Entry: PS00144

General information about the entry
Entry name ASN_GLN_ASE_1
Accession number PS00144
Entry type PATTERN
Date APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00132
Associated ProRule PRU10099
Name and characterization of the entry
DescriptionAsparaginase / glutaminase active site signature 1.
Pattern [LIVM]-x-{L}-T-G-G-T-[IV]-[AGS].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 122 hits in 122 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 51 hits in 51 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 71 hits in 71 different sequences
  • Number of known missed hits: 17
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 41.80 %
  • Recall (true hits / (true hits + false negatives)): 75.00 %
Comments
  • Taxonomic range: Archaea, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 7,active_site
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
ASP21_YEAST (P0CZ17), ASP22_YEAST (P0CX77), ASP23_YEAST (P0CX78), 
ASP24_YEAST (P0CX79), ASPG1_BACSU (P26900), ASPG1_ECO57 (P0A963), 
ASPG1_ECOLI (P0A962), ASPG1_YEAST (P38986), ASPG2_BACSU (O34482), 
ASPG2_ECOLI (P00805), ASPG2_HAEIN (P43843), ASPG_BACLI  (P30363), 
ASPG_DEIRA  (Q9RRX9), ASPG_DIRIM  (Q9U518), ASPG_ERWCH  (P06608), 
ASPG_HELPJ  (Q9ZLB9), ASPG_HELPY  (O25424), ASPG_MYCBO  (P63628), 
ASPG_MYCLE  (Q9X7E6), ASPG_MYCTU  (P63627), ASPG_WOLSU  (P50286), 
ASPQ_ACIGL  (P10172), ASPQ_DELAC  (P83712), ASPQ_PSEAE  (Q9I407), 
ASPQ_PSEFA  (O68897), ASPQ_PSEPK  (Q88K39), ASPQ_PSES7  (P10182), 
GATD_ARCFU  (O29380), GATD_HALS3  (B0R6H4), GATD_HALSA  (Q9HP20), 
GATD_HALWD  (Q18GL3), GATD_METAC  (Q8TR66), GATD_METBF  (Q46GJ6), 
GATD_METBU  (Q12X65), GATD_METJA  (Q60331), GATD_METKA  (Q8TV84), 
GATD_METM5  (A4FWR5), GATD_METM6  (A9AA46), GATD_METM7  (A6VGK5), 
GATD_METMA  (Q8PUM7), GATD_METMP  (P61400), GATD_METS3  (A5UK11), 
GATD_METST  (Q2NEH1), GATD_METTH  (O26802), GATD_METVS  (A6UPR4), 
GATD_PYRAB  (Q9V0T9), GATD_PYRFU  (Q8U0X0), GATD_PYRHO  (O59132), 
GATD_PYRKO  (Q5JI77), GATD_THEAC  (Q9HJJ5), GATD_THEVO  (Q979L8)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
GATD_AERPE  (Q9Y9T8), GATD_METS5  (A4YHH3), GATD_NANEQ  (P61401), 
GATD_PYRAE  (Q8ZY04), GATD_SULAC  (Q4J955), GATD_SULIA  (C3N5E7), 
GATD_SULIK  (C4KH13), GATD_SULIL  (C3MPS1), GATD_SULIM  (C3MYR5), 
GATD_SULIN  (C3NHQ2), GATD_SULIY  (C3NE01), GATD_SULSO  (Q97ZH5), 
GATD_SULTO  (Q971W5), GATD_THEPD  (A1RX40), LPP60_HUMAN (Q86U10), 
LPP60_MOUSE (A0JNU3), LPP60_RAT   (O88202)
False positive hits (sequences which do not belong to the set under consideration):
API10_SOLTU (Q03197), API11_SOLTU (P16348), API1_SOLTU  (Q41480), 
API2_SOLTU  (Q43646), API3_SOLTU  (P58518), API4_SOLTU  (Q43645), 
API5_SOLTU  (P58519), API6_SOLTU  (P58520), API7_SOLTU  (Q41448), 
API8_SOLTU  (P17979), API9_SOLTU  (P58521), APT_BLOPB   (Q493A5), 
APT_CHLAA   (A9WCV7), APT_CLOB1   (A7FY09), APT_CLOBH   (A5I6E1), 
APT_CLOBK   (B1IME3), APT_CLOBL   (A7GHS8), APT_CLOBM   (B1L0A2), 
APT_CLOP1   (Q0TP22), APT_CLOPE   (Q8XJ22), APT_CLOPS   (Q0SRP2), 
APT_DESRM   (A4J2G8), APT_LACBA   (Q03QP8), APT_LACC3   (Q038P1), 
APT_LACLA   (Q9CHT5), APT_LACLM   (A2RIW0), APT_LACLS   (Q031A0), 
APT_LACPL   (Q88VH0), APT_LACS1   (Q1WT53), APT_LACSS   (Q38W53), 
APT_METM7   (A6VJW6), APT_MYCBO   (P59959), APT_MYCBP   (A1KLT2), 
APT_MYCSJ   (A3PYX7), APT_MYCSK   (A1UFB6), APT_MYCSS   (Q1B9P7), 
APT_MYCTA   (A5U5T4), APT_MYCTU   (Q50637), APT_PEDPA   (Q03F39), 
APT_PELCD   (Q3A4N0), APT_PROM5   (A2BXB1), APT_ROSCS   (A7NG77), 
APT_ROSS1   (A5URA4), APT_UREP2   (B1AJC8), APT_UREPA   (Q9PQ02), 
ATM1_CHAGB  (Q2HIE9), ATRN1_MOUSE (Q6A051), KPRS2_ARCFU (O28853), 
KPRS_AERPE  (Q9YAW0), KPRS_COREF  (Q8FQV2), KPRS_CORGL  (Q8NRU9), 
KPRS_MYCBO  (P65233), KPRS_MYCLE  (Q9CD45), KPRS_MYCTU  (P65232), 
KPRS_NOSS1  (Q8YN97), KPRS_THEAC  (Q9HLV6), KPRS_THEVO  (Q97CA5), 
MACB_NITEU  (Q82VK1), PPR4_ARATH  (Q9FZ24), ROCO5_DICDI (Q1ZXD6), 
SPI1_SOLTU  (P58514), SPI2_SOLTU  (P58515), SPI4_SOLTU  (P58517), 
SPI5_SOLTU  (Q41484), SPI6_SOLTU  (Q41433), SPI7_SOLTU  (P30941), 
SPIKE_ADECT (Q65914), Y1519_RHILW (B5ZMI8), Y1668_ARATH (Q9C9N5), 
Y2074_RHIL3 (Q1MHJ7), YCGA_BACSU  (P55908)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AGX; 1DJO; 1DJP; 1HFJ; 1HFK; 1HFW; 1HG0; 1HG1; 1HO3; 1IHD; 1JAZ; 1JJA; 1JSL; 1JSR; 1NNS; 1O7J; 1WSA; 1ZQ1; 2D6F; 2HIM; 2P2D; 2P2N; 2WLT; 2WT4; 3ECA; 3PGA; 4PGA;

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