Entry: PS00094

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General information about the entry

Entry name [info] C5_MTASE_1
Accession [info] PS00094
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00089
Associated ProRule [info] PRU10018

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases active site.
Pattern [info]
[DENKS]-x-[FLIV]-x(2)-[GSTC]-x-P-C-x-{V}-[FYWLIM]-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 91 in 91 different sequences
Number of true positive hits 81 in 81 different sequences
Number of 'unknown' hits
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 15
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 89.01 %
Recall (true positives / (true positives + false negatives)) 84.38 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
81 sequences

CMT1_MAIZE  (Q9AXT8), CMT2_MAIZE  (Q9ARI6), CMT3_ARATH  (Q94F88), 
CMT3_MAIZE  (Q8LPU5), DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), 
DNM1A_ORYSJ (Q7Y1I7), DNM1B_ORYSJ (B1Q3J6), DNM3A_CHICK (Q4W5Z4), 
DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), DNM3A_RAT   (Q1LZ53), 
DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), DNMT1_ARATH (P34881), 
DNMT1_BOVIN (Q24K09), DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), 
DNMT1_MOUSE (P13864), DNMT1_PARLI (Q27746), DNMT1_RAT   (Q9Z330), 
DNMT2_ARATH (Q9M0S8), DNMT3_ARATH (Q9T0I1), DNMT4_ARATH (O23273), 
DNMT_FRG3G  (Q67472), MTA1_CELCE  (P31974), MTA1_THAGE  (P94147), 
MTAA_SYNP2  (P34882), MTAP_ARTPN  (D4ZX35), MTB1_BREBE  (P34905), 
MTB1_BREEP  (P10283), MTB1_HERAU  (P25262), MTB1_LYSSH  (P13906), 
MTB1_NEIGO  (Q59603), MTB5_NEIGO  (Q59605), MTB6_BACSF  (P43420), 
MTBA_ANEAE  (P19888), MTBB_BPSPB  (P09389), MTBF_BACIU  (P17044), 
MTBP_BACSU  (P68585), MTBP_BPPHT  (P68586), MTBR_BACIU  (P06530), 
MTBR_BPRH1  (P09915), MTBS_BPSPR  (P00476), MTC1_HERAU  (P25263), 
MTC1_PBCVI  (P36216), MTC2_HERAU  (P25264), MTD1_DESNO  (P05302), 
MTD1_HERAU  (P24600), MTD2_HERAU  (P25265), MTD5_DACSA  (P50185), 
MTE1_HERAU  (P25266), MTE2_ECOLX  (P05101), MTE8_ECOLX  (P50196), 
MTF1_FUSNU  (P34906), MTF7_NEIGO  (Q59606), MTG1_AVIPA  (P25282), 
MTG1_HERAU  (P25267), MTG2_AVIPA  (P25283), MTH1_HAEPH  (P05102), 
MTH2_HAEAE  (O30868), MTH2_HAEPA  (P15446), MTH3_HAEAE  (P20589), 
MTH5_HAEIN  (P45000), MTHA_HAEPH  (P50192), MTM1_MORSP  (P11408), 
MTM4_NEIGO  (P31033), MTN1_NOCAE  (P50188), MTN4_NEILA  (P50182), 
MTNX_NEILA  (P24581), MTP1_PSYTA  (O33481), MTP2_NEIGO  (P08455), 
MTS1_SALIN  (P09795), MTS2_SHISO  (P34879), MTS3_STAAU  (P16668), 
MTS9_STAAU  (P23737), MTSA_LACLC  (P34877), MTSB_LACLC  (P34878), 
MTSI_SPISQ  (P15840), MTX2_XANOR  (P52311), YDIP_BACSU  (O34680)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

DRM1_ARATH  (Q9LXE5), DRM2_ARATH  (Q9M548), MT36_OCEIH  (Q8EL95), 
MT51_METJA  (Q57983), MT52_METJA  (Q58600), MTA1_ACEPA  (O52702), 
MTD1_NEIMC  (Q9RLM4), MTHT_METTF  (P29567), MTS1_STRAH  (O31073), 
PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), TRDMT_HUMAN (O14717), 
TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), YDIO_BACSU  (O34939)
» More

UniProtKB/Swiss-Prot
False positive sequences
10 sequences

GATA_NEOSM  (Q2GEE7), MEND_PHOLL  (Q7N2K3), RTPR_LACAC  (Q5FMX8), 
RTPR_LACBA  (Q03PB4), RTPR_LACH4  (A8YW74), SYA_METBU   (Q12U25), 
WISP2_HUMAN (O76076), Y94X_SYNY3  (P77971), YME21_CANAL (Q5A089), 
YME22_CANAL (Q5A061)
» More


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