Entry: PS00447

General information about the entry
Entry name DNA_POLYMERASE_A
Accession number PS00447
Entry type PATTERN
Date MAY-1991 (CREATED); NOV-1995 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00412
Name and characterization of the entry
DescriptionDNA polymerase family A signature.
Pattern R-x(2)-[GSAV]-K-x(3)-[LIVMFY]-[AGQ]-x(2)-Y-x(2)-[GS]-x(3)-[LIVMA].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 53 hits in 53 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 50 hits in 50 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 3 hits in 3 different sequences
  • Number of known missed hits: 5
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 94.34 %
  • Recall (true hits / (true hits + false negatives)): 90.91 %
Comments
  • Taxonomic range: Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
DPO1F_THETH (P30313), DPO1T_THET8 (P52028), DPO1_AQUAE  (O67779), 
DPO1_BACCA  (Q04957), DPO1_BACSU  (O34996), DPO1_BORBU  (O51498), 
DPO1_CALBD  (Q59156), DPO1_CHLAA  (O08307), DPO1_DEIRA  (P52027), 
DPO1_ECOLI  (P00582), DPO1_GEOSE  (P52026), DPO1_HAEIN  (P43741), 
DPO1_HELPJ  (Q9ZJE9), DPO1_HELPY  (P56105), DPO1_LACLA  (Q9CDS1), 
DPO1_LACLM  (O32801), DPO1_MYCBO  (P0A551), DPO1_MYCLE  (P46835), 
DPO1_MYCTU  (P0A550), DPO1_PSEAE  (Q9HT80), DPO1_RHILE  (Q9S1G2), 
DPO1_RICBR  (Q1RH76), DPO1_RICCN  (Q92GB7), DPO1_RICFE  (Q9RAA9), 
DPO1_RICHE  (Q9RLB6), DPO1_RICPR  (O05949), DPO1_RICTY  (Q9RLA0), 
DPO1_SALTY  (Q9F173), DPO1_STRPN  (P59199), DPO1_STRR6  (P59200), 
DPO1_THEAQ  (P19821), DPO1_THECA  (P80194), DPO1_THEFI  (O52225), 
DPO1_TREPA  (P74933), DPOG1_CHICK (Q92076), DPOG1_DROME (Q27607), 
DPOG1_HUMAN (P54098), DPOG1_MOUSE (P54099), DPOG1_RAT   (Q9QYV8), 
DPOG1_XENLA (Q91684), DPOG_NEUCR  (Q9Y767), DPOG_YEAST  (P15801), 
DPOLQ_HUMAN (O75417), DPOL_BPMD2  (O64235), DPOL_BPML5  (Q05254), 
DPOL_BPSP1  (P30314), DPOL_BPSP2  (P06225), DPOL_BPT3   (P20311), 
DPOL_BPT5   (P19822), DPOL_BPT7   (P00581)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
DPO1_SYNY3  (Q55971), DPOG_PICPA  (Q01941), DPOG_SCHPO  (Q12704), 
DPOLN_HUMAN (Q7Z5Q5), DPOLN_MOUSE (Q7TQ07)
False positive hits (sequences which do not belong to the set under consideration):
AGGC_ECOLX  (P46005), ARPB_ECOLI  (P76205), FA83B_MOUSE (Q0VBM2)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1BGX; 1D8Y; 1D9D; 1D9F; 1DPI; 1JXE; 1KFD; 1KFS; 1KLN; 1KRP; 1KSP; 1KTQ; 1L3S; 1L3T; 1L3U; 1L3V; 1L5U; 1LV5; 1NJX; 1NJY; 1NJZ; 1NK0; 1NK4; 1NK5; 1NK6; 1NK7; 1NK8; 1NK9; 1NKB; 1NKC; 1NKE; 1QSL; 1QSS; 1QSY; 1QTM; 1SKR; 1SKS; 1SKW; 1SL1; 1T7P; 1T8E; 1TAQ; 1TAU; 1TK0; 1TK8; 1TKD; 1U45; 1U47; 1U48; 1U49; 1U4B; 1UA1; 1X9M; 1X9S; 1X9W; 1XC9; 1XWL; 1ZYQ; 2AJQ; 2BDP; 2HHX; 2KFN; 2KFZ; 2KTQ; 2KZM; 2KZZ; 3BDP; 3EYZ; 3EZ5; 3IKM; 3KTQ; 3LWL; 3LWM; 3M8R; 3M8S; 3OJS; 3OJU; 3PO4; 3PO5; 3PY8; 3RR8; 3RRG; 3RRH; 3RTV; 3SV3; 3SV4; 3SYZ; 3SZ2; 3T3F; 4BDP; 4DF4; 4DF8; 4DFJ; 4DFK; 4DFM; 4DFP; 4DLE; 4DLG; 4ELT; 4ELU; 4KTQ; 5KTQ;

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