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PROSITE entry PS00673


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General information about the entry

Entry name [info] V8_SER
Accession [info] PS00673
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00571
Associated ProRule [info] PRU10083

Name and characterization of the entry

Description [info] Serine proteases, V8 family, serine active site.
Pattern [info]
T-x(2)-[GC]-[NQ]-S-G-S-x-[LIVM]-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 16 in 16 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 70
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 88.89 %
Recall (true positives / (true positives + false negatives)) 18.60 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
16 sequences

DPP11_SHEPC (A4Y3F4), ETA_STAAU   (P09331), ETB_STAAU   (P09332), 
GSEA_STAEP  (P0C0Q1), GSEA_STAEQ  (Q5HN75), GSEA_STAES  (P0C0Q2), 
GSEP_BACLD  (P80057), MPR_BACSU   (P39790), SSPA_STAA8  (Q2FZL2), 
SSPA_STAAC  (Q5HH35), SSPA_STAAM  (Q99V45), SSPA_STAAN  (Q7A6A6), 
SSPA_STAAR  (Q6GI34), SSPA_STAAS  (Q6GAG4), SSPA_STAAU  (P0C1U8), 
SSPA_STAAW  (Q8NX98)
» more

UniProtKB/Swiss-Prot
False negative sequences
70 sequences

SPLA1_STAAU (Q9FD08), SPLA2_STAAU (A5JJ15), SPLA_STAA1  (A7X3R0), 
SPLA_STAA2  (A6U2R9), SPLA_STAA3  (Q2FFS9), SPLA_STAA8  (Q2FXC2), 
SPLA_STAA9  (A5ITX8), SPLA_STAAC  (Q5HEW0), SPLA_STAAE  (A6QHZ6), 
SPLA_STAAM  (Q99T60), SPLA_STAAN  (Q7A4Y0), SPLA_STAAS  (Q6G8C1), 
SPLA_STAAT  (A8Z4N9), SPLA_STAAW  (Q8NVX5), SPLB_STAA1  (A7X3Q8), 
SPLB_STAA2  (A6U2R8), SPLB_STAA3  (Q2FFT0), SPLB_STAA8  (Q2FXC3), 
SPLB_STAA9  (A5ITX7), SPLB_STAAB  (Q2YTM3), SPLB_STAAC  (Q5HEW1), 
SPLB_STAAE  (A6QHZ5), SPLB_STAAM  (Q7A2Q7), SPLB_STAAN  (Q7A4Y1), 
SPLB_STAAS  (Q6G8C2), SPLB_STAAT  (A8Z4N8), SPLB_STAAU  (Q53781), 
SPLB_STAAW  (Q8NVX6), SPLC_STAA1  (A7X3Q7), SPLC_STAA2  (A6U2R7), 
SPLC_STAA3  (Q2FFT1), SPLC_STAA8  (Q2FXC4), SPLC_STAA9  (A5ITX6), 
SPLC_STAAB  (Q2YTM4), SPLC_STAAC  (Q5HEW2), SPLC_STAAE  (A6QHZ4), 
SPLC_STAAM  (Q7A2Q8), SPLC_STAAN  (Q7A4Y2), SPLC_STAAR  (Q6GFN8), 
SPLC_STAAS  (Q6G8C3), SPLC_STAAT  (A8Z4N7), SPLC_STAAU  (Q53782), 
SPLC_STAAW  (Q8NVX7), SPLD_STAA1  (A7X3Q6), SPLD_STAA3  (Q2FFT2), 
SPLD_STAA8  (Q2FXC5), SPLD_STAAC  (Q5HEW3), SPLD_STAAE  (A6QHZ3), 
SPLD_STAAM  (Q7A2Q9), SPLD_STAAN  (Q7A4Y3), SPLD_STAAT  (A8Z4N6), 
SPLE_STAA3  (Q2FFT3), SPLE_STAA8  (Q2FXC7), SPLE_STAAC  (Q5HEW4), 
SPLE_STAAE  (A6QHZ2), SPLE_STAAR  (Q6GFP0), SPLE_STAAT  (A8Z4N5), 
SPLE_STAAU  (Q9FD07), SPLF_STAA1  (A7X3Q5), SPLF_STAA2  (A6U2R6), 
SPLF_STAA3  (Q2FFT4), SPLF_STAA8  (Q2FXC8), SPLF_STAA9  (A5ITX5), 
SPLF_STAAC  (Q5HEW5), SPLF_STAAE  (A6QHZ1), SPLF_STAAM  (Q99T61), 
SPLF_STAAN  (Q7A4Y4), SPLF_STAAS  (Q6G8C4), SPLF_STAAT  (A8Z4N4), 
SPLF_STAAW  (Q8NVX8)
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

NUOM_MYCTO  (P9WIW4), NUOM_MYCTU  (P9WIW5)

		
PDB
[Detailed view]
12 PDB

1AGJ; 1DT2; 1DUA; 1EXF; 1QTF; 1QY6; 1WCZ; 2O8L; 4JCN; 6Q12; 6TYA; 6U1B