Entry: PS00433

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General information about the entry

Entry name [info] PHOSPHOFRUCTOKINASE
Accession [info] PS00433
Entry type [info] PATTERN
Date [info] NOV-1990 (CREATED); APR-2006 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00336

Name and characterization of the entry

Description [info] Phosphofructokinase signature.
Pattern [info]
[RK]-x(4)-[GAS]-H-x-[QL]-[QR]-[GS]-[GF]-x(5)-[DE]-[RL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 336 in 300 different sequences
Number of true positive hits 336 in 300 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 16
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.45 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] substrate_binding at position 1
Site [info] substrate_binding at position 4
Site [info] substrate_binding at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
300 sequences

PFKA1_ASPOR (Q9HGZ1), PFKA1_BACTN (Q8A8R5), PFKA1_CAEEL (Q9TZL8), 
PFKA1_CANAX (O94201), PFKA1_KLULA (Q03215), PFKA1_NOSS1 (Q8YKG3), 
PFKA1_PICPA (Q8NJU8), PFKA1_PICPG (Q92448), PFKA1_SYNY3 (P72830), 
PFKA1_THET8 (P21777), PFKA1_YEAST (P16861), PFKA2_ASPOR (Q9HGZ0), 
PFKA2_BACTN (Q8A624), PFKA2_CAEEL (Q27483), PFKA2_CANAX (O94200), 
PFKA2_CLOPE (Q8XL57), PFKA2_KLULA (Q03216), PFKA2_NOSS1 (Q8YVR1), 
PFKA2_PICPA (Q8TGA0), PFKA2_PICPG (C4QXA5), PFKA2_STRCO (Q9L1L8), 
PFKA2_SYNY3 (Q55988), PFKA2_YEAST (P16862), PFKA3_STRCO (Q9FC99), 
PFKAL_BOVIN (A1A4J1), PFKAL_HUMAN (P17858), PFKAL_MOUSE (P12382), 
PFKAL_PONAB (Q5R7V5), PFKAL_RAT   (P30835), PFKAM_BOVIN (Q0IIG5), 
PFKAM_CANFA (P52784), PFKAM_HORSE (Q867C9), PFKAM_HUMAN (P08237), 
PFKAM_MACFA (Q60HD9), PFKAM_MOUSE (P47857), PFKAM_PIG   (Q2HYU2), 
PFKAM_PONAB (Q5RAG9), PFKAM_RABIT (P00511), PFKAM_RAT   (P47858), 
PFKAP_HUMAN (Q01813), PFKAP_MOUSE (Q9WUA3), PFKAP_PONAB (Q5R636), 
PFKAP_RABIT (P47859), PFKAP_RAT   (P47860), PFKA_ACTP2  (A3N1C8), 
PFKA_ACTP7  (B3GY11), PFKA_ACTPJ  (B0BQ64), PFKA_ACTSZ  (A6VM63), 
PFKA_ALISL  (B6EMS4), PFKA_ALKMQ  (A6TVD3), PFKA_ALKOO  (A8MLY0), 
PFKA_ANAVT  (Q3M8N2), PFKA_ANOFW  (B7GGT1), PFKA_AQUAE  (O67605), 
PFKA_ASPFU  (Q4W9B8), PFKA_ASPNG  (P78985), PFKA_BACA2  (A7Z7K6), 
PFKA_BACAA  (C3PAI8), PFKA_BACAC  (C3L8X8), PFKA_BACAH  (A0RJJ6), 
PFKA_BACAN  (Q81KZ0), PFKA_BACC0  (B7JRX2), PFKA_BACC1  (Q72ZD8), 
PFKA_BACC2  (B7IJZ8), PFKA_BACC3  (C1EUU3), PFKA_BACC4  (B7HFB3), 
PFKA_BACC7  (B7HRN9), PFKA_BACCE  (Q4MVY3), PFKA_BACCN  (A7GTP4), 
PFKA_BACCQ  (B9J099), PFKA_BACCR  (Q817F3), PFKA_BACCZ  (Q633J8), 
PFKA_BACHD  (Q9K843), PFKA_BACHK  (Q6HCT3), PFKA_BACLD  (Q65G82), 
PFKA_BACP2  (A8FG55), PFKA_BACSK  (Q5WEF6), PFKA_BACSU  (O34529), 
PFKA_BACWK  (A9VJR1), PFKA_BAUCH  (Q1LTT2), PFKA_BLOFL  (Q7VRK9), 
PFKA_BREBN  (C0Z7W7), PFKA_BUCA5  (B8D996), PFKA_BUCAI  (P57391), 
PFKA_BUCAP  (Q8K9N0), PFKA_BUCAT  (B8D7J8), PFKA_BUCBP  (P59563), 
PFKA_BUCCC  (Q057P0), PFKA_CHLAA  (A9WCU2), PFKA_CHLAD  (B8GAA4), 
PFKA_CHLSY  (B9LHK4), PFKA_CITK8  (A8AL13), PFKA_CLOAB  (O08308), 
PFKA_CLOB1  (A7FYW7), PFKA_CLOB6  (C3KV06), PFKA_CLOBA  (B2UZX8), 
PFKA_CLOBB  (B2TQR6), PFKA_CLOBH  (A5I798), PFKA_CLOBJ  (C1FM55), 
PFKA_CLOBK  (B1IFV9), PFKA_CLOBL  (A7GIW9), PFKA_CLOBM  (B1L266), 
PFKA_CLONN  (A0PYC8), PFKA_CLOTE  (Q890Z2), PFKA_COREF  (Q8RQN5), 
PFKA_CORGL  (Q8NR14), PFKA_COXBU  (Q83EH9), PFKA_CROS8  (A7MQ83), 
PFKA_CYTH3  (Q11RE2), PFKA_DEIRA  (Q9RWN1), PFKA_DICDI  (P90521), 
PFKA_DROME  (P52034), PFKA_ECO24  (A7ZUC9), PFKA_ECO27  (B7UNN6), 
PFKA_ECO45  (B7MI48), PFKA_ECO55  (B7LA13), PFKA_ECO57  (P0A797), 
PFKA_ECO5E  (B5YZ53), PFKA_ECO7I  (B7NU91), PFKA_ECO81  (B7N2Q7), 
PFKA_ECO8A  (B7M6W7), PFKA_ECOBW  (C5A083), PFKA_ECODH  (B1XB82), 
PFKA_ECOHS  (A8A720), PFKA_ECOL5  (Q0TAE8), PFKA_ECOL6  (Q8FBD0), 
PFKA_ECOLC  (B1IVG3), PFKA_ECOLI  (P0A796), PFKA_ECOLU  (B7NFL3), 
PFKA_ECOSE  (B6I4Q8), PFKA_ECOSM  (B1LNL9), PFKA_EDWI9  (C5BC26), 
PFKA_ENT38  (A4WG81), PFKA_ENTCL  (Q9Z6C3), PFKA_ERWT9  (B2VF62), 
PFKA_ESCF3  (B7LVC9), PFKA_FINM2  (B0S230), PFKA_FUSNN  (Q8RG98), 
PFKA_GEOKA  (Q5KWB1), PFKA_GEOSE  (P00512), PFKA_GEOSW  (C5D663), 
PFKA_HAECO  (Q27665), PFKA_HAEDU  (Q8GNC1), PFKA_HAEI8  (Q4QLS8), 
PFKA_HAEIE  (A5UD89), PFKA_HAEIN  (P43863), PFKA_HAEPS  (B8F8G9), 
PFKA_HALOH  (B8D1K5), PFKA_HAMD5  (C4K7E1), PFKA_HISS1  (Q0I267), 
PFKA_HISS2  (B0UW05), PFKA_KLEP3  (B5XZ40), PFKA_KLEP7  (A6TGB8), 
PFKA_LACAC  (Q5FKG6), PFKA_LACDE  (P80019), PFKA_LACGA  (Q043V2), 
PFKA_LACH4  (A8YV22), PFKA_LACJO  (Q74JM8), PFKA_LACLA  (Q07636), 
PFKA_LACLM  (A2RKA2), PFKA_LACLS  (Q02YK5), PFKA_LACPL  (Q88VY1), 
PFKA_LACS1  (Q1WTT3), PFKA_LISIN  (Q92BE4), PFKA_LISMC  (C1KVL8), 
PFKA_LISMF  (Q71Z96), PFKA_LISMH  (B8DHH7), PFKA_LISMO  (Q8Y6W0), 
PFKA_LISW6  (A0AJ20), PFKA_LYSSH  (Q93LR4), PFKA_MACCJ  (B9E7A4), 
PFKA_MANSM  (Q65VM6), PFKA_MYCBO  (P65691), PFKA_MYCCT  (Q2SSQ6), 
PFKA_MYCH2  (Q601D3), PFKA_MYCH7  (Q4A8Q3), PFKA_MYCHJ  (Q4AAM2), 
PFKA_MYCLE  (O33106), PFKA_MYCMO  (Q6KHX0), PFKA_MYCPU  (Q98PW8), 
PFKA_MYCTO  (P9WID6), PFKA_MYCTU  (P9WID7), PFKA_NATTJ  (B2A6Y0), 
PFKA_OCEIH  (Q8EPD6), PFKA_PAEMC  (Q59214), PFKA_PASMU  (Q9CPH2), 
PFKA_PECAS  (Q6CZ46), PFKA_PECCP  (C6DHK2), PFKA_PEDPA  (Q03F74), 
PFKA_PEPD6  (Q180P4), PFKA_PHOPR  (Q6LVK2), PFKA_SALA4  (B5F0P6), 
PFKA_SALAR  (A9MI50), PFKA_SALCH  (Q57HF3), PFKA_SALDC  (B5FPR2), 
PFKA_SALEP  (B5QWZ5), PFKA_SALG2  (B5RFA9), PFKA_SALHS  (B4TCK0), 
PFKA_SALNS  (B4T049), PFKA_SALPA  (Q5PIR6), PFKA_SALPB  (A9MZE7), 
PFKA_SALPC  (C0Q414), PFKA_SALPK  (B5BJI2), PFKA_SALSV  (B4TPS6), 
PFKA_SALTI  (P65693), PFKA_SALTY  (P65692), PFKA_SCHMA  (Q27778), 
PFKA_SCHPO  (O42938), PFKA_SERP5  (A8GLB0), PFKA_SHIB3  (B2TVQ8), 
PFKA_SHIBS  (Q31U74), PFKA_SHIDS  (Q32A80), PFKA_SHIFL  (P0A798), 
PFKA_SHISS  (Q3YV62), PFKA_SODGM  (Q2NQX2), PFKA_SPICI  (P20275), 
PFKA_STAA2  (A6U2G5), PFKA_STAA9  (A5ITM2), PFKA_STAAB  (Q2YTE2), 
PFKA_STAAC  (Q5HF75), PFKA_STAAE  (A6QHN3), PFKA_STAAM  (P65694), 
PFKA_STAAN  (P99165), PFKA_STAAR  (Q6GG08), PFKA_STAAS  (Q6G8M8), 
PFKA_STAAT  (A8Z2L4), PFKA_STAAW  (P65695), PFKA_STACT  (B9DN94), 
PFKA_STAEQ  (Q5HNK6), PFKA_STAES  (Q8CS68), PFKA_STRA1  (Q3K1E6), 
PFKA_STRA3  (P65696), PFKA_STRA5  (P65697), PFKA_STRE4  (C0M8V6), 
PFKA_STREM  (B4U2M2), PFKA_STRGC  (A8AXW1), PFKA_STRMU  (Q8DTX6), 
PFKA_STRP1  (Q99ZD0), PFKA_STRP2  (Q04L24), PFKA_STRP3  (P0DD02), 
PFKA_STRP4  (B5E3Z8), PFKA_STRP6  (Q5XBV2), PFKA_STRP7  (C1C6M8), 
PFKA_STRP8  (Q8P0S6), PFKA_STRPB  (Q1JBF7), PFKA_STRPC  (Q1JLD9), 
PFKA_STRPD  (Q1JGH6), PFKA_STRPF  (Q1J694), PFKA_STRPG  (A2RE65), 
PFKA_STRPI  (B1IB66), PFKA_STRPJ  (B8ZNU0), PFKA_STRPM  (Q48T86), 
PFKA_STRPN  (Q97RC6), PFKA_STRPQ  (P0DD03), PFKA_STRPS  (B2IP53), 
PFKA_STRPZ  (B5XLV6), PFKA_STRR6  (Q8DQ85), PFKA_STRS7  (C0MGJ9), 
PFKA_STRSV  (A3CM69), PFKA_STRSY  (A4VTS0), PFKA_STRU0  (B9DSA4), 
PFKA_STRZJ  (C1CDP4), PFKA_STRZP  (C1CJY4), PFKA_STRZT  (C1CRZ7), 
PFKA_SULDN  (Q30T53), PFKA_SULNB  (A6QAB4), PFKA_TERTT  (C5BNR1), 
PFKA_THEEB  (Q8DJB1), PFKA_THEMA  (Q9WY52), PFKA_THENN  (B9K6R9), 
PFKA_THEP1  (A5IKL2), PFKA_THEP3  (B0K7U7), PFKA_THEPX  (B0K6L2), 
PFKA_THESQ  (B1L9U3), PFKA_THET2  (Q72H98), PFKA_THETN  (Q8R914), 
PFKA_TOLAT  (C4LEQ5), PFKA_VIBCB  (A7MX59), PFKA_VIBCH  (Q9KNP2), 
PFKA_VIBF1  (Q5E2B1), PFKA_VIBFM  (B5FBT1), PFKA_VIBPA  (Q87KX0), 
PFKA_VIBVU  (Q8DCY1), PFKA_VIBVY  (Q7MGW6), PFKA_WOLSU  (Q7M9C2), 
PFKA_YARLI  (P59680), PFKA_YERE8  (A1JHZ3), PFKA_YERP3  (A7FCW1), 
PFKA_YERPA  (Q1C297), PFKA_YERPB  (B2JZA3), PFKA_YERPE  (Q8ZJL6), 
PFKA_YERPG  (A9R6A3), PFKA_YERPN  (Q1CD33), PFKA_YERPP  (A4TSA7), 
PFKA_YERPS  (Q66GA8), PFKA_YERPY  (B1JQU4), PFP_AMYME   (Q59126), 
PFP_AMYMS   (Q9AGC0), PFP_DICTH   (Q9KH71), PFP_STRCO   (O08333)
» More

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

PFKA1_CLOPE (Q8XNH2), PFKA3_BACTN (Q8A2E9), PFKA_ENTFA  (Q836R3), 
PFKA_LACC3  (Q039I0), PFKA_LACCB  (B3WE64), PFKA_MYCGE  (P47457), 
PFKA_MYCPE  (Q8EVH2), PFKA_MYCPN  (P75476), PFKA_PERMH  (C0QQX4), 
PFKA_PROFC  (D7GCU5), PFKA_SPITD  (E0RTD9), PFKA_STRTD  (Q03KB7), 
PFKA_STRTR  (Q9L9E3), PFKA_SULSY  (B2V7W7), PFKA_UREPA  (Q9PQV8), 
PFP_THETK   (G4RK16)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

PFKA2_THET8 (P21778), PFKA_CALFI  (Q27543)

		
PDB
[Detailed view]
16 PDB

1MTO; 1PFK; 1ZXX; 2PFK; 3O8L; 3O8N; 3O8O; 3OPY; 3PFK; 3U39; 4A3S; 4I36; 4I4I; 4I7E; 4PFK; 6PFK
» More

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View entry in raw text format (no links)
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