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Entry: PS00126
General information about the entry
Entry namePDEASE_I
Accession numberPS00126
Entry typePATTERN
DateAPR-1990 (CREATED); JUL-1998 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00116
Name and characterization of the entry
Description3'5'-cyclic nucleotide phosphodiesterases signature.
PatternH-D-[LIVMFY]-x-H-x-[AG]-x(2)-[NQ]-x-[LIVMFY].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 96 hits in 96 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 95 hits in 95 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 1 hits in 1 different sequences
  • Number of known missed hits: 0
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 98.96 %
  • Recall (true hits / (true hits + false negatives)): 100.00 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
PDE10_HUMAN (Q9Y233), PDE10_MOUSE (Q8CA95), PDE10_RAT   (Q9QYJ6), 
PDE11_DROME (Q9VJ79), PDE11_HUMAN (Q9HCR9), PDE11_MOUSE (P0C1Q2), 
PDE11_RAT   (Q8VID6), PDE11_TAKRU (Q1KKS3), PDE1A_BOVIN (P14100), 
PDE1A_HUMAN (P54750), PDE1A_MOUSE (Q61481), PDE1B_BOVIN (Q01061), 
PDE1B_CRIGR (Q64395), PDE1B_HUMAN (Q01064), PDE1B_MOUSE (Q01065), 
PDE1B_RAT   (Q01066), PDE1C_HUMAN (Q14123), PDE1C_MOUSE (Q64338), 
PDE1C_RAT   (Q63421), PDE1_CAEEL  (O18696), PDE2A_BOVIN (P14099), 
PDE2A_HUMAN (O00408), PDE2A_MOUSE (Q922S4), PDE2A_RAT   (Q01062), 
PDE2_CAEEL  (P30645), PDE2_DICDI  (Q23917), PDE2_YEAST  (P06776), 
PDE3A_HUMAN (Q14432), PDE3A_MOUSE (Q9Z0X4), PDE3A_RAT   (Q62865), 
PDE3B_HUMAN (Q13370), PDE3B_MOUSE (Q61409), PDE3B_RAT   (Q63085), 
PDE3_CAEEL  (Q8I0P7), PDE3_DICDI  (B0G0Y8), PDE4A_DROME (Q9W4T4), 
PDE4A_HUMAN (P27815), PDE4A_MOUSE (O89084), PDE4A_RAT   (P54748), 
PDE4B_DROME (P12252), PDE4B_HUMAN (Q07343), PDE4B_RAT   (P14646), 
PDE4C_DROME (Q9W4S9), PDE4C_HUMAN (Q08493), PDE4C_MOUSE (Q3UEI1), 
PDE4C_RAT   (P14644), PDE4D_DROME (Q9W4T0), PDE4D_HUMAN (Q08499), 
PDE4D_MOUSE (Q01063), PDE4D_RAT   (P14270), PDE4E_DROME (Q8IRU4), 
PDE4_CAEEL  (Q22000), PDE4_DICDI  (Q86H13), PDE5A_BOVIN (Q28156), 
PDE5A_CANFA (O77746), PDE5A_HUMAN (O76074), PDE5A_MOUSE (Q8CG03), 
PDE5A_RAT   (O54735), PDE5_CAEEL  (P91119), PDE6A_BOVIN (P11541), 
PDE6A_CANFA (Q28263), PDE6A_HUMAN (P16499), PDE6A_MOUSE (P27664), 
PDE6B_BOVIN (P23439), PDE6B_CANFA (P33726), PDE6B_HUMAN (P35913), 
PDE6B_MOUSE (P23440), PDE6C_BOVIN (P16586), PDE6C_CHICK (P52731), 
PDE6C_HUMAN (P51160), PDE6C_MOUSE (Q91ZQ1), PDE6_CAEEL  (Q9N2V9), 
PDE6_DROAN  (B3LVW5), PDE6_DROER  (B3P3K2), PDE6_DROGR  (B4JXX2), 
PDE6_DROME  (Q9VFI9), PDE6_DROMO  (B4K9L4), PDE6_DROPE  (B4G4E5), 
PDE6_DROPS  (Q298P4), PDE6_DROSE  (B4HEM4), PDE6_DROSI  (B4QZU1), 
PDE6_DROVI  (B4LVU6), PDE6_DROWI  (B4NAL6), PDE6_DROYA  (B4PSS5), 
PDE7A_HUMAN (Q13946), PDE7A_MOUSE (P70453), PDE7A_RAT   (O08593), 
PDE7B_HUMAN (Q9NP56), PDE7B_MOUSE (Q9QXQ1), PDE8A_HUMAN (O60658), 
PDE8A_MOUSE (O88502), PDE8B_HUMAN (O95263), PDE8B_MOUSE (E9Q4S1), 
PDE9A_HUMAN (O76083), PDE9A_MOUSE (O70628)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
PDE4A_CAVPO (O89085)
False positive hits (sequences which do not belong to the set under consideration):
DNAE2_BRAJA (Q89QU8)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		1F0J; 1JP1; 1JP2; 1LHQ; 1LRB; 1LRC; 1LXQ; 1LXR; 1LXS; 1LXU; 1LXW; 1LXX; 1MKD; 1OYN; 1PTW; 1Q9M; 1RKP; 1RO6; 1RO9; 1ROR; 1SO2; 1SOJ; 1T9S; 1TAZ; 1TB5; 1TB7; 1TBB; 1TBF; 1UDT; 1UDU; 1UHO; 1XLX; 1XLZ; 1XM4; 1XM6; 1XMU; 1XMY; 1XN0; 1XOM; 1XON; 1XOQ; 1XOR; 1XOS; 1XOT; 1XOZ; 1XP0; 1Y2B; 1Y2C; 1Y2D; 1Y2E; 1Y2H; 1Y2J; 1Y2K; 1Z1L; 1ZKL; 1ZKN; 2CHM; 2FM0; 2FM5; 2H40; 2H42; 2H44; 2HD1; 2O8H; 2OUN; 2OUP; 2OUQ; 2OUR; 2OUS; 2OUU; 2OVV; 2OVY; 2QYK; 2QYL; 2QYN; 2WEY; 2Y0J; 2YY2; 3BJC; 3D3P; 3DY8; 3DYL; 3DYN; 3DYQ; 3DYS; 3ECM; 3ECN; 3FRG; 3G3N; 3G45; 3G4G; 3G4I; 3G4K; 3G4L; 3G58; 3GWT; 3HC8; 3HDZ; 3HMV; 3HQW; 3HQY; 3HQZ; 3HR1; 3I8V; 3IAD; 3IAK; 3IBJ; 3ITM; 3ITU; 3JSI; 3JSW; 3JWQ; 3JWR; 3K3E; 3K3H; 3K4S; 3KKT; 3LXG; 3LY2; 3N3Z; 3O0J; 3O56; 3O57; 3QI3; 3QI4; 3QPN; 3QPO; 3QPP; 3SHY; 3SHZ; 3SL3; 3SL4; 3SL5; 3SL6; 3SL8; 3SN7; 3SNI; 3SNL; 3TGE;

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