Entry: PS00165

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General information about the entry

Entry name [info] DEHYDRATASE_SER_THR
Accession [info] PS00165
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00149

Name and characterization of the entry

Description [info] Serine/threonine dehydratases pyridoxal-phosphate attachment site.
Pattern [info]
[DESH]-x(4,5)-[STVG]-{EVKD}-[AS]-[FYI]-K-[DLIFSA]-[RLVMF]-[GA]-[LIVMGA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 214 in 214 different sequences
Number of true positive hits 186 in 186 different sequences
Number of 'unknown' hits
Number of false positive hits 28 in 28 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 86.92 %
Recall (true positives / (true positives + false negatives)) 90.73 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
186 sequences

ILVA_BACHD  (Q9KC63), ILVA_BACSU  (P37946), ILVA_BURM1  (P53607), 
ILVA_CORGL  (Q04513), ILVA_ECOLI  (P04968), ILVA_HAEIN  (P46493), 
ILVA_LACLA  (Q02145), ILVA_MYCBO  (P66898), ILVA_MYCLE  (Q9X7F1), 
ILVA_MYCTO  (P9WG94), ILVA_MYCTU  (P9WG95), ILVA_PASMU  (Q9CKJ2), 
ILVA_SALTY  (P20506), ILVA_STAA3  (Q2FF63), ILVA_STAA8  (Q2FWJ9), 
ILVA_STAAB  (Q2YUE8), ILVA_STAAC  (Q5HEE0), ILVA_STAAM  (Q99SJ1), 
ILVA_STAAN  (Q7A4H2), ILVA_STAAR  (Q3V7T5), ILVA_STAAS  (Q3V7T4), 
ILVA_STAAW  (Q8NVI8), ILVA_STAEQ  (Q5HMF5), ILVA_STAES  (Q8CNK9), 
ILVA_STAHJ  (Q4L7U4), ILVA_STAS1  (Q49Z16), SDH1_YEASX  (P0CF23), 
SDHD1_ECOL5 (Q0TF95), SDHD1_ECOUT (Q1R901), SDHD2_ECOL5 (Q0T953), 
SDHD2_ECOUT (Q1R2Q6), SDHD_ACIAD  (Q6FDC1), SDHD_ACIB5  (B7I8P7), 
SDHD_ACIBC  (B2HVC6), SDHD_ACIBT  (A3M3B1), SDHD_AERHH  (A0KI76), 
SDHD_AERS4  (A4SPX2), SDHD_BACAC  (C3L7G5), SDHD_BACAH  (A0RCF8), 
SDHD_BACAN  (Q81S85), SDHD_BACC1  (Q73AC5), SDHD_BACC2  (B7IR88), 
SDHD_BACC3  (C1EPF1), SDHD_BACC4  (B7HID8), SDHD_BACC7  (B7HMG6), 
SDHD_BACCR  (Q81F73), SDHD_BACCZ  (Q63D23), SDHD_BACHD  (Q9KC12), 
SDHD_BACHK  (Q6HKG3), SDHD_BACSK  (Q5WGL6), SDHD_BACSU  (P54555), 
SDHD_BACWK  (A9VPH9), SDHD_CHRVO  (Q7NUP9), SDHD_CITK8  (A8ACI7), 
SDHD_COLP3  (Q47V69), SDHD_DESHY  (Q24WR0), SDHD_ECO24  (A7ZPH2), 
SDHD_ECO45  (B7MH26), SDHD_ECO55  (B7LBR9), SDHD_ECO57  (Q8XCK5), 
SDHD_ECO5E  (B5YYW7), SDHD_ECO81  (B7MY25), SDHD_ECO8A  (B7M6N5), 
SDHD_ECOBW  (C4ZVQ3), SDHD_ECODH  (B1X9N9), SDHD_ECOHS  (A8A2M0), 
SDHD_ECOK1  (A1ADP3), SDHD_ECOL6  (Q8FFF4), SDHD_ECOLC  (B1IX96), 
SDHD_ECOLI  (P00926), SDHD_ECOLU  (B7N5W6), SDHD_ECOSE  (B6I6R7), 
SDHD_ESCF3  (B7LK20), SDHD_GEOKA  (Q75TC9), SDHD_GEOSE  (Q75TH5), 
SDHD_HISS1  (Q0I5V1), SDHD_HISS2  (B0UWV3), SDHD_LACF3  (B2GBP8), 
SDHD_LACPL  (Q88TY1), SDHD_OENOB  (Q04G28), SDHD_PEDPA  (Q03DF6), 
SDHD_PHOLL  (Q7N5H9), SDHD_PHOPR  (Q6LHF5), SDHD_PSEA7  (A6V271), 
SDHD_PSEA8  (B7V2Y0), SDHD_PSEAB  (Q02QJ1), SDHD_PSEAE  (Q9HYN9), 
SDHD_PSEMY  (A4XXF3), SDHD_PSEP1  (A5W4Y8), SDHD_PSEPG  (B0KGK3), 
SDHD_SALA4  (B5EY75), SDHD_SALAR  (A9MKH2), SDHD_SALCH  (Q57I32), 
SDHD_SALDC  (B5FMC1), SDHD_SALEP  (B5QU31), SDHD_SALG2  (B5RG23), 
SDHD_SALHS  (B4TA53), SDHD_SALNS  (B4SY68), SDHD_SALPA  (Q5PKR3), 
SDHD_SALPB  (A9MWI4), SDHD_SALPC  (C0Q241), SDHD_SALPK  (B5BII6), 
SDHD_SALSV  (B4TMW9), SDHD_SALTI  (Q8Z2L4), SDHD_SALTY  (Q8ZL08), 
SDHD_SERP5  (A8GES6), SDHD_SHIBS  (Q31YA5), SDHD_SHIDS  (Q32DH8), 
SDHD_SHIF8  (Q0T2D1), SDHD_SHIFL  (Q83MK8), SDHD_SHISS  (Q3YZG4), 
SDHD_STAS1  (Q4A041), SDHD_VIBC3  (A5F0M6), SDHD_VIBCB  (A7MYG2), 
SDHD_VIBCH  (Q9KL72), SDHD_VIBCM  (C3LWD9), SDHD_VIBPA  (Q87QA2), 
SDHD_YERE8  (A1JJW5), SDHL_BOVIN  (Q0VCW4), SDHL_DICDI  (Q86B06), 
SDHL_HUMAN  (P20132), SDHL_MOUSE  (Q8VBT2), SDHL_RAT    (P09367), 
SDHL_YEAS1  (B3LU13), SDHL_YEAS6  (B5VKE8), SDHL_YEAS7  (A6ZVB1), 
SDHL_YEAS8  (C8ZAU6), SDSL_HUMAN  (Q96GA7), SRR_ARATH   (Q2PGG3), 
SRR_BOVIN   (A0JNI4), SRR_HUMAN   (Q9GZT4), SRR_MOUSE   (Q9QZX7), 
SRR_RAT     (Q76EQ0), SRY1_YEAST  (P36007), STDH_YEAST  (P25379), 
TDCB_ECO57  (P0AGF8), TDCB_ECOL6  (P0AGF7), TDCB_ECOLI  (P0AGF6), 
TDCB_SALTY  (P11954), TDCB_SHIFL  (P0AGF9), TDCB_STAA3  (Q2FH01), 
TDCB_STAA8  (Q2FYJ3), TDCB_STAAB  (Q2YY67), TDCB_STAAC  (Q5HFY5), 
TDCB_STAAM  (Q99U50), TDCB_STAAN  (Q7A5L8), TDCB_STAAR  (Q6GGX0), 
TDCB_STAAS  (Q6G9C4), TDCB_STAAW  (Q8NWQ4), THD1_ARATH  (Q9ZSS6), 
THD1_SOLLC  (P25306), THDH_BLAAD  (O42615), THDH_SCHPO  (O94634), 
THDH_YEAST  (P00927), THNS2_DANRE (Q2YDP8), THNS2_XENLA (Q5XH07), 
THRC1_ARATH (Q9S7B5), THRC2_ARATH (Q9SSP5), THRC_ASHGO  (Q00063), 
THRC_BACHD  (Q9K7E3), THRC_BACSL  (P09123), THRC_BACSU  (P04990), 
THRC_BUCAI  (P57289), THRC_BUCAP  (Q8K9V1), THRC_BUCBP  (Q89AR5), 
THRC_CORGL  (P23669), THRC_ECOLI  (P00934), THRC_HAEIN  (P44503), 
THRC_HELPJ  (Q9ZMX5), THRC_HELPY  (O24924), THRC_METAC  (Q8TQD4), 
THRC_METGL  (P37145), THRC_METJA  (Q58860), THRC_MYCBO  (P66903), 
THRC_MYCLE  (P45837), THRC_MYCS2  (A0R220), THRC_MYCTO  (P9WG58), 
THRC_MYCTU  (P9WG59), THRC_PSEAE  (P29363), THRC_SCHPO  (Q42598), 
THRC_SERMA  (P27735), THRC_SOLTU  (Q9MT28), THRC_SYNY3  (P74193), 
THRC_YEAST  (P16120), Y4TJ_RHISN  (P55664), YI168_YEAST (P0CF21)
» More

UniProtKB/Swiss-Prot
False negative sequences
19 sequences

SDHD_ACIAC  (A1TPW5), SDHD_ACIET  (B9MIR7), SDHD_ACISJ  (A1W838), 
SDHD_BURP0  (A3P975), SDHD_BURP1  (Q3JJ76), SDHD_BURP6  (A3NNQ0), 
SDHD_BURPS  (Q63IF8), SDHD_BURS3  (Q396Y3), SDHD_BURTA  (Q2T8Q2), 
SDHD_CARHZ  (Q3AFZ5), SDHD_CUPPJ  (Q46X58), SDHD_FUSNN  (Q8RFX6), 
SDHD_HAHCH  (Q2SHX7), SDHD_POLNA  (A1VWK8), SDHD_RHIE6  (B3PYT5), 
SDHD_RHILW  (B5ZNC1), SDHD_SINMW  (A6UB95), SRR_SCHPO   (O59791), 
THD1_CICAR  (Q39469)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

THD1_SOLTU  (P31212)

		
UniProtKB/Swiss-Prot
False positive sequences
28 sequences

ACTN3_BOVIN (Q0III9), ACTN3_HUMAN (Q08043), ACTN3_MOUSE (O88990), 
ALKD_PSEPU  (P00885), AROE_PYRAE  (Q8ZW89), BFPB_ECO11  (Q9S142), 
BFPB_ECO27  (Q47068), CY551_ALLVD (P80549), CY551_PSEAE (P00099), 
CYSM_CAMJE  (P71128), DHOM_HELPJ  (Q9ZL20), DHOM_HELPY  (P56429), 
DIP2A_MOUSE (Q8BWT5), DNLJ_BEII9  (B2IGH4), FEOB_LEPIC  (Q72SI0), 
FEOB_LEPIN  (Q8F332), GCST_PSESM  (Q88AS0), HNRLL_HUMAN (Q8WVV9), 
HNRLL_MOUSE (Q921F4), KAS1_STRVN  (P16540), PALLD_HUMAN (Q8WX93), 
PLSP2_LOTGI (B3A0P3), RL15_AGRT5  (Q8UE36), RS20_CUPPJ  (Q46XK7), 
RS20_RALME  (Q1LJ99), RSMG_CLOB8  (A6M3M3), SYLC_DICDI  (Q54N83), 
YDHG_SCHPO  (Q92361)
» More

PDB
[Detailed view]
15 PDB

1KL7; 1P5J; 1PWE; 1PWH; 1TDJ; 1VB3; 2D1F; 2RKB; 3HMK; 3L6B; 3L6C; 3R0X; 3R0Z; 3SS7; 3SS9
» More

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