Entry: PS00433

Forthcoming changes to the profile format
General information about the entry

Entry name [info] PHOSPHOFRUCTOKINASE
Accession [info] PS00433
Entry type [info] PATTERN
Date [info] NOV-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00336

Name and characterization of the entry

Description [info] Phosphofructokinase signature.
Pattern [info]
[RK]-x(4)-[GAS]-H-x-[QL]-[QR]-[GS]-[GF]-x(5)-[DE]-[RL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 330 in 296 different sequences
Number of true positive hits 330 in 296 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 13
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.21 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] substrate_binding at position 1
Site [info] substrate_binding at position 4
Site [info] substrate_binding at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
296 sequences

K6PF1_ASPOR (Q9HGZ1), K6PF1_BACTN (Q8A8R5), K6PF1_CANAX (O94201), 
K6PF1_ECO57 (P0A797), K6PF1_ECOL6 (Q8FBD0), K6PF1_ECOLI (P0A796), 
K6PF1_KLULA (Q03215), K6PF1_NOSS1 (Q8YKG3), K6PF1_PICPA (Q92448), 
K6PF1_SHIFL (P0A798), K6PF1_STRCO (O08333), K6PF1_SYNY3 (P72830), 
K6PF1_THET8 (P21777), K6PF1_YARLI (P59680), K6PF1_YEAST (P16861), 
K6PF2_ASPOR (Q9HGZ0), K6PF2_BACTN (Q8A624), K6PF2_CANAX (O94200), 
K6PF2_CLOPE (Q8XL57), K6PF2_KLULA (Q03216), K6PF2_NOSS1 (Q8YVR1), 
K6PF2_STRCO (Q9L1L8), K6PF2_SYNY3 (Q55988), K6PF2_YEAST (P16862), 
K6PF3_STRCO (Q9FC99), K6PF_ACTP2  (A3N1C8), K6PF_ACTP7  (B3GY11), 
K6PF_ACTPJ  (B0BQ64), K6PF_ACTSZ  (A6VM63), K6PF_ALISL  (B6EMS4), 
K6PF_ALKMQ  (A6TVD3), K6PF_ALKOO  (A8MLY0), K6PF_ANAVT  (Q3M8N2), 
K6PF_ANOFW  (B7GGT1), K6PF_AQUAE  (O67605), K6PF_ASPFU  (Q4W9B8), 
K6PF_ASPNG  (P78985), K6PF_BACA2  (A7Z7K6), K6PF_BACAA  (C3PAI8), 
K6PF_BACAC  (C3L8X8), K6PF_BACAH  (A0RJJ6), K6PF_BACAN  (Q81KZ0), 
K6PF_BACC0  (B7JRX2), K6PF_BACC1  (Q72ZD8), K6PF_BACC2  (B7IJZ8), 
K6PF_BACC3  (C1EUU3), K6PF_BACC4  (B7HFB3), K6PF_BACC7  (B7HRN9), 
K6PF_BACCE  (Q4MVY3), K6PF_BACCN  (A7GTP4), K6PF_BACCQ  (B9J099), 
K6PF_BACCR  (Q817F3), K6PF_BACCZ  (Q633J8), K6PF_BACHD  (Q9K843), 
K6PF_BACHK  (Q6HCT3), K6PF_BACLD  (Q65G82), K6PF_BACP2  (A8FG55), 
K6PF_BACSK  (Q5WEF6), K6PF_BACSU  (O34529), K6PF_BACWK  (A9VJR1), 
K6PF_BAUCH  (Q1LTT2), K6PF_BLOFL  (Q7VRK9), K6PF_BOVIN  (Q0IIG5), 
K6PF_BREBN  (C0Z7W7), K6PF_BUCA5  (B8D996), K6PF_BUCAI  (P57391), 
K6PF_BUCAP  (Q8K9N0), K6PF_BUCAT  (B8D7J8), K6PF_BUCBP  (P59563), 
K6PF_BUCCC  (Q057P0), K6PF_CAEEL  (Q27483), K6PF_CANFA  (P52784), 
K6PF_CHLAA  (A9WCU2), K6PF_CHLAD  (B8GAA4), K6PF_CHLSY  (B9LHK4), 
K6PF_CITK8  (A8AL13), K6PF_CLOAB  (O08308), K6PF_CLOB1  (A7FYW7), 
K6PF_CLOB6  (C3KV06), K6PF_CLOBA  (B2UZX8), K6PF_CLOBB  (B2TQR6), 
K6PF_CLOBH  (A5I798), K6PF_CLOBJ  (C1FM55), K6PF_CLOBK  (B1IFV9), 
K6PF_CLOBL  (A7GIW9), K6PF_CLOBM  (B1L266), K6PF_CLOD6  (Q180P4), 
K6PF_CLONN  (A0PYC8), K6PF_CLOTE  (Q890Z2), K6PF_COREF  (Q8RQN5), 
K6PF_CORGL  (Q8NR14), K6PF_COXBU  (Q83EH9), K6PF_CROS8  (A7MQ83), 
K6PF_CYTH3  (Q11RE2), K6PF_DEIRA  (Q9RWN1), K6PF_DICDI  (P90521), 
K6PF_DROME  (P52034), K6PF_ECO24  (A7ZUC9), K6PF_ECO27  (B7UNN6), 
K6PF_ECO45  (B7MI48), K6PF_ECO55  (B7LA13), K6PF_ECO5E  (B5YZ53), 
K6PF_ECO7I  (B7NU91), K6PF_ECO81  (B7N2Q7), K6PF_ECO8A  (B7M6W7), 
K6PF_ECOBW  (C5A083), K6PF_ECODH  (B1XB82), K6PF_ECOHS  (A8A720), 
K6PF_ECOL5  (Q0TAE8), K6PF_ECOLC  (B1IVG3), K6PF_ECOLU  (B7NFL3), 
K6PF_ECOSE  (B6I4Q8), K6PF_ECOSM  (B1LNL9), K6PF_EDWI9  (C5BC26), 
K6PF_ENT38  (A4WG81), K6PF_ENTCL  (Q9Z6C3), K6PF_ERWT9  (B2VF62), 
K6PF_ESCF3  (B7LVC9), K6PF_FINM2  (B0S230), K6PF_FUSNN  (Q8RG98), 
K6PF_GEOKA  (Q5KWB1), K6PF_GEOSE  (P00512), K6PF_GEOSW  (C5D663), 
K6PF_HAECO  (Q27665), K6PF_HAEDU  (Q8GNC1), K6PF_HAEI8  (Q4QLS8), 
K6PF_HAEIE  (A5UD89), K6PF_HAEIN  (P43863), K6PF_HAEPS  (B8F8G9), 
K6PF_HALOH  (B8D1K5), K6PF_HAMD5  (C4K7E1), K6PF_HISS1  (Q0I267), 
K6PF_HISS2  (B0UW05), K6PF_HORSE  (Q867C9), K6PF_HUMAN  (P08237), 
K6PF_KLEP3  (B5XZ40), K6PF_KLEP7  (A6TGB8), K6PF_LACAC  (Q5FKG6), 
K6PF_LACDE  (P80019), K6PF_LACGA  (Q043V2), K6PF_LACH4  (A8YV22), 
K6PF_LACJO  (Q74JM8), K6PF_LACLA  (Q07636), K6PF_LACLM  (A2RKA2), 
K6PF_LACLS  (Q02YK5), K6PF_LACPL  (Q88VY1), K6PF_LACS1  (Q1WTT3), 
K6PF_LISIN  (Q92BE4), K6PF_LISMC  (C1KVL8), K6PF_LISMF  (Q71Z96), 
K6PF_LISMH  (B8DHH7), K6PF_LISMO  (Q8Y6W0), K6PF_LISW6  (A0AJ20), 
K6PF_LYSSH  (Q93LR4), K6PF_MACCJ  (B9E7A4), K6PF_MACFA  (Q60HD9), 
K6PF_MANSM  (Q65VM6), K6PF_MOUSE  (P47857), K6PF_MYCBO  (P65691), 
K6PF_MYCCT  (Q2SSQ6), K6PF_MYCH2  (Q601D3), K6PF_MYCH7  (Q4A8Q3), 
K6PF_MYCHJ  (Q4AAM2), K6PF_MYCLE  (O33106), K6PF_MYCMO  (Q6KHX0), 
K6PF_MYCPU  (Q98PW8), K6PF_MYCTO  (P9WID6), K6PF_MYCTU  (P9WID7), 
K6PF_NATTJ  (B2A6Y0), K6PF_OCEIH  (Q8EPD6), K6PF_PAEMC  (Q59214), 
K6PF_PASMU  (Q9CPH2), K6PF_PECAS  (Q6CZ46), K6PF_PECCP  (C6DHK2), 
K6PF_PEDPA  (Q03F74), K6PF_PHOPR  (Q6LVK2), K6PF_PIG    (Q2HYU2), 
K6PF_PONAB  (Q5RAG9), K6PF_RABIT  (P00511), K6PF_RAT    (P47858), 
K6PF_SALA4  (B5F0P6), K6PF_SALAR  (A9MI50), K6PF_SALCH  (Q57HF3), 
K6PF_SALDC  (B5FPR2), K6PF_SALEP  (B5QWZ5), K6PF_SALG2  (B5RFA9), 
K6PF_SALHS  (B4TCK0), K6PF_SALNS  (B4T049), K6PF_SALPA  (Q5PIR6), 
K6PF_SALPB  (A9MZE7), K6PF_SALPC  (C0Q414), K6PF_SALPK  (B5BJI2), 
K6PF_SALSV  (B4TPS6), K6PF_SALTI  (P65693), K6PF_SALTY  (P65692), 
K6PF_SCHMA  (Q27778), K6PF_SCHPO  (O42938), K6PF_SERP5  (A8GLB0), 
K6PF_SHIB3  (B2TVQ8), K6PF_SHIBS  (Q31U74), K6PF_SHIDS  (Q32A80), 
K6PF_SHISS  (Q3YV62), K6PF_SODGM  (Q2NQX2), K6PF_SPICI  (P20275), 
K6PF_STAA2  (A6U2G5), K6PF_STAA9  (A5ITM2), K6PF_STAAB  (Q2YTE2), 
K6PF_STAAC  (Q5HF75), K6PF_STAAE  (A6QHN3), K6PF_STAAM  (P65694), 
K6PF_STAAN  (P99165), K6PF_STAAR  (Q6GG08), K6PF_STAAS  (Q6G8M8), 
K6PF_STAAT  (A8Z2L4), K6PF_STAAW  (P65695), K6PF_STACT  (B9DN94), 
K6PF_STAEQ  (Q5HNK6), K6PF_STAES  (Q8CS68), K6PF_STRA1  (Q3K1E6), 
K6PF_STRA3  (P65696), K6PF_STRA5  (P65697), K6PF_STRE4  (C0M8V6), 
K6PF_STREM  (B4U2M2), K6PF_STRGC  (A8AXW1), K6PF_STRMU  (Q8DTX6), 
K6PF_STRP1  (Q99ZD0), K6PF_STRP2  (Q04L24), K6PF_STRP3  (P0DD02), 
K6PF_STRP4  (B5E3Z8), K6PF_STRP6  (Q5XBV2), K6PF_STRP7  (C1C6M8), 
K6PF_STRP8  (Q8P0S6), K6PF_STRPB  (Q1JBF7), K6PF_STRPC  (Q1JLD9), 
K6PF_STRPD  (Q1JGH6), K6PF_STRPF  (Q1J694), K6PF_STRPG  (A2RE65), 
K6PF_STRPI  (B1IB66), K6PF_STRPJ  (B8ZNU0), K6PF_STRPM  (Q48T86), 
K6PF_STRPN  (Q97RC6), K6PF_STRPQ  (P0DD03), K6PF_STRPS  (B2IP53), 
K6PF_STRPZ  (B5XLV6), K6PF_STRR6  (Q8DQ85), K6PF_STRS7  (C0MGJ9), 
K6PF_STRSV  (A3CM69), K6PF_STRSY  (A4VTS0), K6PF_STRU0  (B9DSA4), 
K6PF_STRZJ  (C1CDP4), K6PF_STRZP  (C1CJY4), K6PF_STRZT  (C1CRZ7), 
K6PF_SULDN  (Q30T53), K6PF_SULNB  (A6QAB4), K6PF_TERTT  (C5BNR1), 
K6PF_THEEB  (Q8DJB1), K6PF_THEMA  (Q9WY52), K6PF_THENN  (B9K6R9), 
K6PF_THEP1  (A5IKL2), K6PF_THEP3  (B0K7U7), K6PF_THEPX  (B0K6L2), 
K6PF_THESQ  (B1L9U3), K6PF_THET2  (Q72H98), K6PF_THETN  (Q8R914), 
K6PF_TOLAT  (C4LEQ5), K6PF_VIBCB  (A7MX59), K6PF_VIBCH  (Q9KNP2), 
K6PF_VIBF1  (Q5E2B1), K6PF_VIBFM  (B5FBT1), K6PF_VIBPA  (Q87KX0), 
K6PF_VIBVU  (Q8DCY1), K6PF_VIBVY  (Q7MGW6), K6PF_WOLSU  (Q7M9C2), 
K6PF_YERE8  (A1JHZ3), K6PF_YERP3  (A7FCW1), K6PF_YERPA  (Q1C297), 
K6PF_YERPB  (B2JZA3), K6PF_YERPE  (Q8ZJL6), K6PF_YERPG  (A9R6A3), 
K6PF_YERPN  (Q1CD33), K6PF_YERPP  (A4TSA7), K6PF_YERPS  (Q66GA8), 
K6PF_YERPY  (B1JQU4), K6PL_BOVIN  (A1A4J1), K6PL_HUMAN  (P17858), 
K6PL_MOUSE  (P12382), K6PL_PONAB  (Q5R7V5), K6PL_RAT    (P30835), 
K6PP_HUMAN  (Q01813), K6PP_MOUSE  (Q9WUA3), K6PP_PONAB  (Q5R636), 
K6PP_RABIT  (P47859), K6PP_RAT    (P47860), PFP_AMYME   (Q59126), 
PFP_AMYMS   (Q9AGC0), PFP_DICTH   (Q9KH71)
» More

UniProtKB/Swiss-Prot
False negative sequences
13 sequences

K6PF1_CLOPE (Q8XNH2), K6PF3_BACTN (Q8A2E9), K6PF_ENTFA  (Q836R3), 
K6PF_LACC3  (Q039I0), K6PF_LACCB  (B3WE64), K6PF_MYCGE  (P47457), 
K6PF_MYCPE  (Q8EVH2), K6PF_MYCPN  (P75476), K6PF_PERMH  (C0QQX4), 
K6PF_STRTD  (Q03KB7), K6PF_STRTR  (Q9L9E3), K6PF_SULSY  (B2V7W7), 
K6PF_UREPA  (Q9PQV8)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

K6PF2_THET8 (P21778), K6PF_CALFI  (Q27543)

		
PDB
[Detailed view]
15 PDB

1MTO; 1PFK; 1ZXX; 2PFK; 3O8L; 3O8N; 3O8O; 3PFK; 3U39; 4A3S; 4I36; 4I4I; 4I7E; 4PFK; 6PFK
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission