Entry: PS00095

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General information about the entry

Entry name [info] C5_MTASE_2
Accession [info] PS00095
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2003 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00089

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases C-terminal signature.
Pattern [info]
[RKQGTF]-x(2)-G-N-[SA]-[LIVF]-x-[VIP]-x-[LVMT]-x(3)-[LIVM]-x(3)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 71 in 71 different sequences
Number of true positive hits 61 in 61 different sequences
Number of 'unknown' hits
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 23
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 85.92 %
Recall (true positives / (true positives + false negatives)) 72.62 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
61 sequences

DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), DNM1A_ORYSJ (Q7Y1I7), 
DNM1B_ORYSJ (B1Q3J6), DNMT1_ARATH (P34881), DNMT1_BOVIN (Q24K09), 
DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), DNMT1_MOUSE (P13864), 
DNMT1_PARLI (Q27746), DNMT1_RAT   (Q9Z330), MT36_OCEIH  (Q8EL95), 
MTA1_THAGE  (P94147), MTAB_SYNP2  (P34883), MTB1_BREEP  (P10283), 
MTB1_HERAU  (P25262), MTB1_LYSSH  (P13906), MTB6_BACSF  (P43420), 
MTBA_ANEAE  (P19888), MTBF_BACIU  (P17044), MTBP_BACSU  (P68585), 
MTBP_BPPHT  (P68586), MTBR_BACIU  (P06530), MTBR_BPRH1  (P09915), 
MTBS_BPSPR  (P00476), MTC1_HERAU  (P25263), MTC2_HERAU  (P25264), 
MTD1_DESNO  (P05302), MTD1_HERAU  (P24600), MTD2_HERAU  (P25265), 
MTD5_DACSA  (P50185), MTE1_HERAU  (P25266), MTE2_ECOLX  (P05101), 
MTE8_ECOLX  (P50196), MTF1_FUSNU  (P34906), MTH1_HAEPH  (P05102), 
MTH2_HAEAE  (O30868), MTH3_HAEAE  (P20589), MTH5_HAEIN  (P45000), 
MTHA_HAEPH  (P50192), MTHT_METTF  (P29567), MTM1_MORSP  (P11408), 
MTM4_NEIGO  (P31033), MTN1_NOCAE  (P50188), MTNX_NEILA  (P24581), 
MTP1_PSYTA  (O33481), MTP2_NEIGO  (P08455), MTS1_SALIN  (P09795), 
MTS2_SHISO  (P34879), MTS3_STAAU  (P16668), MTS9_STAAU  (P23737), 
MTSA_LACLC  (P34877), MTSB_LACLC  (P34878), MTSI_SPISQ  (P15840), 
MTX2_XANOR  (P52311), PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), 
TRDMT_HUMAN (O14717), TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), 
YDIP_BACSU  (O34680)
» More

UniProtKB/Swiss-Prot
False negative sequences
23 sequences

DNM3A_CHICK (Q4W5Z4), DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), 
DNM3A_RAT   (Q1LZ53), DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), 
DRM1_ARATH  (Q9LXE5), DRM2_ARATH  (Q9M548), MT51_METJA  (Q57983), 
MT52_METJA  (Q58600), MTA1_CELCE  (P31974), MTAP_ARTPN  (D4ZX35), 
MTB1_BREBE  (P34905), MTB1_NEIGO  (Q59603), MTB5_NEIGO  (Q59605), 
MTC1_PBCVI  (P36216), MTD1_NEIMC  (Q9RLM4), MTF7_NEIGO  (Q59606), 
MTG1_AVIPA  (P25282), MTG2_AVIPA  (P25283), MTH2_HAEPA  (P15446), 
MTN4_NEILA  (P50182), YDIO_BACSU  (O34939)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

MTBB_BPSPB  (P09389), MTG1_HERAU  (P25267)

		
UniProtKB/Swiss-Prot
False positive sequences
10 sequences

ATPB_MYCGI  (A4T8K2), ATPB_MYCLE  (P45823), GCY8E_DROME (Q8INF0), 
OBG_BORAP   (Q0SM73), OBG_BORBU   (O51722), OBG_BORBZ   (B7J0M7), 
OBG_BORGA   (Q65ZZ3), WCAF_ECOLI  (P0ACD2), WCAF_SHIFL  (P0ACD3), 
YBBP_BACSU  (Q45589)
» More

PDB
[Detailed view]
40 PDB

10MH; 1DCT; 1FJX; 1G55; 1HMY; 1M0E; 1MHT; 1SKM; 1SVU; 2C7O; 2C7P; 2C7Q; 2C7R; 2HMY; 2HR1; 2I9K; 2UYC; 2UYH; 2UZ4; 2Z6A; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 3UBT; 4DA4; 4MHT; 5MHT; 6MHT; 7MHT; 8MHT; 9MHT
» More

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