Entry: PS00095

General information about the entry

Entry name [info] C5_MTASE_2
Accession [info] PS00095
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2003 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00089

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases C-terminal signature.
Pattern [info]
[RKQGTF]-x(2)-G-N-[SA]-[LIVF]-x-[VIP]-x-[LVMT]-x(3)-[LIVM]-x(3)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 74 in 74 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 23
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 86.49 %
Recall (true positives / (true positives + false negatives)) 73.56 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), DNM1A_ORYSJ (Q7Y1I7), 
DNM1B_ORYSJ (B1Q3J6), DNMT1_ARATH (P34881), DNMT1_BOVIN (Q24K09), 
DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), DNMT1_MOUSE (P13864), 
DNMT1_PARLI (Q27746), DNMT1_RAT   (Q9Z330), DNMT2_ARATH (Q9M0S8), 
DNMT3_ARATH (Q9T0I1), DNMT4_ARATH (O23273), MT36_OCEIH  (Q8EL95), 
MTA1_THAGE  (P94147), MTAB_SYNP2  (P34883), MTB1_BREEP  (P10283), 
MTB1_HERAU  (P25262), MTB1_LYSSH  (P13906), MTB6_BACSF  (P43420), 
MTBA_ANEAE  (P19888), MTBF_BACIU  (P17044), MTBP_BACSU  (P68585), 
MTBP_BPPHT  (P68586), MTBR_BACIU  (P06530), MTBR_BPRH1  (P09915), 
MTBS_BPSPR  (P00476), MTC1_HERAU  (P25263), MTC2_HERAU  (P25264), 
MTD1_DESNO  (P05302), MTD1_HERAU  (P24600), MTD2_HERAU  (P25265), 
MTD5_DACSA  (P50185), MTE1_HERAU  (P25266), MTE2_ECOLX  (P05101), 
MTE8_ECOLX  (P50196), MTF1_FUSNU  (P34906), MTH1_HAEPH  (P05102), 
MTH2_HAEAE  (O30868), MTH3_HAEAE  (P20589), MTH5_HAEIN  (P45000), 
MTHA_HAEPH  (P50192), MTHT_METTF  (P29567), MTM1_MORSP  (P11408), 
MTM4_NEIGO  (P31033), MTN1_NOCAE  (P50188), MTNX_NEILA  (P24581), 
MTP1_PSYTA  (O33481), MTP2_NEIGO  (P08455), MTS1_SALIN  (P09795), 
MTS2_SHISO  (P34879), MTS3_STAAU  (P16668), MTS9_STAAU  (P23737), 
MTSA_LACLC  (P34877), MTSB_LACLC  (P34878), MTSI_SPISQ  (P15840), 
MTX2_XANOR  (P52311), PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), 
TRDMT_HUMAN (O14717), TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), 
YDIP_BACSU  (O34680)
» More

UniProtKB/Swiss-Prot
False negative sequences
23 sequences

DNM3A_CHICK (Q4W5Z4), DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), 
DNM3A_RAT   (Q1LZ53), DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), 
DRM1_ARATH  (Q9LXE5), DRM2_ARATH  (Q9M548), MT51_METJA  (Q57983), 
MT52_METJA  (Q58600), MTA1_CELCE  (P31974), MTAP_ARTPN  (D4ZX35), 
MTB1_BREBE  (P34905), MTB1_NEIGO  (Q59603), MTB5_NEIGO  (Q59605), 
MTC1_PBCVI  (P36216), MTD1_NEIMC  (Q9RLM4), MTF7_NEIGO  (Q59606), 
MTG1_AVIPA  (P25282), MTG2_AVIPA  (P25283), MTH2_HAEPA  (P15446), 
MTN4_NEILA  (P50182), YDIO_BACSU  (O34939)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

MTBB_BPSPB  (P09389), MTG1_HERAU  (P25267)

		
UniProtKB/Swiss-Prot
False positive sequences
10 sequences

ATPB_MYCGI  (A4T8K2), ATPB_MYCLE  (P45823), GCY8E_DROME (Q8INF0), 
OBG_BORAP   (Q0SM73), OBG_BORBU   (O51722), OBG_BORBZ   (B7J0M7), 
OBG_BORGA   (Q65ZZ3), WCAF_ECOLI  (P0ACD2), WCAF_SHIFL  (P0ACD3), 
YBBP_BACSU  (Q45589)
» More

PDB
[Detailed view]
40 PDB

10MH; 1DCT; 1FJX; 1G55; 1HMY; 1M0E; 1MHT; 1SKM; 1SVU; 2C7O; 2C7P; 2C7Q; 2C7R; 2HMY; 2HR1; 2I9K; 2UYC; 2UYH; 2UZ4; 2Z6A; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 3UBT; 4DA4; 4MHT; 5MHT; 6MHT; 7MHT; 8MHT; 9MHT
» More

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