Entry: PS00972

Forthcoming changes to the profile format
General information about the entry

Entry name [info] USP_1
Accession [info] PS00972
Entry type [info] PATTERN
Date [info] JUN-1994 (CREATED); DEC-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10092

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 1.
Pattern [info]
G-[LIVMFY]-x(1,3)-[AGCY]-[NASMQG]-x-C-[FYWC]-[LIVMFCA]-[NSTAD]-[SACV]-x-
[LIVMSF]-[QF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 281 in 281 different sequences
Number of true positive hits 281 in 281 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 27
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.23 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
281 sequences

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5), 
CREB_ASPFU  (Q4WQI1), CREB_ASPNC  (A2Q9N1), CREB_ASPOR  (Q2UUG8), 
CREB_ASPTN  (Q0CT11), CREB_EMENI  (Q96V54), CREB_NEOFI  (A1CW53), 
CYLD_BOVIN  (Q1RMU2), CYLD_HUMAN  (Q9NQC7), CYLD_MOUSE  (Q80TQ2), 
CYLD_PONAB  (Q5RED8), CYLD_RAT    (Q66H62), FAF_DROME   (P55824), 
NOT_DROME   (Q9VVR1), U17L5_HUMAN (A8MUK1), U17L6_HUMAN (Q6QN14), 
U17L8_HUMAN (P0C7I0), U17LA_HUMAN (C9JJH3), U17LB_HUMAN (C9JVI0), 
U17LD_HUMAN (C9JLJ4), U17LF_HUMAN (C9J2P7), U17LH_HUMAN (D6RBQ6), 
U17LI_HUMAN (D6R9N7), U17LJ_HUMAN (D6RCP7), U17LK_HUMAN (D6RJB6), 
U17LL_HUMAN (D6R901), U17LM_HUMAN (D6RA61), U17LN_HUMAN (D6RBM5), 
U17LO_HUMAN (Q0WX57), U17PA_MOUSE (Q61068), U17PE_MOUSE (Q7M764), 
UB10A_XENLA (Q2NL57), UB10B_XENLA (Q7ZXR7), UB12A_XENLA (Q52KZ6), 
UB12B_XENLA (Q5M981), UB22A_XENLA (Q6GNI6), UB22B_XENLA (Q6DCJ1), 
UBP10_ARATH (Q9ZSB5), UBP10_BOVIN (A5PJS6), UBP10_CHICK (Q5ZJN4), 
UBP10_HUMAN (Q14694), UBP10_MOUSE (P52479), UBP10_RAT   (Q3KR59), 
UBP10_XENTR (Q6DIJ4), UBP11_ARATH (Q9MAQ3), UBP11_HUMAN (P51784), 
UBP11_MOUSE (Q99K46), UBP11_YEAST (P36026), UBP12_ARATH (Q9FPT1), 
UBP12_BOVIN (A5D9H7), UBP12_DANRE (A4FUN7), UBP12_HUMAN (O75317), 
UBP12_MOUSE (Q9D9M2), UBP12_SALSA (C0HB46), UBP12_SCHPO (O60079), 
UBP12_YEAST (P39538), UBP13_ARATH (Q84WU2), UBP13_BOVIN (E1BMF7), 
UBP13_CHICK (E1BY77), UBP13_HUMAN (Q92995), UBP13_MOUSE (Q5BKP2), 
UBP13_YEAST (P38187), UBP14_ARATH (Q8L6Y1), UBP14_BOVIN (Q0IIF7), 
UBP14_CAEEL (Q17361), UBP14_HUMAN (P54578), UBP14_MOUSE (Q9JMA1), 
UBP14_PANTR (P60051), UBP14_RABIT (P40826), UBP14_SCHPO (Q11119), 
UBP14_YEAST (P38237), UBP15_ARATH (Q9FPS9), UBP15_BOVIN (Q2HJE4), 
UBP15_HUMAN (Q9Y4E8), UBP15_MOUSE (Q8R5H1), UBP15_RAT   (Q9R085), 
UBP15_XENTR (F6Z5C0), UBP15_YEAST (P50101), UBP16_ARATH (Q9SB51), 
UBP16_BOVIN (Q08DA3), UBP16_DANRE (A8HAL1), UBP16_EMENI (P0CAQ1), 
UBP16_HUMAN (Q9Y5T5), UBP16_MACFA (Q4R6X7), UBP16_MOUSE (Q99LG0), 
UBP16_RAT   (Q2KJ09), UBP16_SCHPO (O74442), UBP16_XENLA (Q6PAW2), 
UBP16_XENTR (Q0VA64), UBP16_YEAST (Q02863), UBP17_ARATH (Q9FKP5), 
UBP18_ARATH (Q67XW5), UBP18_HUMAN (Q9UMW8), UBP18_MOUSE (Q9WTV6), 
UBP18_PONAB (Q5RE63), UBP19_ARATH (Q9SJA1), UBP19_HUMAN (O94966), 
UBP19_MOUSE (Q3UJD6), UBP19_RAT   (Q6J1Y9), UBP1_ARATH  (Q9FPT5), 
UBP1_BOVIN  (Q29RP1), UBP1_HUMAN  (O94782), UBP1_MOUSE  (Q8BJQ2), 
UBP1_RAT    (Q569C3), UBP1_SCHPO  (Q9USM5), UBP1_YEAST  (P25037), 
UBP20_ARATH (Q9FPS7), UBP20_BOVIN (A7Z056), UBP20_DANRE (A5PN09), 
UBP20_HUMAN (Q9Y2K6), UBP20_MOUSE (Q8C6M1), UBP20_PONAB (Q5R5Z6), 
UBP20_XENLA (B1WBD7), UBP20_XENTR (A0JM59), UBP21_ARATH (Q9FIQ1), 
UBP21_BOVIN (Q2KJ72), UBP21_HUMAN (Q9UK80), UBP21_MOUSE (Q9QZL6), 
UBP21_RAT   (B2GUX4), UBP21_SCHPO (Q9UTT1), UBP22_ARATH (Q9LEW0), 
UBP22_BOVIN (P0C8Z3), UBP22_DANRE (A6H8I0), UBP22_HUMAN (Q9UPT9), 
UBP22_MOUSE (Q5DU02), UBP23_ARATH (Q9FPS4), UBP24_ARATH (Q9FPS3), 
UBP24_HUMAN (Q9UPU5), UBP24_MOUSE (B1AY13), UBP25_ARATH (Q9FPS2), 
UBP25_HUMAN (Q9UHP3), UBP25_MOUSE (P57080), UBP26_ARATH (Q9SCJ9), 
UBP26_HUMAN (Q9BXU7), UBP26_MOUSE (Q99MX1), UBP26_ORYSI (A2XDG4), 
UBP26_ORYSJ (A3AF13), UBP27_ARATH (Q9FPS0), UBP27_HUMAN (A6NNY8), 
UBP27_MOUSE (Q8CEG8), UBP28_CHICK (Q5ZID5), UBP28_HUMAN (Q96RU2), 
UBP28_MOUSE (Q5I043), UBP28_RAT   (D3ZJ96), UBP29_HUMAN (Q9HBJ7), 
UBP29_MOUSE (Q9ES63), UBP2_ARATH  (Q8W4N3), UBP2_BOVIN  (Q2KHV7), 
UBP2_CHICK  (O57429), UBP2_HUMAN  (O75604), UBP2_KLULA  (O42726), 
UBP2_MOUSE  (O88623), UBP2_RAT    (Q5U349), UBP2_SCHPO  (Q9P3U0), 
UBP2_YEAST  (Q01476), UBP30_DANRE (A2BGT0), UBP30_HUMAN (Q70CQ3), 
UBP30_MOUSE (Q3UN04), UBP30_XENTR (A4QNN3), UBP31_HUMAN (Q70CQ4), 
UBP32_HUMAN (Q8NFA0), UBP33_BOVIN (A6QNM7), UBP33_DANRE (A5PMR2), 
UBP33_HUMAN (Q8TEY7), UBP33_MOUSE (Q8R5K2), UBP33_PONAB (Q5REG5), 
UBP33_XENTR (Q28CN3), UBP34_HUMAN (Q70CQ2), UBP34_MOUSE (Q6ZQ93), 
UBP35_HUMAN (Q9P2H5), UBP36_DROAN (B3M3M6), UBP36_DROER (B3NC86), 
UBP36_DROGR (B4IXE0), UBP36_DROME (Q9VRP5), UBP36_DROMO (B4KXJ5), 
UBP36_DROPS (Q2LZB1), UBP36_DROSE (B4HUI5), UBP36_DROSI (B4QIS3), 
UBP36_DROVI (B4LG38), UBP36_DROWI (B4MLR8), UBP36_DROYA (B4PIW8), 
UBP36_HUMAN (Q9P275), UBP36_MOUSE (B1AQJ2), UBP37_BOVIN (F1N5V1), 
UBP37_CANFA (E2RK09), UBP37_CHICK (E1C213), UBP37_DANRE (E7F6T8), 
UBP37_HUMAN (Q86T82), UBP37_MOUSE (Q8C0R0), UBP37_PIG   (F1SRY5), 
UBP38_HUMAN (Q8NB14), UBP38_MOUSE (Q8BW70), UBP3_ARATH  (O24454), 
UBP3_HUMAN  (Q9Y6I4), UBP3_MOUSE  (Q91W36), UBP3_SCHPO  (O94269), 
UBP3_YEAST  (Q01477), UBP40_HUMAN (Q9NVE5), UBP40_MOUSE (Q8BWR4), 
UBP41_HUMAN (Q3LFD5), UBP42_BOVIN (E1B9W9), UBP42_HUMAN (Q9H9J4), 
UBP42_MOUSE (B2RQC2), UBP42_RAT   (D3ZU96), UBP43_HUMAN (Q70EL4), 
UBP43_MOUSE (Q8BUM9), UBP44_AILME (D2HBJ8), UBP44_DANRE (Q7ZUM8), 
UBP44_HUMAN (Q9H0E7), UBP44_MOUSE (Q8C2S0), UBP44_XENTR (Q0V9G5), 
UBP45_HUMAN (Q70EL2), UBP45_MOUSE (Q8K387), UBP46_DANRE (A5WWB0), 
UBP46_HUMAN (P62068), UBP46_MOUSE (P62069), UBP46_PONAB (Q5RBQ4), 
UBP47_CHICK (E1C1R4), UBP47_HUMAN (Q96K76), UBP47_MOUSE (Q8BY87), 
UBP47_XENLA (Q5U252), UBP47_XENTR (A1A5G2), UBP49_HUMAN (Q70CQ1), 
UBP49_MOUSE (Q6P9L4), UBP4_ARATH  (Q8LAM0), UBP4_ASHGO  (Q754R5), 
UBP4_BOVIN  (A6QR55), UBP4_CANGA  (Q6FQF0), UBP4_HUMAN  (Q13107), 
UBP4_KLULA  (Q9HFS7), UBP4_MOUSE  (P35123), UBP4_PONAB  (Q5RCD3), 
UBP4_RAT    (B2GUZ1), UBP4_SCHPO  (O60139), UBP4_VANPO  (A7TGY3), 
UBP4_YEAS1  (B3LGK1), UBP4_YEAS7  (A6ZY34), UBP4_YEAST  (P32571), 
UBP50_HUMAN (Q70EL3), UBP50_MACFA (Q4R6D3), UBP50_MOUSE (Q6P8X6), 
UBP51_HUMAN (Q70EK9), UBP5_ARATH  (O22207), UBP5_HUMAN  (P45974), 
UBP5_MOUSE  (P56399), UBP5_SCHPO  (Q09879), UBP5_YEAST  (P39944), 
UBP6_ARATH  (Q949Y0), UBP6_HUMAN  (P35125), UBP6_SCHPO  (Q92353), 
UBP6_YEAST  (P43593), UBP7_ARATH  (Q84WC6), UBP7_CAEBR  (Q60MK8), 
UBP7_CAEEL  (Q7JKC3), UBP7_CHICK  (Q6U7I1), UBP7_DROME  (Q9VYQ8), 
UBP7_HUMAN  (Q93009), UBP7_MOUSE  (Q6A4J8), UBP7_RAT    (Q4VSI4), 
UBP7_SCHPO  (Q9P7S5), UBP7_YEAST  (P40453), UBP8_ARATH  (Q9C585), 
UBP8_HUMAN  (P40818), UBP8_MOUSE  (Q80U87), UBP8_SCHPO  (Q09738), 
UBP8_YEAST  (P50102), UBP9_ARATH  (Q93Y01), UBP9_YEAST  (P39967), 
UBPA_DICDI  (P54201), UBPE_DROME  (Q24574), UBPL1_MIMIV (Q5UQR3), 
UBPX_CAEEL  (P34547), UBPY_CAEEL  (Q09931), UL17C_HUMAN (C9JPN9), 
UP44A_XENLA (Q6NTR6), UP44B_XENLA (Q5XGZ2), USP9X_HUMAN (Q93008), 
USP9X_MOUSE (P70398), USP9Y_HUMAN (O00507)
» More

UniProtKB/Swiss-Prot
False negative sequences
27 sequences

SNUT2_HUMAN (Q53GS9), SNUT2_MOUSE (Q3TIX9), SNUT2_PONAB (Q5R761), 
U17L1_HUMAN (Q7RTZ2), U17L2_HUMAN (Q6R6M4), U17L3_HUMAN (A6NCW0), 
U17L4_HUMAN (A6NCW7), U17L7_HUMAN (P0C7H9), UBP10_SCHPO (Q9USR2), 
UBP10_YEAST (P53874), UBP11_SCHPO (Q9UUD6), UBP13_DANRE (F1QFS9), 
UBP13_XENTR (F6V6I0), UBP48_CHICK (Q5ZM45), UBP48_HUMAN (Q86UV5), 
UBP48_MOUSE (Q3V0C5), UBP48_RAT   (Q76LT8), UBP54_HUMAN (Q70EL1), 
UBP54_MOUSE (Q8BL06), UBP54_RAT   (Q6IE24), UBP5_PONAB  (Q5R407), 
UBP9_SCHPO  (Q9P7V9), UBPB_DICDI  (O96612), UBPL2_MIMIV (Q5UPW7), 
USPL1_DANRE (Q6DRC5), USPL1_HUMAN (Q5W0Q7), USPL1_MOUSE (Q3ULM6)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

UBP11_CANFA (Q01988)

		
PDB
[Detailed view]
23 PDB

1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2HD5; 2IBI; 2VHF; 2Y5B; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5; 4M5W; 4M5X
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission