_HUMAN (O14717), 
TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), YDIO_BACSU  (O34939)
» More

UniProtKB/Swiss-Prot
False positive sequences
10 sequences

GATA_NEOSM  (Q2GEE7), MEND_PHOLL  (Q7N2K3), RTPR_LACAC  (Q5FMX8), 
RTPR_LACBA  (Q03PB4), RTPR_LACH4  (A8YW74), SYA_METBU   (Q12U25), 
WISP2_HUMAN (O76076), Y94X_SYNY3  (P77971), YME21_CANAL (Q5A089), 
YME22_CANAL (Q5A061)
» More

PDB
[Detailed view]
40 PDB

10MH; 1DCT; 1FJX; 1HMY; 1M0E; 1MHT; 1SKM; 2C7O; 2C7P; 2C7Q; 2C7R; 2HMY; 2HR1; 2I9K; 2QRV; 2UYC; 2UYH; 2UZ4; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 4DA4; 4FT4; 4MHT; 4U7P; 4U7T; 5MHT; 6MHT; 7MHT; 8MHT; 9MHT
» More

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